HESI A2
Biology HESI A2 2024
1. In an example of a male with hemophilia and a female carrier, what ratio of the offspring is predicted to have the disease?
- A. 0 female : 2 males
- B. 1 female : 0 males
- C. 1 female : 2 males
- D. 2 females : 1 male
Correct answer: C
Rationale: In this scenario, the male offspring will inherit the hemophilia trait from their mother due to the sex-linked inheritance pattern. The female offspring will inherit one X chromosome from their mother, becoming carriers of hemophilia. Therefore, the predicted ratio of offspring with the disease would be 1 female as a carrier and 2 males with hemophilia. Choice A is incorrect because there would be male offspring with the disease. Choice B is incorrect as there would be male offspring with hemophilia. Choice D is incorrect as it does not reflect the inheritance pattern of hemophilia.
2. The cell membrane consists of a bilayer of phospholipids with proteins, cholesterol, and glycoproteins. What does this bilayer create?
- A. Impermeable
- B. Permeable
- C. Selectively permeable
- D. Selectively impermeable
Correct answer: C
Rationale: The correct answer is 'Selectively permeable.' The cell membrane's bilayer structure allows it to be selectively permeable, meaning it can control the passage of substances. This property enables the membrane to regulate the entry and exit of specific molecules, ions, and other substances. Choice A, 'Impermeable,' is incorrect as the cell membrane is not completely impermeable and does allow certain substances to pass through. Choice B, 'Permeable,' is also incorrect as it does not address the selective nature of the membrane. Choice D, 'Selectively impermeable,' is a contradictory term and does not accurately describe the cell membrane's function.
3. Which two bases are purines?
- A. Adenine (A)
- B. Cytosine (C)
- C. Thymine (T)
- D. Guanine (G)
Correct answer: A
Rationale: Adenine (A) and guanine (G) are the two bases that are purines. Purines are characterized by a double-ring structure containing two carbon rings, distinguishing them from pyrimidines. Adenine and guanine are purines because they possess this unique double-ring structure. Therefore, choices A and D, adenine and guanine, respectively, are the correct answers. Choices B and C, cytosine and thymine, are pyrimidines and do not exhibit the double-ring structure characteristic of purines.
4. What is the process by which cells divide to form two identical daughter cells?
- A. Mitosis
- B. Meiosis
- C. Binary Fission
- D. Cellular Division
Correct answer: A
Rationale: The correct answer is A, Mitosis. Mitosis is the process in which a cell divides to form two identical daughter cells. Choice B, Meiosis, is a type of cell division that results in four non-identical daughter cells with half the number of chromosomes. Choice C, Binary Fission, is a form of asexual reproduction used by prokaryotic organisms. Choice D, Cellular Division, is a general term that encompasses various processes of cell division, but specifically, mitosis refers to the division resulting in two identical daughter cells.
5. Why are bacteria and blue-green algae often classified together?
- A. Both are gymnosperms.
- B. Both are prokaryotes.
- C. Both are autotrophs.
- D. Both are pathogens.
Correct answer: B
Rationale: Bacteria and blue-green algae (cyanobacteria) are often classified together because they are both prokaryotes. Prokaryotes are unicellular organisms that lack a membrane-bound nucleus and other membrane-bound organelles. This characteristic distinguishes them from eukaryotic organisms, which have these membrane-bound structures. Choice A is incorrect because gymnosperms are seed-producing plants with naked seeds, not bacteria or blue-green algae. Choice C is incorrect because being an autotroph (able to produce its own food) is not a reason for classifying them together. Choice D is incorrect because not all bacteria and blue-green algae are pathogens; many of them are beneficial or neutral to other organisms.
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