HESI A2
Biology HESI A2 2024
1. How is mitosis different from meiosis?
- A. Mitosis is the process by which body cells are formed.
- B. Meiosis creates cells with half the chromosomes of the parent cell.
- C. Telophase occurs in both mitosis and meiosis.
- D. Spermatogenesis and oogenesis occur via meiosis.
Correct answer: B
Rationale: Meiosis is the type of cell division that creates cells with half the number of chromosomes compared to the parent cell. This is essential for sexual reproduction as it ensures that when the sex cells (sperm and egg) combine during fertilization, the resulting offspring has the correct number of chromosomes. In contrast, mitosis results in two identical daughter cells with the same number of chromosomes as the parent cell. Choice A is incorrect because mitosis is responsible for the division of body cells, not sex cells. Choice C is incorrect because telophase is a phase that occurs in both mitosis and meiosis. Choice D is incorrect because spermatogenesis and oogenesis involve meiosis, not mitosis.
2. What is DNA made of?
- A. Proteins
- B. Nucleotides
- C. Lipids
- D. Carbohydrates
Correct answer: B
Rationale: DNA is made up of nucleotides, which are the building blocks of genetic material. Choice A (Proteins) is incorrect because while proteins play a crucial role in the body, they are not the building blocks of DNA. Choice C (Lipids) and Choice D (Carbohydrates) are also incorrect as they are not the primary components of DNA.
3. What organelle pushes water out of the cell?
- A. Lysosomes
- B. Vacuoles (contractile)
- C. Mitochondria
- D. Nucleus
Correct answer: B
Rationale: The correct answer is B: Vacuoles (contractile). Vacuoles (contractile) are responsible for expelling excess water out of the cell. Lysosomes are involved in the digestion and removal of waste materials, mitochondria are the powerhouse of the cell involved in energy production, and the nucleus contains the cell's genetic material but does not play a role in pushing water out of the cell.
4. What is the main function of the ribosomes in the cell?
- A. DNA Replication
- B. Protein Synthesis
- C. Lipid Breakdown
- D. Cell Division
Correct answer: B
Rationale: The correct answer is B: Protein Synthesis. Ribosomes are cellular organelles responsible for synthesizing proteins. This process is crucial for various cellular functions. Choice A, DNA Replication, is incorrect as ribosomes are not involved in this process. Choice C, Lipid Breakdown, is also incorrect as ribosomes do not play a role in lipid metabolism. Choice D, Cell Division, is incorrect as ribosomes are not directly involved in the process of cell division.
5. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
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