HESI A2
HESI A2 Practice Test Biology
1. Which of the following is necessary for cell diffusion?
- A. water
- B. membrane
- C. ATP
- D. gradient
Correct answer: D
Rationale: The correct answer is 'gradient.' In cell diffusion, substances move from an area of high concentration to an area of low concentration, driven by the concentration gradient. This process does not require water, membrane, or ATP specifically. Water can aid in the movement of substances, but it is not necessary for diffusion itself. The membrane is involved in regulating diffusion but is not a requirement for the process. ATP is not directly involved in simple diffusion processes; instead, it is more related to active transport mechanisms. Therefore, the concentration gradient is essential for cell diffusion to occur.
2. Which of the following is true of the Krebs cycle?
- A. It is a redox reaction involving proteins produced during glycolysis
- B. It is a redox reaction involving sugars produced during glycolysis
- C. Protons are passed along a gradient to produce ATP
- D. It is also known as the glycolic acid cycle
Correct answer: B
Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.
3. Which type of passive transport uses proteins that change shape to move a target molecule through the membrane?
- A. Diffusion
- B. Carrier proteins
- C. Channel proteins
- D. None of the above
Correct answer: B
Rationale: The correct answer is B: Carrier proteins. Carrier proteins are involved in facilitated diffusion, a type of passive transport where specific target molecules are moved across the membrane with the help of proteins that change shape. These carrier proteins bind to the target molecule on one side of the membrane, undergo a conformational change, and then release the molecule on the other side. This process is crucial for the selective transport of certain molecules that cannot pass through the membrane by simple diffusion. Choices A and C are incorrect because diffusion and channel proteins do not involve proteins that change shape to transport target molecules selectively. Choice D is incorrect as carrier proteins fit the description provided in the question.
4. In a phospholipid molecule, the head:
- A. Is hydrophilic
- B. Is hydrophobic
- C. Is on the inner side of the layer
- D. Both A and C
Correct answer: D
Rationale: The head of a phospholipid is hydrophilic (water-loving) and is located on the outer side of the lipid bilayer, interacting with water molecules. This arrangement positions the hydrophobic tails inward, away from water. Therefore, the correct answer is D. Choice A is incorrect because the head is hydrophilic, not hydrophobic. Choice B is incorrect as the head is on the outer side, not the inner side of the layer.
5. Which is a byproduct of fermentation in muscle cells?
- A. Ethanol
- B. Pyruvic acid
- C. Lactic acid
- D. Oxygen
Correct answer: C
Rationale: Lactic acid is a byproduct of fermentation in muscle cells. During intense exercise or when oxygen is limited, muscle cells use anaerobic respiration to generate energy. This process breaks down glucose into lactic acid, which can cause muscle fatigue and soreness. Choice A, Ethanol, is not produced in muscle cells during fermentation. Choice B, Pyruvic acid, is an intermediate product in glucose metabolism but is not a byproduct of fermentation in muscle cells. Choice D, Oxygen, is not a byproduct of fermentation but a reactant in aerobic respiration.
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