Nursing Elites

1. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?

• A. 0%
• B. 25%
• C. 50%
• D. 100%

Correct answer: B

Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.

2. What type of cells are involved in meiosis (sex cells)?

• A. Somatic Cells
• B. Gametes
• C. Zygote
• D. Diploid Cells

Correct answer: B

Rationale: The correct answer is B, Gametes. Gametes are the specialized sex cells involved in meiosis, such as sperm and eggs. Somatic cells (A) are non-reproductive cells found in the body, not involved in meiosis. Zygote (C) is the result of fertilization, formed when gametes unite. Diploid cells (D) have two sets of chromosomes, but in meiosis, gametes are produced through a process of cell division that reduces the chromosome number by half to haploid.

3. Which part of cellular respiration produces the greatest amount of ATP?

• A. electron transport chain
• B. glycolysis
• C. citric acid cycle
• D. fermentation

Correct answer: A

Rationale: The electron transport chain (ETC) produces the greatest amount of ATP during cellular respiration. This process occurs in the inner mitochondrial membrane and involves the transfer of electrons through a series of protein complexes, creating a proton gradient that drives the synthesis of ATP. By utilizing the energy from the electron carriers NADH and FADH2 produced in earlier stages of cellular respiration, the ETC can generate a large amount of ATP efficiently through oxidative phosphorylation. Glycolysis only produces a small amount of ATP in comparison to the ETC. The citric acid cycle generates some ATP but not as much as the ETC. Fermentation does not produce ATP through oxidative phosphorylation and yields a much smaller amount of ATP compared to the ETC.

4. Where is DNA stored?

• A. The nucleus
• B. Ribosomes
• C. Endoplasmic reticulum
• D. Mitochondria

Correct answer: A

Rationale: DNA is stored in the nucleus of a cell. The nucleus houses the cell's genetic material, including the DNA, which contains the instructions for building and operating the cell. The nucleus controls the activities of the cell and is essential for proper cell function and reproduction. Ribosomes are responsible for protein synthesis, not DNA storage. The endoplasmic reticulum is involved in protein and lipid synthesis, storage, and transport but does not store DNA. Mitochondria are known as the powerhouse of the cell, producing energy in the form of ATP, but they do not store DNA.

5. RNA is made from DNA through a process called ___________.

• A. transcription
• B. synthesis
• C. translation
• D. replication

Correct answer: A

Rationale: RNA is made from DNA through a process called transcription. During transcription, an enzyme called RNA polymerase reads the DNA template and synthesizes a complementary RNA molecule. This process is essential for gene expression and allows the information encoded in DNA to be converted into functional RNA molecules. Choice B, 'synthesis,' is incorrect as it is a general term and does not specifically describe the process of RNA formation from DNA. Choice C, 'translation,' is incorrect as it refers to the process where the mRNA is used to assemble amino acids during protein synthesis, not the conversion of DNA to RNA. Choice D, 'replication,' is incorrect as it is the process of making an identical copy of DNA, not converting DNA into RNA.

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