HESI A2
HESI A2 Biology Practice Test
1. Which organelle would you expect to be present in a cell responsible for detoxifying multiple molecules?
- A. rough ER
- B. smooth ER
- C. lysosome
- D. Golgi apparatus
Correct answer: B
Rationale: The smooth endoplasmic reticulum (ER) is the organelle responsible for detoxifying multiple molecules in a cell. It contains enzymes that help break down toxins and drugs, making it an essential organelle for detoxification processes. The rough ER, lysosome, and Golgi apparatus do not play direct roles in detoxification. The rough ER is mainly involved in protein synthesis and transport. Lysosomes are responsible for digestion and recycling within the cell. The Golgi apparatus is involved in modifying, sorting, and packaging proteins for secretion or for use within the cell.
2. Why does cellular respiration happen?
- A. Cells can copy DNA
- B. Cells can breathe
- C. Cells can convert nutrients to energy
- D. Cells can divide
Correct answer: C
Rationale: Cellular respiration is the process through which cells break down nutrients such as glucose to produce ATP (adenosine triphosphate), the energy currency of the cell. This process allows cells to extract energy from food molecules and use it for various cellular activities and functions. Choices A, B, and D are incorrect because cellular respiration is specifically about converting nutrients to energy, not about DNA copying, breathing, or cell division.
3. How should a researcher test the hypothesis that eating chocolate leads to acne in teenagers?
- A. Take 100 teenagers and feed each one a different amount of chocolate daily for 60 days; then test for acne.
- B. Take 100 teenagers and feed 50 two bars of chocolate daily for 60 days while the other 50 eat no chocolate; then test for acne.
- C. Take 1 teenager and feed him or her two bars of chocolate for 30 days and no chocolate for 30 days; then test for acne.
- D. Take 100 teenagers and feed them no chocolate for 30 days and two bars of chocolate apiece for 30 days; then test for acne.
Correct answer: B
Rationale: Option B is the correct approach to test the hypothesis that eating chocolate leads to acne in teenagers. This method involves having a control group (50 teenagers not consuming chocolate) and an experimental group (50 teenagers consuming two bars of chocolate daily), which allows for comparison. By having two distinct groups, researchers can assess the impact of chocolate consumption on acne development. Option A lacks a control group for comparison, making it harder to attribute any observed effects specifically to chocolate consumption. Option C only involves a single subject, which limits the generalizability of the results. Option D, where all teenagers experience both conditions, does not allow for a direct comparison between chocolate consumption and acne development, as all subjects are exposed to both conditions.
4. The fur color in a population of dogs is controlled by two alleles: black (B) and tan (b). The black allele exhibits complete dominance. If the phenotype of the dog is tan fur, what is its genotype?
- A. BB
- B. Bb
- C. bb
- D. Not enough information
Correct answer: C
Rationale: The correct answer is C: "bb." Since tan fur is the recessive trait controlled by the allele 'b,' the only possible genotype for a dog with tan fur is 'bb.' If a dog had the genotype 'BB' or 'Bb,' the dominant trait (black fur) would be expressed, not tan fur. Choice D, 'Not enough information,' is incorrect because based on the information provided, we can deduce the genotype of a dog with tan fur.
5. Which of the following organelles is responsible for producing ATP in cells?
- A. Nucleus
- B. Mitochondrion
- C. Chloroplast
- D. Lysosome
Correct answer: B
Rationale: The correct answer is 'Mitochondrion.' Mitochondria are known as the powerhouse of the cell and are responsible for producing ATP, the energy currency of the cell. The nucleus is responsible for storing genetic material and controlling cell activities, not for ATP production. Chloroplasts are found in plant cells and are responsible for photosynthesis, not ATP production. Lysosomes are involved in digestion and waste removal, not ATP production.
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