huntingtons disease is carried on the dominant allele in a situation where two heterozygous parents have the disease what percentage of their offsprin
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HESI A2

HESI A2 Biology 2024

1. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?

Correct answer: B

Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.

2. Which is true of the term Phenotype?

Correct answer: D

Rationale: The term "phenotype" refers to the observable characteristics or traits of an organism, which are determined by a combination of genotype (genetic makeup), epigenetic factors (modifications to gene expression), and environmental factors (external influences and experiences). Genotype, epigenetic factors, and environmental factors all play a role in determining an individual's phenotype, making option D the correct statement. Options A, B, and C are incorrect because the phenotype is not the genetic code, the phenotype does not determine the genotype, and it is the genotype that influences the phenotype, not the other way around.

3. Which organelle would you expect to be present in a cell responsible for detoxifying multiple molecules?

Correct answer: B

Rationale: The smooth endoplasmic reticulum (ER) is the organelle responsible for detoxifying multiple molecules in a cell. It contains enzymes that help break down toxins and drugs, making it an essential organelle for detoxification processes. The rough ER, lysosome, and Golgi apparatus do not play direct roles in detoxification. The rough ER is mainly involved in protein synthesis and transport. Lysosomes are responsible for digestion and recycling within the cell. The Golgi apparatus is involved in modifying, sorting, and packaging proteins for secretion or for use within the cell.

4. Which molecule is primarily responsible for storing energy in cells?

Correct answer: B

Rationale: ATP is the correct answer because it is the molecule responsible for storing and providing energy in cells. Glucose is a source of energy but not primarily for storage. Fatty acids are more involved in energy production through oxidation. Starch is a polysaccharide used for energy storage in plants.

5. What propels the cell forward?

Correct answer: B

Rationale: Propulsion, not microfilaments, cilia, or flagella, is what drives the cell forward. Propulsion is the force or process that propels the cell forward and allows it to move within its environment. Microfilaments are involved in cell structure, cilia are small hair-like structures for movement, and flagella are tail-like structures used for cell propulsion in some organisms.

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