HESI A2
Biology HESI A2 2024
1. Beeswax is an example of what kind of molecule?
- A. Lipid
- B. Carbohydrate
- C. Protein
- D. Nucleic acid
Correct answer: A
Rationale: Beeswax is primarily composed of esters of long-chain aliphatic alcohols and fatty acids, making it a type of lipid. Lipids are a diverse group of molecules that are hydrophobic in nature and have important functions in energy storage, signaling, and forming cellular membranes. Beeswax's chemical composition and properties categorize it as a lipid rather than a carbohydrate, protein, or nucleic acid. Carbohydrates are composed of sugars, proteins are made up of amino acids, and nucleic acids consist of nucleotides; none of which match the chemical composition of beeswax.
2. Which names a final step in protein synthesis?
- A. DNA unzips.
- B. Amino acids bond.
- C. Transfer RNA bonds to messenger RNA.
- D. Messenger RNA moves to ribosomes.
Correct answer: B
Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
3. Cells that line the inner or outer surfaces of organs or body cavities are often linked together by intimate physical connections. These connections are referred to as ______.
- A. Separate desmosomes
- B. Ronofilaments
- C. Tight junctions
- D. Fascia adherens
Correct answer: C
Rationale: The correct answer is C: Tight junctions. Tight junctions, also known as zonula occludens, are the intimate physical connections between cells that line the inner or outer surfaces of organs or body cavities. These junctions form a virtually impermeable barrier to fluid, creating a tight seal between the cells. This helps in maintaining the integrity and function of the tissue as well as regulating the movement of substances across the cell layer. Choice A, Separate desmosomes, are cell structures that provide strong adhesion between cells but do not create a barrier to fluid. Choice B, Ronofilaments, is not a term used to describe the connections between cells. Choice D, Fascia adherens, are another type of cell junction involved in cell adhesion, but they are different from tight junctions in terms of their structure and function.
4. A child is sick. They have a body temperature that exceeds 37ºC. The body senses this and begins to sweat in order to lower the temperature. What is this an example of?
- A. Positive feedback loop
- B. Negative feedback loop
- C. Both
- D. None of the above
Correct answer: B
Rationale: This is an example of a negative feedback loop. In a negative feedback loop, the body's response (sweating) works to counteract the initial stimulus of a high body temperature by cooling the body down. The goal is to return the body to homeostasis, maintaining a stable internal environment. Positive feedback loops amplify the initial stimulus rather than counteracting it, which is not the case here. Therefore, choices A and C are incorrect. Choice D is also incorrect as the situation described fits the characteristics of a negative feedback loop.
5. A cell is in a solution in which the concentration of solutes is higher inside the cell than outside the cell. What would you expect to happen to the cell?
- A. It will swell and possibly burst.
- B. It will shrivel and shrink.
- C. It will maintain its current size.
- D. It will grow a supportive cell wall.
Correct answer: A
Rationale: When a cell is in a solution where the concentration of solutes is higher inside the cell than outside, it is in a hypertonic environment. In this situation, water will move into the cell in an attempt to equalize the concentration of solutes on both sides of the cell membrane through the process of osmosis. As a result, the cell will swell as it takes in more water, potentially leading to bursting or cell lysis. Choice B is incorrect because a cell in a hypertonic solution will not shrivel and shrink due to water moving into the cell. Choice C is incorrect because the cell will not maintain its current size; it will swell. Choice D is incorrect because growing a supportive cell wall is not the immediate response to being in a hypertonic environment.
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