HESI A2
HESI A2 Biology 2024
1. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
2. Which color of light is least effective at driving photosynthesis?
- A. Violet
- B. Green
- C. Orange
- D. Red
Correct answer: B
Rationale: Green light is the least effective at driving photosynthesis because chlorophyll, the primary pigment responsible for absorbing light in plants, does not absorb green light well. Instead, chlorophyll absorbs more effectively in the blue and red regions of the light spectrum. Therefore, green light is relatively less efficient in promoting photosynthesis compared to violet, orange, and red light. Violet light, although at the shorter wavelength end of the spectrum, can still drive photosynthesis better than green light. Orange and red light are more efficiently absorbed by chlorophyll, making them more effective in driving the process of photosynthesis.
3. Which part of cellular respiration produces the greatest amount of ATP?
- A. electron transport chain
- B. glycolysis
- C. citric acid cycle
- D. fermentation
Correct answer: A
Rationale: The electron transport chain (ETC) produces the greatest amount of ATP during cellular respiration. This process occurs in the inner mitochondrial membrane and involves the transfer of electrons through a series of protein complexes, creating a proton gradient that drives the synthesis of ATP. By utilizing the energy from the electron carriers NADH and FADH2 produced in earlier stages of cellular respiration, the ETC can generate a large amount of ATP efficiently through oxidative phosphorylation. Glycolysis only produces a small amount of ATP in comparison to the ETC. The citric acid cycle generates some ATP but not as much as the ETC. Fermentation does not produce ATP through oxidative phosphorylation and yields a much smaller amount of ATP compared to the ETC.
4. What is the role of tRNA during protein synthesis?
- A. Carries amino acids to the ribosome
- B. Links nucleotides together
- C. Copies DNA sequences
- D. Replicates genetic material
Correct answer: A
Rationale: During protein synthesis, tRNA plays the crucial role of carrying amino acids to the ribosome. This process ensures that the correct amino acids are brought to the ribosome according to the mRNA sequence. Choice B, linking nucleotides together, refers to the role of RNA polymerase in transcription, not tRNA. Choice C, copying DNA sequences, is the function of DNA polymerase during DNA replication, while choice D, replicating genetic material, is an overarching function of DNA replication, not specific to tRNA's role in protein synthesis.
5. Which animal has an open transport system?
- A. Grasshopper
- B. Earthworm
- C. Dolphin
- D. Chicken
Correct answer: B
Rationale: The correct answer is B: Earthworm. Earthworms have an open circulatory system, meaning their blood and interstitial fluid are not enclosed in blood vessels. Instead, the blood flows freely within the body cavity, allowing for direct exchange of nutrients and waste products with surrounding tissues. This lack of a closed transport system is a characteristic feature of earthworms. Choices A, C, and D are incorrect because grasshoppers, dolphins, and chickens have closed circulatory systems where the blood is enclosed within blood vessels, unlike earthworms.
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