HESI A2
HESI A2 Biology Practice Test
1. Which of the following types of hormones can diffuse through the cell membrane to bind to receptors inside the cell and stimulate a chemical response to a target cell?
- A. fat-soluble hormones
- B. amino acid derivatives
- C. hydrophilic hormones
- D. water-soluble hormones
Correct answer: A
Rationale: The correct answer is A: fat-soluble hormones. Fat-soluble hormones are able to diffuse through the cell membrane to bind to receptors inside the cell. This is because they are lipophilic, allowing them to cross the lipid bilayer easily. Once inside the cell, fat-soluble hormones can directly affect gene expression or cell function. Choice B, amino acid derivatives, and choice C, hydrophilic hormones, are not able to diffuse through the cell membrane as they are not lipophilic. Therefore, they cannot bind to receptors inside the cell. Choice D, water-soluble hormones, also cannot diffuse through the cell membrane as it is hydrophilic, making it unable to reach receptors inside the cell.
2. Whose energy efficiency is greater?
- A. Herbivore
- B. Carnivore
- C. Omnivore
- D. Decomposer
Correct answer: D
Rationale: Decomposers have the greatest efficiency of energy among the given options. Decomposers break down organic matter, such as dead plants and animals, into simpler substances through the process of decomposition. This breakdown process results in the release of nutrients back into the ecosystem, making energy more readily available for other organisms to use. In contrast, herbivores, carnivores, and omnivores all derive their energy from the consumption of other living organisms, making their energy efficiency lower than that of decomposers. Herbivores consume plants for energy, which involves energy loss due to inefficiencies in converting plant matter into usable energy. Carnivores consume herbivores or other carnivores, leading to further energy loss through each trophic level. Omnivores consume both plant and animal matter, but their energy efficiency is still lower than decomposers because of the energy loss associated with consuming living organisms. Decomposers play a crucial role in recycling nutrients and energy in ecosystems, making them highly efficient in the utilization of energy.
3. Which of the following are considered the most important molecules in biology?
- A. Carbohydrates, lipids, protein, and nucleic acids
- B. Carbohydrates, lipids, protein, and calcium
- C. Carbohydrates, lipids, protein, and sulfur
- D. Carbohydrates, lipids, protein, and iron
Correct answer: A
Rationale: The correct answer is A: Carbohydrates, lipids, protein, and nucleic acids are considered the most important molecules in biology. Carbohydrates are essential for providing energy, lipids for storing energy and forming cell membranes, proteins for various structural and functional roles, and nucleic acids (DNA and RNA) for storing genetic information. Choices B, C, and D are incorrect because while carbohydrates, lipids, and proteins are crucial biomolecules, calcium, sulfur, and iron are not considered among the most important molecules in biology.
4. The apical side of an epithelial cell:
- A. Is exposed to fluid or air
- B. Is on the bottom side of the cell
- C. Does not allow any substances to pass through
- D. None of the above
Correct answer: A
Rationale: The apical side of an epithelial cell is the top side, which is typically exposed to fluids, air, or the inside of an organ. This side allows substances to pass through it, facilitating the absorption, secretion, or excretion of various substances. Choice B is incorrect as the apical side is not on the bottom but the top side. Choice C is incorrect as the apical side does allow substances to pass through. Choice D is incorrect as there are characteristics associated with the apical side.
5. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
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