HESI A2
HESI A2 Biology 2024
1. In an example of a male with hemophilia and a female carrier, what percentage of the offspring is predicted to be carriers only?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: C
Rationale: In this scenario, the male offspring will inherit the X chromosome with the hemophilia gene from the mother, as males have one X chromosome inherited from their mother. The female offspring will inherit one normal X chromosome from the father and one X chromosome with the hemophilia gene from the mother, making them carriers of the hemophilia trait. Therefore, 50% of the offspring will be carriers only. Option A (0%) is incorrect as female offspring will inherit the X chromosome with the hemophilia gene from the mother. Option B (25%) is incorrect as the female offspring will not be unaffected. Option D (100%) is incorrect as not all offspring will be carriers, only the female offspring.
2. The phases of mitosis include:
- A. Prophase, interphase, metaphase, anaphase, and telophase
- B. Prophase, prophase, metaphase, anaphase, and cytokinesis
- C. Prophase, prometaphase, metaphase, anaphase, and telophase
- D. Prophase, interphase, prophase, anaphase, and telophase
Correct answer: C
Rationale: The correct phases of mitosis are prophase, prometaphase, metaphase, anaphase, and telophase. Prophase is the first phase where chromatin condenses into chromosomes, the nuclear envelope breaks down, and the mitotic spindle forms. Prometaphase follows prophase, involving the full disintegration of the nuclear envelope and the attachment of spindle fibers to the kinetochores of the chromosomes. Metaphase is where chromosomes align along the metaphase plate. Anaphase is the phase where sister chromatids separate and move towards opposite poles. Telophase marks the final stage of mitosis, involving the decondensation of chromosomes and the reformation of the nuclear envelope. Choice A is incorrect because it includes interphase, which is not a phase of mitosis. Choice B is incorrect as it repeats prophase, which is the initial phase. Choice D is incorrect because it includes interphase and repeats prophase.
3. Where is the genetic code for each person stored?
- A. RNA
- B. DNA
- C. Nucleus
- D. Chromosomes
Correct answer: B
Rationale: The genetic code for each person is stored in DNA. DNA carries all the hereditary information, including unique traits and characteristics. RNA (Choice A) is involved in protein synthesis but does not hold the complete genetic code. The nucleus (Choice C) is a cellular organelle that houses the DNA, but it is not the genetic code itself. Chromosomes (Choice D) are structures made of DNA and proteins, but the genetic code is specifically encoded in the DNA molecule.
4. Which of these is not an example of a lipid?
- A. Butter
- B. Wax
- C. Canola oil
- D. Honey
Correct answer: D
Rationale: Honey is not an example of a lipid because lipids are fat-related molecules that are insoluble in water, while honey is a natural sweet substance made by bees and primarily consists of sugars such as glucose and fructose. Butter, wax, and canola oil are examples of lipids as they are all composed of fat-related molecules that do not dissolve in water.
5. Why can animal cells use a contractile ring but plant cells cannot?
- A. Plant cells can use both methods to divide
- B. Animal cells divide faster, requiring them to pinch apart
- C. Plant cells are too rigid to use a contractile ring
- D. N/A
Correct answer: C
Rationale: Plant cells have a rigid cell wall surrounding them, which prevents them from using a contractile ring for cell division. The rigid cell wall requires plant cells to form a cell plate during cell division instead of pinching apart like animal cells with a contractile ring. Choice A is incorrect because plant cells cannot use a contractile ring due to their rigid cell wall. Choice B is incorrect as the speed of cell division is not the primary reason for the difference in cell division mechanisms between plant and animal cells. Choice D is not applicable as plant cells indeed have a specific limitation in using a contractile ring for cell division.
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