hemophilia is a sex linked trait carried on the x chromosome in an example of a male with hemophilia and a female carrier what ratio of the offspring
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HESI A2

Biology HESI A2 2024

1. In an example of a male with hemophilia and a female carrier, what ratio of the offspring is predicted to have the disease?

Correct answer: C

Rationale: In this scenario, the male offspring will inherit the hemophilia trait from their mother due to the sex-linked inheritance pattern. The female offspring will inherit one X chromosome from their mother, becoming carriers of hemophilia. Therefore, the predicted ratio of offspring with the disease would be 1 female as a carrier and 2 males with hemophilia. Choice A is incorrect because there would be male offspring with the disease. Choice B is incorrect as there would be male offspring with hemophilia. Choice D is incorrect as it does not reflect the inheritance pattern of hemophilia.

2. How many different types of nucleotides are there in DNA?

Correct answer: C

Rationale: The correct answer is 'C: four.' DNA is composed of four different types of nucleotides: adenine, thymine, guanine, and cytosine. These nucleotides pair up in specific combinations to form the genetic code. Choices 'A: one,' 'B: two,' and 'D: eight' are incorrect because DNA consists of a set of four distinct nucleotides, not one, two, or eight.

3. RNA is made from DNA through a process called ___________.

Correct answer: A

Rationale: RNA is made from DNA through a process called transcription. During transcription, an enzyme called RNA polymerase reads the DNA template and synthesizes a complementary RNA molecule. This process is essential for gene expression and allows the information encoded in DNA to be converted into functional RNA molecules. Choice B, 'synthesis,' is incorrect as it is a general term and does not specifically describe the process of RNA formation from DNA. Choice C, 'translation,' is incorrect as it refers to the process where the mRNA is used to assemble amino acids during protein synthesis, not the conversion of DNA to RNA. Choice D, 'replication,' is incorrect as it is the process of making an identical copy of DNA, not converting DNA into RNA.

4. What kind of bond connects sugar and phosphate in DNA?

Correct answer: C

Rationale: Sugar and phosphate are indeed connected by covalent bonds in DNA. Covalent bonds involve the sharing of electrons between atoms, which is essential for forming the backbone of the DNA molecule. Hydrogen bonds (Choice A) are important in holding the nitrogenous bases together in the DNA double helix but do not connect sugar and phosphate. Ionic bonds (Choice B) involve the transfer of electrons between atoms and are not the primary bond connecting sugar and phosphate in DNA. 'Overt' (Choice D) is not a type of chemical bond and is an incorrect distractor.

5. Which of these molecules contains glucose?

Correct answer: D

Rationale: Glucose is a type of simple sugar and is classified as a carbohydrate. It is commonly found in various carbohydrate-containing foods such as fruits, vegetables, grains, and sugary snacks. Therefore, the molecule containing glucose would be a carbohydrate, making choice D the correct answer. Proteins (choice A) are made up of amino acids, lipids (choice B) are fats, and nucleic acids (choice C) are DNA and RNA, none of which contain glucose.

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