HESI A2
HESI A2 Practice Test Biology
1. Which of the following is necessary for cell diffusion?
- A. water
- B. membrane
- C. ATP
- D. gradient
Correct answer: D
Rationale: The correct answer is 'gradient.' In cell diffusion, substances move from an area of high concentration to an area of low concentration, driven by the concentration gradient. This process does not require water, membrane, or ATP specifically. Water can aid in the movement of substances, but it is not necessary for diffusion itself. The membrane is involved in regulating diffusion but is not a requirement for the process. ATP is not directly involved in simple diffusion processes; instead, it is more related to active transport mechanisms. Therefore, the concentration gradient is essential for cell diffusion to occur.
2. Which component of the cell contributes to the protection, communication, and passage of substances into and out of the cell?
- A. Nucleus
- B. Cell membrane
- C. Endoplasmic reticulum
- D. Cytoplasm
Correct answer: B
Rationale: The correct answer is the cell membrane. The cell membrane is responsible for protecting the cell, facilitating communication with the external environment, and regulating the passage of substances into and out of the cell. The nucleus (Choice A) is the control center of the cell and houses the genetic material but is not primarily involved in these functions. The endoplasmic reticulum (Choice C) is involved in protein synthesis and lipid metabolism, not primarily in protection or communication. The cytoplasm (Choice D) is the gel-like substance that fills the cell but does not specifically contribute to protection, communication, or substance passage.
3. Which organelle is the site of energy production?
- A. Mitochondrion
- B. Vacuole
- C. Cell membrane
- D. Ribosome
Correct answer: A
Rationale: The correct answer is A: Mitochondrion. The mitochondrion is the site of energy production in a cell. It is often referred to as the powerhouse of the cell because it is where cellular respiration occurs, generating energy in the form of adenosine triphosphate (ATP) through processes like the citric acid cycle and oxidative phosphorylation. The other organelles listed play different roles in the cell - vacuoles store materials, the cell membrane regulates the movement of substances in and out of the cell, and ribosomes are involved in protein synthesis.
4. How are lipids different from other organic molecules?
- A. They are indivisible.
- B. They are not water soluble.
- C. They contain zinc.
- D. They form long proteins.
Correct answer: B
Rationale: The correct answer is B: 'They are not water soluble.' Lipids are not water-soluble, which distinguishes them from other organic molecules. Choice A is incorrect because lipids are not indivisible; they can be broken down into fatty acids and glycerol. Choice C is incorrect as lipids do not necessarily contain zinc; they are a diverse group of molecules. Choice D is incorrect because lipids do not form long proteins; proteins are made up of amino acids, not lipids.
5. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
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