HESI A2
Biology HESI A2 Practice Test
1. A scientist needs 12 mL of a solution. They have a bottle with 12L in it. Do they have enough?
- A. Yes, they have exactly what they need
- B. Yes, they have more than what they need
- C. No, they do not have enough
- D. None of the above
Correct answer: B
Rationale: 1 liter has 1000 milliliters. To convert from milliliters to liters, the decimal point moves three places to the left. So, the bottle has 12000 mL of solution, which is a lot more than the required 12 mL. Therefore, the scientist has more than what they need. Choice A is incorrect as the bottle has more than the required amount. Choice C is incorrect as the bottle contains significantly more solution than needed. Choice D is incorrect as the scientist does have more than enough solution.
2. Which of the following is true of the Krebs cycle?
- A. It is a redox reaction involving proteins produced during glycolysis
- B. It is a redox reaction involving sugars produced during glycolysis
- C. Protons are passed along a gradient to produce ATP
- D. It is also known as the glycolic acid cycle
Correct answer: B
Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.
3. How many bones are included in the human skeletal system?
- A. 412
- B. 103
- C. Over 300
- D. 206
Correct answer: D
Rationale: There are 206 bones in the human skeletal system. This includes bones in the skull, spine, ribs, arms, legs, hands, and feet. The correct answer is 206 because that is the standard number of bones in an adult human body. Choices A, B, and C are incorrect as they do not reflect the accurate count of bones in the human skeletal system.
4. How many different types of nucleotides are there in DNA?
- A. one
- B. two
- C. four
- D. eight
Correct answer: C
Rationale: The correct answer is 'C: four.' DNA is composed of four different types of nucleotides: adenine, thymine, guanine, and cytosine. These nucleotides pair up in specific combinations to form the genetic code. Choices 'A: one,' 'B: two,' and 'D: eight' are incorrect because DNA consists of a set of four distinct nucleotides, not one, two, or eight.
5. Which structure might be described as a core of nucleic acid surrounded by a protein coat?
- A. RNA
- B. Virus
- C. Blue-green alga
- D. Saprophyte
Correct answer: B
Rationale: A virus can be described as a core of nucleic acid (either RNA or DNA) surrounded by a protein coat, known as a capsid. This structure distinguishes viruses from other microorganisms such as blue-green algae (Cyanobacteria), fungi known as saprophytes, or individual RNA molecules. Viruses depend on a host cell to replicate and are considered non-living entities due to their inability to carry out metabolic functions independently.
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