Nursing Elites

1. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?

• A. 0%
• B. 25%
• C. 50%
• D. 100%

Correct answer: B

Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.

2. Which organelle is responsible for making proteins?

• A. Ribosome
• B. Chloroplast
• C. Lysosome
• D. Mitochondrion

Correct answer: A

Rationale: Ribosomes are the organelles responsible for protein synthesis within the cell. They are the sites where amino acids are linked together to form proteins based on the instructions carried by mRNA (messenger RNA). Ribosomes can be found free-floating in the cytoplasm or attached to the endoplasmic reticulum, and they play a crucial role in translating genetic information into proteins. Chloroplasts are responsible for photosynthesis, lysosomes are involved in digestion and waste removal, and mitochondria are known as the powerhouse of the cell responsible for energy production through cellular respiration. Therefore, the ribosome is the correct organelle responsible for making proteins.

3. In an example of a male with hemophilia and a female carrier, what percentage of the offspring is predicted to be carriers only?

• A. 0%
• B. 25%
• C. 50%
• D. 100%

Correct answer: C

Rationale: In this scenario, the male offspring will inherit the X chromosome with the hemophilia gene from the mother, as males have one X chromosome inherited from their mother. The female offspring will inherit one normal X chromosome from the father and one X chromosome with the hemophilia gene from the mother, making them carriers of the hemophilia trait. Therefore, 50% of the offspring will be carriers only. Option A (0%) is incorrect as female offspring will inherit the X chromosome with the hemophilia gene from the mother. Option B (25%) is incorrect as the female offspring will not be unaffected. Option D (100%) is incorrect as not all offspring will be carriers, only the female offspring.

4. Which is true of gametes?

• A. They are diploid cells
• B. They are haploid cells
• C. They are somatic
• D. A & C are true

Correct answer: B

Rationale: Gametes are sex cells (sperm and eggs) that are involved in sexual reproduction. They are haploid cells, meaning they have half the number of chromosomes (n) compared to diploid cells. This is necessary for the formation of a diploid zygote when two gametes unite during fertilization. Somatic cells are non-reproductive cells in the body, so they are not gametes. Choice A is incorrect because gametes are not diploid but haploid. Choice C is incorrect because gametes are not somatic cells.

5. What are saturated fats saturated with?

• A. Hydrogen atoms
• B. Carbon atoms
• C. Oxygen atoms
• D. Nitrogen atoms

Correct answer: A

Rationale: Saturated fats are saturated with hydrogen atoms. This means that each carbon atom in the fatty acid chains forming saturated fats is bonded to as many hydrogen atoms as possible. This saturation results in the fatty acid chains being straight and closely packed together, making saturated fats solid at room temperature. Choice B (Carbon atoms), C (Oxygen atoms), and D (Nitrogen atoms) are incorrect because saturated fats are specifically saturated with hydrogen atoms, not carbon, oxygen, or nitrogen atoms.

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