HESI A2
Biology HESI A2 2024
1. How is mitosis different from meiosis?
- A. Mitosis is the process by which body cells are formed.
- B. Meiosis creates cells with half the chromosomes of the parent cell.
- C. Telophase occurs in both mitosis and meiosis.
- D. Spermatogenesis and oogenesis occur via meiosis.
Correct answer: B
Rationale: Meiosis is the type of cell division that creates cells with half the number of chromosomes compared to the parent cell. This is essential for sexual reproduction as it ensures that when the sex cells (sperm and egg) combine during fertilization, the resulting offspring has the correct number of chromosomes. In contrast, mitosis results in two identical daughter cells with the same number of chromosomes as the parent cell. Choice A is incorrect because mitosis is responsible for the division of body cells, not sex cells. Choice C is incorrect because telophase is a phase that occurs in both mitosis and meiosis. Choice D is incorrect because spermatogenesis and oogenesis involve meiosis, not mitosis.
2. A cell is in a solution in which the concentration of solutes is higher inside the cell than outside the cell. What would you expect to happen to the cell?
- A. It will swell and possibly burst.
- B. It will shrivel and shrink.
- C. It will maintain its current size.
- D. It will grow a supportive cell wall.
Correct answer: A
Rationale: When a cell is in a solution where the concentration of solutes is higher inside the cell than outside, it is in a hypertonic environment. In this situation, water will move into the cell in an attempt to equalize the concentration of solutes on both sides of the cell membrane through the process of osmosis. As a result, the cell will swell as it takes in more water, potentially leading to bursting or cell lysis. Choice B is incorrect because a cell in a hypertonic solution will not shrivel and shrink due to water moving into the cell. Choice C is incorrect because the cell will not maintain its current size; it will swell. Choice D is incorrect because growing a supportive cell wall is not the immediate response to being in a hypertonic environment.
3. Which component is not found in the nucleotide of DNA?
- A. Simple sugar
- B. Nitrogen base
- C. Phosphate group
- D. Citric acid
Correct answer: D
Rationale: Citric acid is not found in the nucleotide of DNA. A DNA nucleotide is composed of a simple sugar (deoxyribose), a nitrogen base (adenine, thymine, cytosine, or guanine), and a phosphate group. Citric acid is not part of DNA nucleotides; instead, it is involved in the citric acid cycle of cellular respiration. Choices A, B, and C are essential components of DNA nucleotides, making them incorrect answers.
4. Which statement is true of enzymes?
- A. They are made from lipids.
- B. They are made from proteins.
- C. They form double chains of DNA.
- D. They bind with catalysts.
Correct answer: B
Rationale: The correct answer is B: Enzymes are made from proteins. Enzymes are biological molecules that act as catalysts to speed up chemical reactions in living organisms. While the majority of enzymes are proteins, a few are made from RNA. The statement that enzymes are made from lipids (choice A) is incorrect. Enzymes do not form double chains of DNA (choice C) as their primary function is not related to DNA structure. Additionally, enzymes themselves do not bind with catalysts (choice D); instead, they act as catalysts to facilitate reactions.
5. How should a researcher test the hypothesis that eating chocolate leads to acne in teenagers?
- A. Take 100 teenagers and feed each one a different amount of chocolate daily for 60 days; then test for acne.
- B. Take 100 teenagers and feed 50 two bars of chocolate daily for 60 days while the other 50 eat no chocolate; then test for acne.
- C. Take 1 teenager and feed him or her two bars of chocolate for 30 days and no chocolate for 30 days; then test for acne.
- D. Take 100 teenagers and feed them no chocolate for 30 days and two bars of chocolate apiece for 30 days; then test for acne.
Correct answer: B
Rationale: Option B is the correct approach to test the hypothesis that eating chocolate leads to acne in teenagers. This method involves having a control group (50 teenagers not consuming chocolate) and an experimental group (50 teenagers consuming two bars of chocolate daily), which allows for comparison. By having two distinct groups, researchers can assess the impact of chocolate consumption on acne development. Option A lacks a control group for comparison, making it harder to attribute any observed effects specifically to chocolate consumption. Option C only involves a single subject, which limits the generalizability of the results. Option D, where all teenagers experience both conditions, does not allow for a direct comparison between chocolate consumption and acne development, as all subjects are exposed to both conditions.
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