HESI A2
Biology HESI A2 2024
1. Physical factors such as temperature and pH can alter enzyme activity because they have an effect on the enzyme's ___________.
- A. acidity
- B. shape
- C. chemistry
- D. substrate
Correct answer: B
Rationale: Physical factors such as temperature and pH can alter enzyme activity by affecting the enzyme's shape. Enzymes rely on their specific shapes to function properly and catalyze reactions. Any changes in temperature or pH can disrupt these shapes, causing the enzyme to become denatured and lose its functionality. Therefore, alterations in temperature and pH can impact enzyme activity by directly affecting their shapes. Choices A, C, and D are incorrect because while pH can affect acidity and chemical properties of the enzyme, and temperature can influence the enzyme-substrate interaction, the primary reason for enzyme activity alteration due to temperature and pH is the change in the enzyme's shape.
2. Which of the following molecules is an important component of the plasma membrane?
- A. Phospholipids
- B. Steroids
- C. Sugars
- D. Amino acids
Correct answer: A
Rationale: Phospholipids are indeed a crucial component of the plasma membrane. They have a unique structure with hydrophilic heads and hydrophobic tails, which allows them to form the lipid bilayer of the membrane. Steroids, sugars, and amino acids are not primary components of the plasma membrane. Steroids are a different type of lipid, sugars are often found in glycoproteins on the membrane surface, and amino acids are the building blocks of proteins, some of which are membrane proteins, but not the membrane itself.
3. Which is not a product of the Krebs cycle?
- A. ATP
- B. Carbon dioxide
- C. Glucose
- D. NADH
Correct answer: C
Rationale: Glucose is not a direct product of the Krebs cycle. Glucose is a starting molecule that undergoes glycolysis outside the mitochondria to produce pyruvate, which then enters the mitochondrial matrix to participate in the Krebs cycle. The Krebs cycle primarily generates ATP, carbon dioxide, and NADH as products. Choices A, B, and D are all products of the Krebs cycle, making them incorrect answers.
4. What event occurs during telophase?
- A. The nuclear envelope disappears.
- B. Organelles double in number.
- C. Chromosomes separate.
- D. Two nuclei are formed.
Correct answer: D
Rationale: During telophase, the final stage of mitosis, the separated chromosomes reach opposite poles of the cell. At this stage, a new nuclear envelope forms around each set of chromosomes, creating two distinct nuclei. This marks the completion of cell division. Choices A, B, and C are incorrect because the disappearance of the nuclear envelope typically occurs during prophase, organelles do not double in number during telophase, and chromosomes separate during anaphase, not telophase.
5. What type of tissue is fat?
- A. Connective
- B. Muscle
- C. Nervous
- D. Epithelial
Correct answer: A
Rationale: Fat is a type of loose connective tissue known as adipose tissue. Adipose tissue primarily functions to store energy and provide cushioning and insulation for organs. While muscle tissue is responsible for movement, nervous tissue transmits nerve impulses, and epithelial tissue covers and protects body surfaces, fat specifically falls under the category of connective tissue.
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