HESI A2
Biology HESI A2 Practice Test
1. 72 chromosomes undergo meiosis. How many chromosomes will be in each gamete?
- A. 18
- B. 36
- C. 72
- D. 144
Correct answer: A
Rationale: During meiosis, the number of chromosomes is halved in each gamete. Since 72 chromosomes undergo meiosis, each gamete will contain half of that number, which is 36 chromosomes. Therefore, the correct answer is 18 chromosomes in each gamete. Choice B (36 chromosomes) is incorrect because it represents the total number of chromosomes that undergo meiosis, not the number in each gamete. Choice C (72 chromosomes) is incorrect as it represents the initial number of chromosomes, not the number in each gamete after meiosis. Choice D (144 chromosomes) is incorrect as it doubles the initial number of chromosomes, which is not the outcome of meiosis.
2. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
3. Why are bacteria and blue-green algae often classified together?
- A. Both are gymnosperms.
- B. Both are prokaryotes.
- C. Both are autotrophs.
- D. Both are pathogens.
Correct answer: B
Rationale: Bacteria and blue-green algae (cyanobacteria) are often classified together because they are both prokaryotes. Prokaryotes are unicellular organisms that lack a membrane-bound nucleus and other membrane-bound organelles. This characteristic distinguishes them from eukaryotic organisms, which have these membrane-bound structures. Choice A is incorrect because gymnosperms are seed-producing plants with naked seeds, not bacteria or blue-green algae. Choice C is incorrect because being an autotroph (able to produce its own food) is not a reason for classifying them together. Choice D is incorrect because not all bacteria and blue-green algae are pathogens; many of them are beneficial or neutral to other organisms.
4. What is the typical result of mitosis in humans?
- A. two diploid cells
- B. two haploid cells
- C. four diploid cells
- D. four haploid cells
Correct answer: A
Rationale: The correct answer is A: two diploid cells. Mitosis is a type of cell division that results in two daughter cells, each having the same number of chromosomes as the parent cell. In humans, the typical result of mitosis is the formation of two diploid cells, not haploid or four cells. Choice B, two haploid cells, is incorrect because mitosis produces genetically identical diploid cells. Choices C and D, four diploid cells and four haploid cells, respectively, are incorrect as mitosis results in two daughter cells, not four.
5. What happens during the S phase of the cell cycle?
- A. Chromosomes are duplicated.
- B. Cell growth occurs.
- C. DNA is synthesized.
- D. DNA is destroyed.
Correct answer: A
Rationale: During the S phase of the cell cycle, chromosomes are duplicated. This is a critical step in cell division as each chromosome is replicated to ensure that the resulting daughter cells receive an identical set of genetic information. Choices B, C, and D are incorrect because cell growth primarily occurs in the G1 phase, DNA synthesis happens during the S phase, and DNA destruction does not occur during any phase of the cell cycle.
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