HESI A2
HESI A2 Practice Test Biology
1. During which phase is the chromosome number reduced from diploid to haploid?
- A. S phase
- B. interphase
- C. mitosis
- D. meiosis I
Correct answer: D
Rationale: The correct answer is 'meiosis I.' During meiosis I, the chromosome number is reduced from diploid to haploid through two rounds of division. Choice A ('S phase') is incorrect as the S phase is part of the cell cycle where DNA is replicated. Choice B ('interphase') is also incorrect as interphase is the phase where the cell prepares for division. Choice C ('mitosis') is incorrect as mitosis is a process where a diploid cell divides to produce two identical diploid daughter cells, maintaining the chromosome number.
2. Which, if any, of the following statements are true?
- A. Water boils at approximately 100°C (212°F) at standard atmospheric pressure
- B. The boiling point is the temperature at which the vapor pressure is higher than the atmospheric pressure around the water
- C. Water boils at a lower temperature in areas of lower pressure
- D. A and C are true
Correct answer: D
Rationale: Both statements A and C are true. Water indeed boils at approximately 100°C (212°F) at standard atmospheric pressure. However, water boils at a lower temperature in areas of lower pressure due to the decreased atmospheric pressure, which affects the vapor pressure and boiling point of water. Statement B is incorrect because the boiling point is the temperature at which the vapor pressure equals the external pressure (atmospheric pressure in this case), not when it is higher.
3. How many different types of nucleotides are there in DNA?
- A. one
- B. two
- C. four
- D. eight
Correct answer: C
Rationale: The correct answer is 'C: four.' DNA is composed of four different types of nucleotides: adenine, thymine, guanine, and cytosine. These nucleotides pair up in specific combinations to form the genetic code. Choices 'A: one,' 'B: two,' and 'D: eight' are incorrect because DNA consists of a set of four distinct nucleotides, not one, two, or eight.
4. If both parents have polydactylism, what percentage of their offspring is predicted to manifest the anomaly?
- A. 25%
- B. 50%
- C. 75%
- D. 100%
Correct answer: B
Rationale: When both parents have polydactylism, they each possess at least one dominant allele for polydactylism. Through a Punnett square analysis, it can be determined that 50% of their offspring will inherit the dominant allele from both parents. This results in a 100% chance of manifesting the anomaly (2 out of 4 possibilities). Therefore, 50% of the offspring are predicted to manifest the anomaly. Choices A, C, and D are incorrect as they do not align with the principles of Mendelian genetics and Punnett square analysis.
5. RNA is made from DNA through a process called ___________.
- A. transcription
- B. synthesis
- C. translation
- D. replication
Correct answer: A
Rationale: RNA is made from DNA through a process called transcription. During transcription, an enzyme called RNA polymerase reads the DNA template and synthesizes a complementary RNA molecule. This process is essential for gene expression and allows the information encoded in DNA to be converted into functional RNA molecules. Choice B, 'synthesis,' is incorrect as it is a general term and does not specifically describe the process of RNA formation from DNA. Choice C, 'translation,' is incorrect as it refers to the process where the mRNA is used to assemble amino acids during protein synthesis, not the conversion of DNA to RNA. Choice D, 'replication,' is incorrect as it is the process of making an identical copy of DNA, not converting DNA into RNA.
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