HESI A2
HESI A2 Practice Test Biology
1. Which of the following is a protein?
- A. cellulose
- B. hemoglobin
- C. estrogen
- D. ATP
Correct answer: B
Rationale: The correct answer is 'hemoglobin' because it is a protein that carries oxygen in the blood. Cellulose is a carbohydrate found in the cell walls of plants, not a protein. Estrogen is a hormone, not a protein. ATP (adenosine triphosphate) is a molecule that carries energy within cells, not a protein.
2. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
3. What is the role of tRNA during protein synthesis?
- A. Carries amino acids to the ribosome
- B. Links nucleotides together
- C. Copies DNA sequences
- D. Replicates genetic material
Correct answer: A
Rationale: During protein synthesis, tRNA plays the crucial role of carrying amino acids to the ribosome. This process ensures that the correct amino acids are brought to the ribosome according to the mRNA sequence. Choice B, linking nucleotides together, refers to the role of RNA polymerase in transcription, not tRNA. Choice C, copying DNA sequences, is the function of DNA polymerase during DNA replication, while choice D, replicating genetic material, is an overarching function of DNA replication, not specific to tRNA's role in protein synthesis.
4. Phenotype refers to the _ of an individual.
- A. Genetic makeup
- B. Actual physical appearance
- C. Recessive alleles
- D. None of the above
Correct answer: B
Rationale: Phenotype refers to the actual physical appearance and characteristics of an individual, which are determined by the interaction of both genetic makeup (genotype) and environmental factors. It includes visible traits such as height, eye color, and hair type. Choice A, genetic makeup, refers to the genotype, which is the genetic constitution of an organism. Choice C, recessive alleles, is a specific type of gene variant and does not encompass the entire concept of phenotype. Choice D, none of the above, is incorrect as phenotype does refer to the actual physical appearance of an individual.
5. How does an enzyme work on a chemical reaction that occurs in a substrate?
- A. An enzyme slows down the chemical reaction.
- B. An enzyme speeds up the chemical reaction.
- C. An enzyme has no effect on the chemical reaction.
- D. An enzyme stops most chemical reactions.
Correct answer: B
Rationale: Enzymes are biological catalysts that facilitate chemical reactions by lowering the activation energy required for the reaction to occur. This allows the reaction to proceed more quickly and efficiently. Enzymes do not change the overall outcome of the reaction, but they significantly increase the rate at which it takes place. Therefore, choice B, 'An enzyme speeds up the chemical reaction,' is the correct answer. Choices A, C, and D are incorrect because enzymes do not slow down, have no effect, or stop chemical reactions; instead, they accelerate the process by lowering the activation energy.
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