HESI A2
HESI A2 Biology 2024
1. In an example of a male with hemophilia and a female carrier, what percentage of the offspring is predicted to be carriers only?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: C
Rationale: In this scenario, the male offspring will inherit the X chromosome with the hemophilia gene from the mother, as males have one X chromosome inherited from their mother. The female offspring will inherit one normal X chromosome from the father and one X chromosome with the hemophilia gene from the mother, making them carriers of the hemophilia trait. Therefore, 50% of the offspring will be carriers only. Option A (0%) is incorrect as female offspring will inherit the X chromosome with the hemophilia gene from the mother. Option B (25%) is incorrect as the female offspring will not be unaffected. Option D (100%) is incorrect as not all offspring will be carriers, only the female offspring.
2. Which of the following is a protein?
- A. cellulose
- B. hemoglobin
- C. estrogen
- D. ATP
Correct answer: B
Rationale: The correct answer is 'hemoglobin' because it is a protein that carries oxygen in the blood. Cellulose is a carbohydrate found in the cell walls of plants, not a protein. Estrogen is a hormone, not a protein. ATP (adenosine triphosphate) is a molecule that carries energy within cells, not a protein.
3. Two organisms live in a relationship from which both benefit. What is this called?
- A. Mutualism
- B. Parasitism
- C. Commensalism
- D. Competition
Correct answer: A
Rationale: Mutualism is a type of symbiotic relationship between two organisms in which both parties benefit from the association. It is a mutually beneficial interaction where both organisms gain something valuable, such as food, protection, or some other resource. This contrasts with parasitism, where one organism benefits at the expense of the other, commensalism, where one organism benefits while the other is unaffected, and competition, where both organisms are negatively affected by their interaction.
4. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
5. Which organelle is responsible for making proteins?
- A. Ribosome
- B. Chloroplast
- C. Lysosome
- D. Mitochondrion
Correct answer: A
Rationale: Ribosomes are the organelles responsible for protein synthesis within the cell. They are the sites where amino acids are linked together to form proteins based on the instructions carried by mRNA (messenger RNA). Ribosomes can be found free-floating in the cytoplasm or attached to the endoplasmic reticulum, and they play a crucial role in translating genetic information into proteins. Chloroplasts are responsible for photosynthesis, lysosomes are involved in digestion and waste removal, and mitochondria are known as the powerhouse of the cell responsible for energy production through cellular respiration. Therefore, the ribosome is the correct organelle responsible for making proteins.
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