HESI A2
HESI A2 Biology 2024
1. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
2. Which cells in the human body lack nuclei?
- A. Nerve cells
- B. Red blood cells
- C. Liver cells
- D. Connective tissue cells
Correct answer: B
Rationale: Red blood cells, also known as erythrocytes, lack nuclei in humans. This absence of a nucleus allows more space for hemoglobin, the protein responsible for carrying oxygen, making red blood cells efficient at their function of oxygen transport in the body. Nerve cells (Choice A), liver cells (Choice C), and connective tissue cells (Choice D) all possess nuclei as they require genetic material for their functions, such as cell signaling, protein synthesis, and structural support.
3. Which of the following is always true about molecules?
- A. They cannot travel through all cell membranes
- B. They move from low concentration to high concentration without using energy
- C. They move from high concentration to low concentration without using energy
- D. They cannot move
Correct answer: C
Rationale: The statement that molecules move from high concentration to low concentration without using energy is always true due to the natural process of diffusion. This movement occurs to reach equilibrium and does not require any additional energy input directly from the molecule itself. Choice A is incorrect because not all molecules can travel through all cell membranes. Choice B is incorrect as molecules typically move from high concentration to low concentration in a process known as passive transport. Choice D is incorrect as molecules are in constant motion due to factors like temperature and kinetic energy.
4. Which of the following is false?
- A. Animal cells use lysosomes to break down old cells
- B. Animal cells use chloroplasts to gain energy
- C. Plant cells have a cell wall to maintain structure
- D. All of the above are true
Correct answer: B
Rationale: The statement "B. Animal cells use chloroplasts to gain energy" is false. Chloroplasts are only present in plant cells and certain algae, where they are responsible for photosynthesis to generate energy from sunlight. Animal cells rely on other organelles, such as mitochondria, for energy production. Choice A is true because animal cells use lysosomes to break down old cells and cellular waste. Choice C is true as plant cells have a cell wall composed of cellulose that provides structural support and protection.
5. Which of the following is an example of human error in an experiment?
- A. an imperfectly calibrated scale
- B. contaminating a sterile sample by breathing on it
- C. a draft in the laboratory slightly changing the temperature of a liquid
- D. failure to account for wind speed when measuring distance traveled
Correct answer: B
Rationale: Contaminating a sterile sample by breathing on it is an example of human error in an experiment because it involves an action directly caused by the researcher that compromises the integrity of the sample. Breathing on a sterile sample introduces external contaminants that can affect the results. Choices A, C, and D involve factors not directly under the researcher's control or are technical errors that do not involve direct human actions.
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