huntingtons disease is carried on the dominant allele in a situation where two heterozygous parents have the disease what percentage of their offsprin
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HESI A2

HESI A2 Biology 2024

1. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?

Correct answer: B

Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.

2. How should a researcher test the hypothesis that practicing yoga reduces blood pressure?

Correct answer: B

Rationale: Option B is the most appropriate way to test the hypothesis that practicing yoga reduces blood pressure. By dividing 30 female participants into two groups with similar average blood pressure levels and testing each participant's blood pressure after participating in a yoga class, the researcher can effectively evaluate the impact of yoga on blood pressure. This design allows for a comparison between the two groups, helping to isolate the effects of yoga practice on blood pressure. Option A only involves one male and one female participant, which may not provide a representative sample. Option C introduces an additional variable of watching television, which could confound the results. Option D lacks consistency in the experimental design by switching the activities between men and women, making it difficult to attribute any observed changes solely to yoga practice.

3. The phases of mitosis include:

Correct answer: C

Rationale: The correct phases of mitosis are prophase, prometaphase, metaphase, anaphase, and telophase. Prophase is the first phase where chromatin condenses into chromosomes, the nuclear envelope breaks down, and the mitotic spindle forms. Prometaphase follows prophase, involving the full disintegration of the nuclear envelope and the attachment of spindle fibers to the kinetochores of the chromosomes. Metaphase is where chromosomes align along the metaphase plate. Anaphase is the phase where sister chromatids separate and move towards opposite poles. Telophase marks the final stage of mitosis, involving the decondensation of chromosomes and the reformation of the nuclear envelope. Choice A is incorrect because it includes interphase, which is not a phase of mitosis. Choice B is incorrect as it repeats prophase, which is the initial phase. Choice D is incorrect because it includes interphase and repeats prophase.

4. During protein synthesis, what process uses an RNA strand to produce a complementary strand of DNA?

Correct answer: A

Rationale: The correct answer is 'Transcription.' During transcription, an RNA strand is used to produce a complementary strand of DNA. This process is essential for converting the genetic information stored in DNA into RNA. Choice B, 'Translation,' is incorrect as it involves the synthesis of proteins from mRNA. Choice C, 'Transfer synthesis,' is not a recognized term in molecular biology. Choice D, 'Codon synthesis,' is also incorrect as it does not refer to the process of using an RNA strand to produce a complementary DNA strand.

5. When plants do not receive enough water, their photosynthetic rate drops. This is because:

Correct answer: A

Rationale: When plants do not receive enough water, their photosynthetic rate drops because water is a raw material required for the light reactions in photosynthesis. In the light reactions, water is split to provide electrons, which are then utilized to produce energy carriers used in converting carbon dioxide into glucose during the Calvin cycle. Therefore, without sufficient water, the light reactions cannot proceed effectively, ultimately leading to a decrease in photosynthetic rate. Choice B is incorrect because carbon dioxide is a separate raw material needed for the Calvin cycle, not the light reactions. Choice C is incorrect as water provides electrons, not carbon atoms, for photosynthesis. Choice D is incorrect because fermentation is not directly related to photosynthesis; oxygen is produced during photosynthesis, not fermentation.

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