HESI A2
Biology HESI A2 2024
1. Physical factors such as temperature and pH can alter enzyme activity because they have an effect on the enzyme's ___________.
- A. acidity
- B. shape
- C. chemistry
- D. substrate
Correct answer: B
Rationale: Physical factors such as temperature and pH can alter enzyme activity by affecting the enzyme's shape. Enzymes rely on their specific shapes to function properly and catalyze reactions. Any changes in temperature or pH can disrupt these shapes, causing the enzyme to become denatured and lose its functionality. Therefore, alterations in temperature and pH can impact enzyme activity by directly affecting their shapes. Choices A, C, and D are incorrect because while pH can affect acidity and chemical properties of the enzyme, and temperature can influence the enzyme-substrate interaction, the primary reason for enzyme activity alteration due to temperature and pH is the change in the enzyme's shape.
2. How many pairs of chromosomes do all humans have?
- A. 24 pairs
- B. 23 pairs
- C. 22 pairs
- D. 20 pairs
Correct answer: B
Rationale: All humans have 23 pairs of chromosomes, totaling 46 chromosomes. Choice A is incorrect because humans do not have 24 pairs. Choice C is incorrect as humans have 23 pairs, not 22 pairs. Choice D is incorrect as humans have 23 pairs of chromosomes, not 20 pairs.
3. Ocean waves may tear sponges into pieces, each of which may grow into a new sponge. What is this form of reproduction called?
- A. Budding
- B. Vegetative propagation
- C. Binary fission
- D. Fragmentation
Correct answer: D
Rationale: Fragmentation is the form of asexual reproduction where an organism breaks into fragments, and each fragment can grow into a new individual. In the case of sponges being torn into pieces by ocean waves, each piece has the potential to develop into a new sponge, making fragmentation the correct answer in this scenario. Budding is a form of asexual reproduction where a new organism develops as an outgrowth from the parent organism. Vegetative propagation involves the growth of new individuals from plant parts like stems or roots. Binary fission is a method of reproduction seen in some single-celled organisms where one cell divides into two identical cells.
4. Cells that line the inner or outer surfaces of organs or body cavities are often linked together by intimate physical connections. These connections are referred to as ______.
- A. Separate desmosomes
- B. Ronofilaments
- C. Tight junctions
- D. Fascia adherens
Correct answer: C
Rationale: The correct answer is C: Tight junctions. Tight junctions, also known as zonula occludens, are the intimate physical connections between cells that line the inner or outer surfaces of organs or body cavities. These junctions form a virtually impermeable barrier to fluid, creating a tight seal between the cells. This helps in maintaining the integrity and function of the tissue as well as regulating the movement of substances across the cell layer. Choice A, Separate desmosomes, are cell structures that provide strong adhesion between cells but do not create a barrier to fluid. Choice B, Ronofilaments, is not a term used to describe the connections between cells. Choice D, Fascia adherens, are another type of cell junction involved in cell adhesion, but they are different from tight junctions in terms of their structure and function.
5. A child is sick. They have a body temperature that exceeds 37ºC. The body senses this and begins to sweat in order to lower the temperature. What is this an example of?
- A. Positive feedback loop
- B. Negative feedback loop
- C. Both
- D. None of the above
Correct answer: B
Rationale: This is an example of a negative feedback loop. In a negative feedback loop, the body's response (sweating) works to counteract the initial stimulus of a high body temperature by cooling the body down. The goal is to return the body to homeostasis, maintaining a stable internal environment. Positive feedback loops amplify the initial stimulus rather than counteracting it, which is not the case here. Therefore, choices A and C are incorrect. Choice D is also incorrect as the situation described fits the characteristics of a negative feedback loop.
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