HESI A2
HESI A2 Biology 2024
1. Which molecules contain only carbon, hydrogen, and oxygen?
- A. Lipids and proteins
- B. Carbohydrates and lipids
- C. Proteins and carbohydrates
- D. Nucleic acids and proteins
Correct answer: B
Rationale: Carbohydrates and lipids are the molecules that contain only carbon, hydrogen, and oxygen. Carbohydrates such as sugars and starches are made up of carbon, hydrogen, and oxygen in a ratio of 1:2:1, while lipids such as fats and oils are composed of carbon, hydrogen, and oxygen as well. Lipids typically contain more carbon and hydrogen atoms compared to oxygen atoms. Proteins contain nitrogen in addition to carbon, hydrogen, and oxygen, while nucleic acids contain phosphorus in addition to carbon, hydrogen, and oxygen. Therefore, choices A, C, and D are incorrect as they include molecules that contain elements other than carbon, hydrogen, and oxygen.
2. What organelle in the cell produces energy through the process of respiration?
- A. Nucleus
- B. Mitochondria
- C. Golgi Apparatus
- D. Chloroplasts
Correct answer: B
Rationale: The correct answer is B: Mitochondria. The mitochondria are known as the powerhouse of the cell and are responsible for producing energy through respiration in eukaryotic cells. Choice A, the Nucleus, is not involved in energy production but rather houses the cell's genetic material. Choice C, the Golgi Apparatus, is responsible for packaging and processing proteins, not energy production. Choice D, Chloroplasts, are responsible for photosynthesis in plant cells, not respiration for energy production.
3. Which type of passive transport uses proteins that change shape to move a target molecule through the membrane?
- A. Diffusion
- B. Carrier proteins
- C. Channel proteins
- D. None of the above
Correct answer: B
Rationale: The correct answer is B: Carrier proteins. Carrier proteins are involved in facilitated diffusion, a type of passive transport where specific target molecules are moved across the membrane with the help of proteins that change shape. These carrier proteins bind to the target molecule on one side of the membrane, undergo a conformational change, and then release the molecule on the other side. This process is crucial for the selective transport of certain molecules that cannot pass through the membrane by simple diffusion. Choices A and C are incorrect because diffusion and channel proteins do not involve proteins that change shape to transport target molecules selectively. Choice D is incorrect as carrier proteins fit the description provided in the question.
4. What happens to glucose during glycolysis?
- A. Its energy is entirely lost.
- B. It splits into molecules of pyruvic acid.
- C. It is stored in NADH.
- D. It joins with molecules of citric acid.
Correct answer: B
Rationale: During glycolysis, glucose undergoes a series of enzymatic reactions in the cytoplasm of the cell, resulting in its breakdown into two molecules of pyruvic acid. This process also generates ATP and NADH as energy carriers. Choice A is incorrect because glucose is not entirely lost, but rather converted into other molecules. Choice C is incorrect because NADH is a product of glycolysis, not a storage form for glucose. Choice D is incorrect as glucose does not join with molecules of citric acid during glycolysis, but rather in subsequent stages of cellular respiration.
5. Which of the following is not true about enzymes?
- A. They catalyze reactions
- B. They lower the activation energy needed
- C. They have an active site
- D. They are typically proteins
Correct answer: B
Rationale: Enzymes lower the activation energy needed for a reaction to occur, not raise it. By lowering the activation energy, enzymes facilitate reactions, making them occur more easily and rapidly. Choice A is correct as enzymes indeed catalyze reactions. Choice C is correct as enzymes have specific active sites where substrates bind. Choice D is correct as enzymes are commonly proteins, although some RNA molecules also exhibit catalytic properties.
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