HESI A2
Biology HESI A2 Practice Test
1. Select the strand of DNA that would match this segment: ACTTGCA
- A. TGAACGT
- B. GACCATG
- C. ACTTGCA
- D. None of the above
Correct answer: A
Rationale: The correct match for the DNA segment ACTTGCA is TGAACGT. In DNA, adenine (A) always pairs with thymine (T), and cytosine (C) always pairs with guanine (G). Therefore, the complementary strand to ACTTGCA should be TGAACGT, making choice A the correct answer. Choice B (GACCATG) does not follow the base pairing rules; hence, it is incorrect. Choice C (ACTTGCA) is the original segment, not its complementary strand. Choice D is incorrect as well because a matching strand does exist.
2. Which of the following is not true about enzymes?
- A. They catalyze reactions
- B. They lower the activation energy needed
- C. They have an active site
- D. They are typically proteins
Correct answer: B
Rationale: Enzymes lower the activation energy needed for a reaction to occur, not raise it. By lowering the activation energy, enzymes facilitate reactions, making them occur more easily and rapidly. Choice A is correct as enzymes indeed catalyze reactions. Choice C is correct as enzymes have specific active sites where substrates bind. Choice D is correct as enzymes are commonly proteins, although some RNA molecules also exhibit catalytic properties.
3. Which is true of gametes?
- A. They are diploid cells
- B. They are haploid cells
- C. They are somatic
- D. A & C are true
Correct answer: B
Rationale: Gametes are sex cells (sperm and eggs) that are involved in sexual reproduction. They are haploid cells, meaning they have half the number of chromosomes (n) compared to diploid cells. This is necessary for the formation of a diploid zygote when two gametes unite during fertilization. Somatic cells are non-reproductive cells in the body, so they are not gametes. Choice A is incorrect because gametes are not diploid but haploid. Choice C is incorrect because gametes are not somatic cells.
4. The procedure to focus an image using a compound microscope involves
- A. Adjusting the coarse adjustment each time a new magnification is selected
- B. Adjusting the fine adjustment each time a new magnification is selected
- C. Adjusting the stage each time a new magnification is selected
- D. All of the above
Correct answer: B
Rationale: When using a compound microscope, it is essential to adjust the fine adjustment knob each time you switch to a new magnification level. The fine adjustment knob allows for precise focusing on the specimen at different magnifications, ensuring a clear and sharp image. The coarse adjustment knob is typically used only at the lower magnification settings to bring the image into view roughly. Adjusting the stage may be necessary based on the size and thickness of the specimen, but it does not need to be done every time a new magnification is selected. Therefore, option B is the correct choice as it focuses on the key aspect of precise focusing during magnification changes.
5. During which phase of mitosis does the nuclear envelope disintegrate?
- A. Prophase
- B. Prophase
- C. Prometaphase
- D. Metaphase
Correct answer: C
Rationale: During the prometaphase stage of mitosis, the nuclear envelope disintegrates. This allows the condensed chromosomes to move towards the center of the cell, preparing for their alignment along the metaphase plate. The breakdown of the nuclear envelope is a crucial step in mitosis to ensure the proper segregation of genetic material into daughter cells. Choices A, B, and D are incorrect as the nuclear envelope disintegration specifically occurs during the prometaphase stage, not in prophase or metaphase.
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