HESI A2
HESI A2 Biology Practice Test
1. Prokaryotic cells:
- A. Have a nucleus
- B. Have a capsule
- C. Have membrane-bound organelles
- D. Cannot move on their own
Correct answer: B
Rationale: Prokaryotic cells do not have a nucleus or membrane-bound organelles. One characteristic feature of prokaryotic cells is the presence of a capsule, which is a protective layer outside the cell wall. This capsule helps the prokaryotic cell adhere to surfaces, evade the host immune system, and protect against desiccation. Choice A is incorrect because prokaryotic cells lack a nucleus. Choice C is incorrect as prokaryotic cells do not have membrane-bound organelles. Choice D is incorrect as prokaryotic cells can move using structures like flagella or pili.
2. Cells that line the inner or outer surfaces of organs or body cavities are often linked together by intimate physical connections. These connections are referred to as ______.
- A. Separate desmosomes
- B. Ronofilaments
- C. Tight junctions
- D. Fascia adherens
Correct answer: C
Rationale: The correct answer is C: Tight junctions. Tight junctions, also known as zonula occludens, are the intimate physical connections between cells that line the inner or outer surfaces of organs or body cavities. These junctions form a virtually impermeable barrier to fluid, creating a tight seal between the cells. This helps in maintaining the integrity and function of the tissue as well as regulating the movement of substances across the cell layer. Choice A, Separate desmosomes, are cell structures that provide strong adhesion between cells but do not create a barrier to fluid. Choice B, Ronofilaments, is not a term used to describe the connections between cells. Choice D, Fascia adherens, are another type of cell junction involved in cell adhesion, but they are different from tight junctions in terms of their structure and function.
3. What event occurs during telophase?
- A. The nuclear envelope disappears.
- B. Organelles double in number.
- C. Chromosomes separate.
- D. Two nuclei are formed.
Correct answer: D
Rationale: During telophase, the final stage of mitosis, the separated chromosomes reach opposite poles of the cell. At this stage, a new nuclear envelope forms around each set of chromosomes, creating two distinct nuclei. This marks the completion of cell division. Choices A, B, and C are incorrect because the disappearance of the nuclear envelope typically occurs during prophase, organelles do not double in number during telophase, and chromosomes separate during anaphase, not telophase.
4. How many different types of nucleotides are there in DNA?
- A. one
- B. two
- C. four
- D. eight
Correct answer: C
Rationale: The correct answer is 'C: four.' DNA is composed of four different types of nucleotides: adenine, thymine, guanine, and cytosine. These nucleotides pair up in specific combinations to form the genetic code. Choices 'A: one,' 'B: two,' and 'D: eight' are incorrect because DNA consists of a set of four distinct nucleotides, not one, two, or eight.
5. Which cellular structure is largely protective in function?
- A. Mitochondrion
- B. Vacuole
- C. Cell membrane
- D. Ribosome
Correct answer: C
Rationale: The correct answer is C: Cell membrane. The cell membrane, also known as the plasma membrane, is largely protective in function as it serves as a selectively permeable barrier that surrounds the cell, providing structural support and helping to maintain cell integrity. It regulates the movement of substances in and out of the cell, thus protecting the cell from harmful external factors while allowing essential nutrients to enter. Mitochondrion (choice A) is responsible for energy production, not primarily protective. Vacuole (choice B) is mainly involved in storage and transport. Ribosome (choice D) is involved in protein synthesis, not protective functions.
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