HESI A2
HESI A2 Practice Test Biology
1. What happens during the S phase of the cell cycle?
- A. Chromosomes are duplicated.
- B. Cell growth occurs.
- C. DNA is synthesized.
- D. DNA is destroyed.
Correct answer: A
Rationale: During the S phase of the cell cycle, chromosomes are duplicated. This is a critical step in cell division as each chromosome is replicated to ensure that the resulting daughter cells receive an identical set of genetic information. Choices B, C, and D are incorrect because cell growth primarily occurs in the G1 phase, DNA synthesis happens during the S phase, and DNA destruction does not occur during any phase of the cell cycle.
2. The two catabolic pathways that lead to cellular energy production are:
- A. fermentation and protein synthesis
- B. cellular respiration and glycolysis
- C. fermentation and glycolysis
- D. cellular respiration and fermentation
Correct answer: D
Rationale: The correct answer is D: cellular respiration and fermentation. Cellular respiration involves the breakdown of glucose in the presence of oxygen to produce ATP, which is the primary source of energy for cells. Fermentation, on the other hand, occurs in the absence of oxygen and produces ATP through glycolysis followed by specific fermentation pathways. Choices A, B, and C are incorrect. Protein synthesis is a biosynthetic process, not a catabolic pathway for energy production. Glycolysis is a common step in both cellular respiration and fermentation, so it is not a pair of distinct catabolic pathways. Therefore, the most accurate pairing of catabolic pathways for cellular energy production is cellular respiration and fermentation.
3. During which phase is the chromosome number reduced from diploid to haploid?
- A. S phase
- B. interphase
- C. mitosis
- D. meiosis I
Correct answer: D
Rationale: The correct answer is 'meiosis I.' During meiosis I, the chromosome number is reduced from diploid to haploid through two rounds of division. Choice A ('S phase') is incorrect as the S phase is part of the cell cycle where DNA is replicated. Choice B ('interphase') is also incorrect as interphase is the phase where the cell prepares for division. Choice C ('mitosis') is incorrect as mitosis is a process where a diploid cell divides to produce two identical diploid daughter cells, maintaining the chromosome number.
4. Physical factors such as temperature and pH can alter enzyme activity because they have an effect on the enzyme's ___________.
- A. acidity
- B. shape
- C. chemistry
- D. substrate
Correct answer: B
Rationale: Physical factors such as temperature and pH can alter enzyme activity by affecting the enzyme's shape. Enzymes rely on their specific shapes to function properly and catalyze reactions. Any changes in temperature or pH can disrupt these shapes, causing the enzyme to become denatured and lose its functionality. Therefore, alterations in temperature and pH can impact enzyme activity by directly affecting their shapes. Choices A, C, and D are incorrect because while pH can affect acidity and chemical properties of the enzyme, and temperature can influence the enzyme-substrate interaction, the primary reason for enzyme activity alteration due to temperature and pH is the change in the enzyme's shape.
5. Which of the following is true of optical microscopy?
- A. Utilizes scanning electrons
- B. Utilizes visible light
- C. Utilizes dye for samples
- D. More than one of the above is true
Correct answer: D
Rationale: The correct answer is D, 'More than one of the above is true.' Optical microscopy utilizes visible light (Choice B) and often involves the use of dyes for samples (Choice C). Using dyes helps enhance contrast, making it easier to visualize the structures being observed. Choice A is incorrect as optical microscopy does not utilize scanning electrons, but rather visible light.
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