HESI A2
HESI A2 Biology Practice Test
1. The difference between diploid and haploid is as follows:
- A. Diploid organisms are multicellular
- B. Diploid cells are somatic
- C. Diploid cells have two sets of homologous chromosomes
- D. More than one of the above is true
Correct answer: D
Rationale: Option B correctly states that diploid cells are somatic cells that make up the body tissues and organs in an organism, while haploid cells are gametes involved in sexual reproduction. Option C accurately differentiates diploid and haploid cells based on their chromosome sets – diploid cells have two sets of homologous chromosomes (one from each parent), whereas haploid cells have one set of unpaired chromosomes. Therefore, the correct choice is D, as both statements in options B and C are accurate descriptions of the differences between diploid and haploid cells. Option A is incorrect because diploid and haploid refer to the number of sets of chromosomes in a cell, not whether the organism is multicellular or not.
2. Select the option that best shows complementary base pairing in DNA:
- A. A and G
- B. A and C
- C. A and A
- D. A and T
Correct answer: D
Rationale: The correct answer is D. A purine (A) must pair with a pyrimidine (T) in DNA. This eliminates options A and C as they do not follow the rule of complementary base pairing. Adenine (A) always pairs with thymine (T) due to their specific shape and bonding properties in DNA structure. Choice B is incorrect because adenine does not pair with cytosine in DNA.
3. The two catabolic pathways that lead to cellular energy production are:
- A. fermentation and protein synthesis
- B. cellular respiration and glycolysis
- C. fermentation and glycolysis
- D. cellular respiration and fermentation
Correct answer: D
Rationale: The correct answer is D: cellular respiration and fermentation. Cellular respiration involves the breakdown of glucose in the presence of oxygen to produce ATP, which is the primary source of energy for cells. Fermentation, on the other hand, occurs in the absence of oxygen and produces ATP through glycolysis followed by specific fermentation pathways. Choices A, B, and C are incorrect. Protein synthesis is a biosynthetic process, not a catabolic pathway for energy production. Glycolysis is a common step in both cellular respiration and fermentation, so it is not a pair of distinct catabolic pathways. Therefore, the most accurate pairing of catabolic pathways for cellular energy production is cellular respiration and fermentation.
4. How are lipids different from other organic molecules?
- A. They are indivisible.
- B. They are not water soluble.
- C. They contain zinc.
- D. They form long proteins.
Correct answer: B
Rationale: The correct answer is B: 'They are not water soluble.' Lipids are not water-soluble, which distinguishes them from other organic molecules. Choice A is incorrect because lipids are not indivisible; they can be broken down into fatty acids and glycerol. Choice C is incorrect as lipids do not necessarily contain zinc; they are a diverse group of molecules. Choice D is incorrect because lipids do not form long proteins; proteins are made up of amino acids, not lipids.
5. The apical side of an epithelial cell:
- A. Is exposed to fluid or air
- B. Is on the bottom side of the cell
- C. Does not allow any substances to pass through
- D. None of the above
Correct answer: A
Rationale: The apical side of an epithelial cell is the top side, which is typically exposed to fluids, air, or the inside of an organ. This side allows substances to pass through it, facilitating the absorption, secretion, or excretion of various substances. Choice B is incorrect as the apical side is not on the bottom but the top side. Choice C is incorrect as the apical side does allow substances to pass through. Choice D is incorrect as there are characteristics associated with the apical side.
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