physical factors such as temperature and ph can alter enzyme activity because they have an effect on the enzymes
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HESI A2

Biology HESI A2 2024

1. Physical factors such as temperature and pH can alter enzyme activity because they have an effect on the enzyme's ___________.

Correct answer: B

Rationale: Physical factors such as temperature and pH can alter enzyme activity by affecting the enzyme's shape. Enzymes rely on their specific shapes to function properly and catalyze reactions. Any changes in temperature or pH can disrupt these shapes, causing the enzyme to become denatured and lose its functionality. Therefore, alterations in temperature and pH can impact enzyme activity by directly affecting their shapes. Choices A, C, and D are incorrect because while pH can affect acidity and chemical properties of the enzyme, and temperature can influence the enzyme-substrate interaction, the primary reason for enzyme activity alteration due to temperature and pH is the change in the enzyme's shape.

2. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?

Correct answer: B

Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.

3. Which organelle is responsible for detoxifying harmful substances in the cell?

Correct answer: C

Rationale: The correct answer is C, Peroxisomes. Peroxisomes are responsible for detoxifying harmful substances in the cell by breaking down fatty acids and producing hydrogen peroxide. This process helps protect the cell from damage caused by toxic substances. Choice A, Endoplasmic Reticulum, is involved in protein and lipid synthesis, not detoxification. Choice B, Lysosomes, contain enzymes for digestion and waste removal, not primarily detoxification. Choice D, Golgi Apparatus, is responsible for modifying, sorting, and packaging proteins for secretion, not detoxification.

4. Which organelle is involved in the synthesis of proteins?

Correct answer: B

Rationale: Ribosomes are the organelles involved in the synthesis of proteins. They are the cellular machinery responsible for translating mRNA into proteins, making them essential for cell function and structure. The other organelles listed, such as the Endoplasmic Reticulum, Lysosomes, and Vacuoles, have different functions unrelated to protein synthesis. The Endoplasmic Reticulum plays a role in protein processing and transport, Lysosomes are involved in digestion and waste removal, and Vacuoles are responsible for storage and maintaining cell turgor pressure.

5. Genes control heredity in man and other organisms. This gene is ___

Correct answer: A

Rationale: Genes are sections of DNA that contain instructions for building and operating living organisms. These sections of DNA contain the genetic information that is passed on from one generation to the next. Genes are composed of specific sequences of nucleotides within the DNA molecule. Therefore, genes are best described as segments of DNA. Choice A is correct. Choice B is incorrect because genes are not bead-like structures on chromosomes but specific sequences of DNA. Choice C is incorrect because genes are not protein molecules but rather sequences of nucleotides. Choice D is incorrect because genes are not segments of RNA but DNA.

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