HESI A2
HESI A2 Biology Practice Test
1. The difference between diploid and haploid is as follows:
- A. Diploid organisms are multicellular
- B. Diploid cells are somatic
- C. Diploid cells have two sets of homologous chromosomes
- D. More than one of the above is true
Correct answer: D
Rationale: Option B correctly states that diploid cells are somatic cells that make up the body tissues and organs in an organism, while haploid cells are gametes involved in sexual reproduction. Option C accurately differentiates diploid and haploid cells based on their chromosome sets – diploid cells have two sets of homologous chromosomes (one from each parent), whereas haploid cells have one set of unpaired chromosomes. Therefore, the correct choice is D, as both statements in options B and C are accurate descriptions of the differences between diploid and haploid cells. Option A is incorrect because diploid and haploid refer to the number of sets of chromosomes in a cell, not whether the organism is multicellular or not.
2. What takes place in a lysosome?
- A. Ribosomes are made.
- B. Food is produced.
- C. Water is stored.
- D. Food is digested.
Correct answer: D
Rationale: In a lysosome, food particles are digested through the action of enzymes. Lysosomes are membrane-bound organelles containing digestive enzymes that break down large molecules into smaller ones, allowing the cell to utilize the nutrients for energy and other processes. Choices A, B, and C are incorrect because ribosomes are not made in lysosomes, food is not produced in lysosomes, and lysosomes do not store water.
3. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
4. Which structure controls the passage of substances into and out of the cell?
- A. Vacuole
- B. Cell Membrane
- C. Nuclear Membrane
- D. Cytoplasm
Correct answer: B
Rationale: The correct answer is the Cell Membrane. The cell membrane acts as a barrier that controls the passage of substances into and out of the cell. It is selectively permeable, allowing only certain molecules to pass through. Vacuole (Choice A), Nuclear Membrane (Choice C), and Cytoplasm (Choice D) do not primarily regulate the passage of substances in and out of the cell. Vacuoles are responsible for storage, the nuclear membrane surrounds the nucleus providing protection, and the cytoplasm is the fluid where organelles are suspended.
5. Three students measured the mass of a product of combustion. They recorded measurements of 14 g, 16 g, and 17 g. If the known mass of the product is 30 g, how would you describe the students’ measurements?
- A. Accurate
- B. Precise
- C. Both accurate and precise
- D. Neither accurate nor precise
Correct answer: B
Rationale: The students' measurements are precise because they are consistently close to each other. However, they are not accurate because all the measurements deviate from the known mass of the product (30 g). Accuracy refers to how close a measurement is to the true or accepted value, while precision refers to the level of agreement among repeated measurements. Since the students' measurements are consistent but do not align with the true value, they can be considered precise but not accurate. Choice A is incorrect because accuracy relates to the proximity of the measurements to the true value, which is not the case here. Choice C is incorrect because although the measurements are precise, they are not accurate. Choice D is incorrect because the measurements are precise as they show good agreement with each other, even though they are not accurate.
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