HESI A2
Biology HESI A2 2024
1. In an example of a male with hemophilia and a female carrier, what ratio of the offspring is predicted to have the disease?
- A. 0 female : 2 males
- B. 1 female : 0 males
- C. 1 female : 2 males
- D. 2 females : 1 male
Correct answer: C
Rationale: In this scenario, the male offspring will inherit the hemophilia trait from their mother due to the sex-linked inheritance pattern. The female offspring will inherit one X chromosome from their mother, becoming carriers of hemophilia. Therefore, the predicted ratio of offspring with the disease would be 1 female as a carrier and 2 males with hemophilia. Choice A is incorrect because there would be male offspring with the disease. Choice B is incorrect as there would be male offspring with hemophilia. Choice D is incorrect as it does not reflect the inheritance pattern of hemophilia.
2. Why do cells need to use exocytosis?
- A. To obtain energy
- B. To defend against invaders
- C. To remove waste products
- D. To undergo division
Correct answer: C
Rationale: Cells need to use exocytosis to remove waste products from the cell. Exocytosis is a process where cells release molecules or substances outside the cell by fusing vesicles with the cell membrane. This process is crucial for maintaining cellular homeostasis by efficiently eliminating waste materials. Choices A, B, and D are incorrect because exocytosis is specifically involved in the expulsion of molecules, not for obtaining energy, defending against invaders, or cell division.
3. A cell from heart muscle would more than likely contain an unusually high proportion of which of the following?
- A. lysosomes
- B. mitochondria
- C. mRNA
- D. ribosomes
Correct answer: B
Rationale: A cell from heart muscle would more than likely contain an unusually high proportion of mitochondria because the heart muscle requires a significant amount of energy to function properly. Mitochondria are the powerhouse of the cell and are responsible for producing energy in the form of ATP through cellular respiration. Therefore, to meet the high energy demands of the heart muscle, it would need a higher concentration of mitochondria compared to other cell types. Choices A, C, and D are incorrect because while lysosomes, mRNA, and ribosomes are essential components of a cell, they do not play as direct a role in meeting the high energy demands of heart muscle as mitochondria do.
4. RNA is made from DNA through a process called ___________.
- A. transcription
- B. synthesis
- C. translation
- D. replication
Correct answer: A
Rationale: RNA is made from DNA through a process called transcription. During transcription, an enzyme called RNA polymerase reads the DNA template and synthesizes a complementary RNA molecule. This process is essential for gene expression and allows the information encoded in DNA to be converted into functional RNA molecules. Choice B, 'synthesis,' is incorrect as it is a general term and does not specifically describe the process of RNA formation from DNA. Choice C, 'translation,' is incorrect as it refers to the process where the mRNA is used to assemble amino acids during protein synthesis, not the conversion of DNA to RNA. Choice D, 'replication,' is incorrect as it is the process of making an identical copy of DNA, not converting DNA into RNA.
5. Anaerobic respiration happens in _ because _ .
- A. Animals; they need energy
- B. Plants; they use sunlight
- C. Bacteria; they live in environments with low oxygen
- D. None of the above
Correct answer: C
Rationale: Anaerobic respiration happens in bacteria because they live in environments with low oxygen. Bacteria, unlike animals and plants, do not have easy access to oxygen for aerobic respiration and must find alternative ways to produce energy to survive. This makes anaerobic respiration essential for their metabolic processes. Choice A is incorrect because although animals need energy, they generally rely on aerobic respiration when oxygen is available. Choice B is incorrect because plants primarily perform photosynthesis using sunlight to produce energy. Choice D is incorrect as anaerobic respiration does occur in specific organisms like bacteria when oxygen is scarce.
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