huntingtons disease is carried on the dominant allele in a situation where two heterozygous parents have the disease what percentage of their offsprin
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HESI A2

HESI A2 Biology 2024

1. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?

Correct answer: B

Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.

2. Which of the following organelles are responsible for producing cell energy?

Correct answer: A

Rationale: The correct answer is A: Mitochondrion and chloroplast. Mitochondria and chloroplasts are the organelles responsible for producing cell energy through cellular respiration and photosynthesis, respectively. Choice B is incorrect because the nucleus is not involved in energy production. Choice C is incorrect as the nucleus is not an organelle that produces energy. Choice D is incorrect as lysosomes function in digesting waste materials, not in energy production.

3. What are plasma membranes mostly made of?

Correct answer: C

Rationale: The correct answer is C: Lipids. Plasma membranes are primarily composed of lipids, specifically phospholipids, which form a lipid bilayer. While proteins are also an essential component of plasma membranes, they are not the primary constituent. Carbohydrates are present on the outer surface of the membrane but are not the main structural component. Nucleotides are the building blocks of nucleic acids like DNA and RNA and are not the main constituents of plasma membranes.

4. Which of the following describes how a bacterium reproduces?

Correct answer: C

Rationale: Bacteria reproduce through a process called 'binary fission.' During binary fission, a bacterium duplicates its DNA and then divides into two identical daughter cells. This method is the primary way bacteria replicate. Choice A, 'Mitosis,' is incorrect because mitosis is a process specific to eukaryotic cells, where the nucleus divides to produce two identical nuclei. Choice B, 'Meiosis,' is incorrect as meiosis is a specialized type of cell division that produces gametes with half the chromosome number. Choice D, 'Cytokinesis,' is not the correct answer as cytokinesis is the physical process of cell division, which occurs after the genetic material has been divided in mitosis or meiosis.

5. When the genotype consists of a dominant and a recessive allele, the phenotype will be like the _ allele.

Correct answer: A

Rationale: When the genotype consists of a dominant and a recessive allele, the phenotype will be like the dominant allele. This is because dominant alleles typically mask the expression of recessive alleles. Therefore, the dominant allele will be expressed in the phenotype in most basic cases. The recessive allele will only be expressed phenotypically if the individual is homozygous recessive. Choice B, 'Recessive,' is incorrect because the phenotype will not be like the recessive allele in this case. Choice C, 'Both,' is incorrect because in simple dominant-recessive inheritance, the dominant allele will overshadow the recessive allele. Choice D, 'Neither,' is incorrect as the phenotype will resemble the dominant allele.

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