huntingtons disease is carried on the dominant allele in a situation where two heterozygous parents have the disease what percentage of their offsprin
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HESI A2

HESI A2 Biology 2024

1. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?

Correct answer: B

Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.

2. Which of the following is true of heterozygous traits?

Correct answer: D

Rationale: Heterozygous traits are denoted by having two different alleles for a particular gene, represented as Aa. This means that they are not haploid (A), not denoted AA (B), and not denoted aa (C). Therefore, the correct answer is D, as heterozygous traits are represented as Aa.

3. Which of the following animals would have the least energy efficiency in nutrient consumption?

Correct answer: A

Rationale: Cows are ruminant animals that have multiple stomachs and require large amounts of food to digest and convert into energy. They have lower energy efficiency compared to insects like caterpillars, coyotes, and crickets, which have more efficient nutrient consumption processes. The digestive system and metabolic functions of cows result in them having the least energy efficiency in nutrient consumption among the given choices. Caterpillars, coyotes, and crickets have more efficient nutrient consumption processes, making them more energy-efficient than cows.

4. Which of the following cell types has no nucleus?

Correct answer: B

Rationale: The correct answer is B, red blood cell. In humans, red blood cells do not have a nucleus. This unique feature allows them to have more space to carry oxygen efficiently. Platelets (choice A), white blood cells (choice C), and phagocytes (choice D) all have nuclei. Platelets are cell fragments, while white blood cells and phagocytes are types of immune cells that contain a nucleus for DNA and cellular functions.

5. Which of the following structures is not directly involved in translation?

Correct answer: D

Rationale: The correct answer is 'D: DNA.' DNA is not directly involved in translation, which is the process of synthesizing proteins from mRNA. tRNA carries amino acids to the ribosome, mRNA provides the template for protein synthesis, and ribosomes are the cellular machinery where translation occurs. DNA's main role is in transcription, where it serves as the template for mRNA synthesis, not in translation.

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