HESI A2
HESI A2 Biology 2024
1. Patient A, who weighs 68 kilograms, steps onto a scale 20 times. The scale consistently weighs Patient A as 75 kilograms. What is true of the measurement?
- A. It is valid, but not reliable.
- B. It is reliable, but not valid.
- C. It is both valid and reliable.
- D. It is neither reliable nor valid.
Correct answer: B
Rationale: The correct answer is B: 'It is reliable, but not valid.' The measurement is reliable because it consistently provides the same result (75 kg). However, it is not valid because it does not accurately reflect the true weight of Patient A (68 kg). Choice A is incorrect because if the scale consistently shows the same weight (75 kg), it is reliable. Choice C is incorrect because although the scale is consistent, the measurement does not reflect the true weight, making it not valid. Choice D is incorrect as the measurement is reliable but lacks validity.
2. The phases of mitosis include:
- A. Prophase, interphase, metaphase, anaphase, and telophase
- B. Prophase, prophase, metaphase, anaphase, and cytokinesis
- C. Prophase, prometaphase, metaphase, anaphase, and telophase
- D. Prophase, interphase, prophase, anaphase, and telophase
Correct answer: C
Rationale: The correct phases of mitosis are prophase, prometaphase, metaphase, anaphase, and telophase. Prophase is the first phase where chromatin condenses into chromosomes, the nuclear envelope breaks down, and the mitotic spindle forms. Prometaphase follows prophase, involving the full disintegration of the nuclear envelope and the attachment of spindle fibers to the kinetochores of the chromosomes. Metaphase is where chromosomes align along the metaphase plate. Anaphase is the phase where sister chromatids separate and move towards opposite poles. Telophase marks the final stage of mitosis, involving the decondensation of chromosomes and the reformation of the nuclear envelope. Choice A is incorrect because it includes interphase, which is not a phase of mitosis. Choice B is incorrect as it repeats prophase, which is the initial phase. Choice D is incorrect because it includes interphase and repeats prophase.
3. What kind of bond connects sugar and phosphate in DNA?
- A. hydrogen
- B. ionic
- C. covalent
- D. overt
Correct answer: C
Rationale: Sugar and phosphate are indeed connected by covalent bonds in DNA. Covalent bonds involve the sharing of electrons between atoms, which is essential for forming the backbone of the DNA molecule. Hydrogen bonds (Choice A) are important in holding the nitrogenous bases together in the DNA double helix but do not connect sugar and phosphate. Ionic bonds (Choice B) involve the transfer of electrons between atoms and are not the primary bond connecting sugar and phosphate in DNA. 'Overt' (Choice D) is not a type of chemical bond and is an incorrect distractor.
4. Why is the nucleus important in a cell?
- A. It stores the DNA
- B. It supports the cell
- C. It makes protein
- D. It makes energy out of food
Correct answer: A
Rationale: The nucleus is important in a cell because it stores the DNA, which contains the genetic information necessary for the cell's function and replication. This genetic material controls the cell's activities and characteristics. Choices B, C, and D are incorrect because supporting the cell, making proteins, and producing energy are functions typically associated with other cell organelles like the cytoskeleton, ribosomes, and mitochondria, respectively.
5. Which organelle is found in protists but not in monerans?
- A. Golgi apparatus
- B. Chromosome
- C. Cytoplasm
- D. Cell membrane
Correct answer: A
Rationale: The Golgi apparatus is the correct answer. The Golgi apparatus is a cellular organelle responsible for processing and packaging proteins before they are transported to their final destination. Protists, being eukaryotic organisms, have membrane-bound organelles including the Golgi apparatus, which are absent in monerans. Monerans are prokaryotic organisms that lack membrane-bound structures such as the Golgi apparatus. Choices B, C, and D are incorrect as chromosomes, cytoplasm, and cell membranes are present in both protists and monerans.
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