HESI A2
Biology HESI A2 Practice Test
1. A cell that does not contain membrane-bound organelles or a defined nucleus would be classified as:
- A. eukaryotic
- B. embryonic
- C. prokaryotic
- D. symbiotic
Correct answer: C
Rationale: A cell that does not contain membrane-bound organelles or a defined nucleus is classified as prokaryotic. Prokaryotic cells lack a true nucleus, and their genetic material is typically found in a region called the nucleoid. Examples of prokaryotic organisms include bacteria and archaea. Eukaryotic cells, on the other hand, contain membrane-bound organelles and a true nucleus, distinguishing them from prokaryotic cells. Embryonic and symbiotic classifications are not directly related to the presence of organelles or a nucleus in cells.
2. Most enzymes are made up of what?
- A. proteins
- B. lipids
- C. starches
- D. simple sugars
Correct answer: A
Rationale: Most enzymes are made up of proteins. Proteins are large biomolecules composed of amino acids that are vital for the structure and function of enzymes. Enzymes act as catalysts in biochemical reactions, speeding up the rate of chemical reactions in living organisms. They exhibit high specificity and efficiency due to their unique protein structures. Lipids, starches, and simple sugars are not typically the primary components of enzymes, making them incorrect choices.
3. Genes control heredity in man and other organisms. This gene is ___
- A. A segment of DNA
- B. A bead-like structure on the chromosomes
- C. A protein molecule
- D. A segment of RNA
Correct answer: A
Rationale: Genes are sections of DNA that contain instructions for building and operating living organisms. These sections of DNA contain the genetic information that is passed on from one generation to the next. Genes are composed of specific sequences of nucleotides within the DNA molecule. Therefore, genes are best described as segments of DNA. Choice A is correct. Choice B is incorrect because genes are not bead-like structures on chromosomes but specific sequences of DNA. Choice C is incorrect because genes are not protein molecules but rather sequences of nucleotides. Choice D is incorrect because genes are not segments of RNA but DNA.
4. What is the term for the breakdown of glycogen into glucose subunits?
- A. Hydrolysis
- B. Reduction
- C. Metabolism
- D. Transpiration
Correct answer: A
Rationale: Hydrolysis is the term used to describe the breakdown of large molecules into smaller units by adding water. In the case of glycogen being broken down into glucose subunits, this process involves the addition of water molecules to break the glycosidic bonds between glucose molecules, resulting in the release of individual glucose subunits. This process is crucial for providing cells with a source of energy when needed. Choice B, Reduction, refers to a chemical reaction involving a gain of electrons or a decrease in oxidation state, not the breakdown of glycogen into glucose subunits. Choice C, Metabolism, is a broad term encompassing all biochemical processes in an organism, including anabolism and catabolism, but does not specifically describe the breakdown of glycogen into glucose subunits. Choice D, Transpiration, is the process of water movement through a plant and is not related to the breakdown of glycogen into glucose subunits.
5. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
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