HESI A2
Biology HESI A2 Practice Test
1. Which organelle is responsible for making proteins?
- A. Ribosome
- B. Chloroplast
- C. Lysosome
- D. Mitochondrion
Correct answer: A
Rationale: Ribosomes are the organelles responsible for protein synthesis within the cell. They are the sites where amino acids are linked together to form proteins based on the instructions carried by mRNA (messenger RNA). Ribosomes can be found free-floating in the cytoplasm or attached to the endoplasmic reticulum, and they play a crucial role in translating genetic information into proteins. Chloroplasts are responsible for photosynthesis, lysosomes are involved in digestion and waste removal, and mitochondria are known as the powerhouse of the cell responsible for energy production through cellular respiration. Therefore, the ribosome is the correct organelle responsible for making proteins.
2. Patient A, who weighs 68 kilograms, steps onto a scale 20 times. The scale consistently weighs Patient A as 75 kilograms. What is true of the measurement?
- A. It is valid, but not reliable.
- B. It is reliable, but not valid.
- C. It is both valid and reliable.
- D. It is neither reliable nor valid.
Correct answer: B
Rationale: The correct answer is B: 'It is reliable, but not valid.' The measurement is reliable because it consistently provides the same result (75 kg). However, it is not valid because it does not accurately reflect the true weight of Patient A (68 kg). Choice A is incorrect because if the scale consistently shows the same weight (75 kg), it is reliable. Choice C is incorrect because although the scale is consistent, the measurement does not reflect the true weight, making it not valid. Choice D is incorrect as the measurement is reliable but lacks validity.
3. Which of these molecules contains glucose?
- A. Proteins
- B. Lipids
- C. Nucleic acids
- D. Carbohydrates
Correct answer: D
Rationale: Glucose is a type of simple sugar and is classified as a carbohydrate. It is commonly found in various carbohydrate-containing foods such as fruits, vegetables, grains, and sugary snacks. Therefore, the molecule containing glucose would be a carbohydrate, making choice D the correct answer. Proteins (choice A) are made up of amino acids, lipids (choice B) are fats, and nucleic acids (choice C) are DNA and RNA, none of which contain glucose.
4. Which of the following is not true about enzymes?
- A. They catalyze reactions
- B. They lower the activation energy needed
- C. They have an active site
- D. They are typically proteins
Correct answer: B
Rationale: Enzymes lower the activation energy needed for a reaction to occur, not raise it. By lowering the activation energy, enzymes facilitate reactions, making them occur more easily and rapidly. Choice A is correct as enzymes indeed catalyze reactions. Choice C is correct as enzymes have specific active sites where substrates bind. Choice D is correct as enzymes are commonly proteins, although some RNA molecules also exhibit catalytic properties.
5. Why does cellular respiration happen?
- A. Cells can copy DNA
- B. Cells can breathe
- C. Cells can convert nutrients to energy
- D. Cells can divide
Correct answer: C
Rationale: Cellular respiration is the process through which cells break down nutrients such as glucose to produce ATP (adenosine triphosphate), the energy currency of the cell. This process allows cells to extract energy from food molecules and use it for various cellular activities and functions. Choices A, B, and D are incorrect because cellular respiration is specifically about converting nutrients to energy, not about DNA copying, breathing, or cell division.
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