Nursing Elites

1. What is the strongest evidence for evolution?

• A. The fossil record
• B. Comparative anatomy
• C. Biogeography
• D. All of the above

Correct answer: D

Rationale: A) The fossil record provides evidence of how organisms have changed over time, showing transitional forms and the progression of species. B) Comparative anatomy involves studying the similarities and differences in the structures of different species, which can reveal common ancestry and evolutionary relationships. C) Biogeography examines the distribution of species around the world, which can be explained by evolution and continental drift. By considering all of the above evidence together, scientists can build a comprehensive understanding of evolution and how species have changed and diversified over time.

2. What is the feedback mechanism in the endocrine system that helps maintain hormone balance?

• A. Positive feedback, where a hormone stimulates its own release
• B. Negative feedback, where a hormone suppresses its own release
• C. Cascade effect, where one hormone triggers the release of another
• D. Dual hormone system, where two hormones work together

Correct answer: B

Rationale: In the endocrine system, negative feedback is the mechanism by which hormone levels are regulated. When hormone levels reach a certain threshold, they signal the body to stop producing more of that hormone, thus maintaining a balance. Negative feedback (option B) is the correct answer as it helps in preventing overproduction of hormones by suppressing their own release. Positive feedback (option A) would lead to an excessive production of hormones, disrupting the balance. The cascade effect (option C) involves one hormone triggering the release of another but does not directly regulate hormone levels. The dual hormone system (option D) refers to two hormones working together but does not specifically address the feedback mechanism for maintaining hormone balance.

3. How can a single gene mutation lead to multiple phenotypes depending on the organism?

• A. Pleiotropy describes the effect of one gene influencing multiple seemingly unrelated traits.
• B. Epigenetics involves environmental factors modifying gene expression without altering the DNA sequence.
• C. Genetic drift refers to random changes in allele frequencies within a population.
• D. Gene regulation controls the timing and level of gene expression within an organism.

Correct answer: A

Rationale: A single gene mutation can lead to multiple phenotypes through pleiotropy, where one gene influences diverse traits or functions in an organism. This phenomenon occurs when the mutated gene affects different biochemical pathways, developmental processes, or cellular functions, resulting in a cascade of downstream effects that manifest as a variety of phenotypic outcomes. Choice B, epigenetics, involves modifications in gene expression influenced by environmental factors without altering the DNA sequence, which is not directly related to the question about single gene mutations causing multiple phenotypes. Choice C, genetic drift, refers to random changes in allele frequencies within a population, which is unrelated to the impact of a single gene mutation on multiple phenotypes. Choice D, gene regulation, focuses on controlling the timing and level of gene expression within an organism, which is not directly addressing how a single gene mutation can lead to diverse phenotypes.

4. Which hormone, produced by the ovaries, is responsible for the development of the uterine lining during the menstrual cycle and supports early pregnancy?

• A. Estrogen
• B. Progesterone
• C. Testosterone
• D. Prolactin

Correct answer: B

Rationale: Progesterone, produced by the ovaries, is responsible for the development of the uterine lining during the menstrual cycle and supports early pregnancy. While estrogen also plays a crucial role in the menstrual cycle, progesterone is specifically known for its role in preparing the uterus for pregnancy and maintaining the uterine lining. Testosterone is primarily a male sex hormone and not directly involved in these processes. Prolactin is a hormone that is mainly associated with milk production and not related to the development of the uterine lining or early pregnancy.

5. What is a mutation?

• A. A change in the DNA sequence
• B. A type of protein
• C. A normal part of the DNA replication process
• D. A harmless variation in DNA

Correct answer: A

Rationale: A mutation is defined as a change in the DNA sequence, which can occur due to various factors such as errors during DNA replication, exposure to mutagens (e.g., chemicals, radiation), or spontaneous changes. These alterations can lead to modifications in the genetic information carried by an organism, resulting in effects that can range from harmless variations to causing genetic disorders or diseases. Mutations play a crucial role in genetic diversity and evolution. Choices B, C, and D are incorrect as they do not accurately define what a mutation is. Option B is incorrect because mutations are not a type of protein but rather changes in DNA. Option C is incorrect because while mutations can occur during DNA replication, they are not considered a 'normal' part of the process as they can lead to genetic variations. Option D is incorrect because mutations can have a wide range of effects and are not always harmless variations.

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