HESI A2
HESI A2 Biology 2024
1. Which molecules contain only carbon, hydrogen, and oxygen?
- A. Lipids and proteins
- B. Carbohydrates and lipids
- C. Proteins and carbohydrates
- D. Nucleic acids and proteins
Correct answer: B
Rationale: Carbohydrates and lipids are the molecules that contain only carbon, hydrogen, and oxygen. Carbohydrates such as sugars and starches are made up of carbon, hydrogen, and oxygen in a ratio of 1:2:1, while lipids such as fats and oils are composed of carbon, hydrogen, and oxygen as well. Lipids typically contain more carbon and hydrogen atoms compared to oxygen atoms. Proteins contain nitrogen in addition to carbon, hydrogen, and oxygen, while nucleic acids contain phosphorus in addition to carbon, hydrogen, and oxygen. Therefore, choices A, C, and D are incorrect as they include molecules that contain elements other than carbon, hydrogen, and oxygen.
2. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
3. During which phase of mitosis do the chromosomes align in the center of the cell?
- A. Prophase
- B. Metaphase
- C. Telophase
- D. Anaphase
Correct answer: B
Rationale: The correct answer is Metaphase. During Metaphase, the chromosomes line up along the center of the cell's equator, forming the metaphase plate. This alignment ensures that during the subsequent phase, Anaphase, the sister chromatids can separate and move towards opposite poles. Prophase is the initial phase of mitosis where chromosomes condense and the nuclear envelope breaks down. Telophase is the final phase of mitosis where two new nuclei form.
4. What molecule is primarily responsible for providing energy to the cell?
- A. ATP
- B. DNA
- C. ADP
- D. Glycogen
Correct answer: A
Rationale: Correct! ATP (Adenosine Triphosphate) is the main molecule that stores and provides energy for cellular activities. ATP is known as the energy currency of the cell, where energy released from the breakdown of nutrients is stored in the high-energy phosphate bonds of ATP. Choices B, C, and D are incorrect because DNA carries genetic information, ADP is the precursor of ATP, and glycogen is a polysaccharide used for energy storage, not direct energy provision.
5. How should a researcher test the hypothesis that a particular species of bird vocalizes most in the hours around dawn?
- A. Observe a flock of the birds in captivity and record them at two-hour intervals from predawn until sunset for a month.
- B. Observe a flock of the birds in the wild and record them at one-hour intervals from predawn until sunset in several seasons.
- C. Observe a flock of the birds in the wild and record them in predawn and postdawn hours every day for six months.
- D. Observe a flock of the birds in the wild, record them at one-hour intervals for a month, and compare that recording to recordings of other species.
Correct answer: C
Rationale: Observing a flock of the birds in the wild and recording them in predawn and postdawn hours every day for six months would be the best way to test the hypothesis that a particular species of bird vocalizes most in the hours around dawn. This method allows for consistent monitoring of the birds during specific times of interest over an extended period, providing a comprehensive dataset to accurately analyze the vocalization patterns. Options A and B do not focus specifically on dawn hours, making them less suitable for testing the hypothesis. Option D introduces a comparison with other species, which is unnecessary and distracts from the main objective of studying the vocalization pattern of the particular bird species around dawn.
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