HESI A2
Biology HESI A2 Practice Test
1. Which of the following is not true about enzymes?
- A. They catalyze reactions
- B. They lower the activation energy needed
- C. They have an active site
- D. They are typically proteins
Correct answer: B
Rationale: Enzymes lower the activation energy needed for a reaction to occur, not raise it. By lowering the activation energy, enzymes facilitate reactions, making them occur more easily and rapidly. Choice A is correct as enzymes indeed catalyze reactions. Choice C is correct as enzymes have specific active sites where substrates bind. Choice D is correct as enzymes are commonly proteins, although some RNA molecules also exhibit catalytic properties.
2. In which phase of mitosis do new nuclear membranes form around sets of chromosomes?
- A. Prophase
- B. Anaphase
- C. Telophase
- D. Interphase
Correct answer: C
Rationale: The correct answer is C, Telophase. During telophase, the final phase of mitosis, new nuclear membranes form around sets of chromosomes at the opposite poles of the cell. This process marks the completion of nuclear division in mitosis. Choices A, B, and D are incorrect because in prophase, chromosomes condense but nuclear membranes are not formed; in anaphase, chromosomes separate and move to opposite poles but no new nuclear membranes are formed; and in interphase, the cell prepares for division but nuclear membranes are not forming around sets of chromosomes.
3. How is mitosis different from meiosis?
- A. Mitosis is the process by which body cells are formed.
- B. Meiosis creates cells with half the chromosomes of the parent cell.
- C. Telophase occurs in both mitosis and meiosis.
- D. Spermatogenesis and oogenesis occur via meiosis.
Correct answer: B
Rationale: Meiosis is the type of cell division that creates cells with half the number of chromosomes compared to the parent cell. This is essential for sexual reproduction as it ensures that when the sex cells (sperm and egg) combine during fertilization, the resulting offspring has the correct number of chromosomes. In contrast, mitosis results in two identical daughter cells with the same number of chromosomes as the parent cell. Choice A is incorrect because mitosis is responsible for the division of body cells, not sex cells. Choice C is incorrect because telophase is a phase that occurs in both mitosis and meiosis. Choice D is incorrect because spermatogenesis and oogenesis involve meiosis, not mitosis.
4. What process do cells in the tip of a plant’s root undergo to increase in number?
- A. Meiosis
- B. Cytokinesis
- C. Fractioning
- D. Mitosis
Correct answer: D
Rationale: Cells in the tip of a plant's root undergo the process of mitosis to increase in number. Mitosis is a type of cell division that results in two daughter cells with the same number of chromosomes as the parent cell. This process allows for growth and maintenance of tissues in plants by producing new cells through division. Choice A, Meiosis, is incorrect as meiosis is a type of cell division that reduces the number of chromosomes in cells to produce gametes. Choice B, Cytokinesis, is incorrect as it is the division of the cytoplasm following cell division. Choice C, Fractioning, is not a biological process related to cell division.
5. Which of the following shows how information is transformed to make a protein?
- A. DNA-RNA-protein
- B. gene-chromosome-protein
- C. ATP-amino acid-protein
- D. RNA-DNA-protein
Correct answer: A
Rationale: The correct sequence of events for protein synthesis is that DNA is transcribed into RNA, which is then translated into a protein. This process is known as the central dogma of molecular biology. In this sequence, DNA serves as the template for RNA synthesis (transcription), and the RNA serves as the template for protein synthesis (translation). Choice B is incorrect as genes are segments of DNA that code for proteins, and chromosomes are structures that contain DNA. Choice C is incorrect as ATP is an energy molecule and amino acids are the building blocks of proteins, but they are not directly involved in the synthesis process. Choice D is incorrect because RNA is first transcribed from DNA and then used as a template to produce proteins.
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