HESI A2
Biology HESI A2 Practice Test
1. Which of the following is true of the Krebs cycle?
- A. It is a redox reaction involving proteins produced during glycolysis
- B. It is a redox reaction involving sugars produced during glycolysis
- C. Protons are passed along a gradient to produce ATP
- D. It is also known as the glycolic acid cycle
Correct answer: B
Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.
2. Which of the following is always true about molecules?
- A. They cannot travel through all cell membranes
- B. They move from low concentration to high concentration without using energy
- C. They move from high concentration to low concentration without using energy
- D. They cannot move
Correct answer: C
Rationale: The statement that molecules move from high concentration to low concentration without using energy is always true due to the natural process of diffusion. This movement occurs to reach equilibrium and does not require any additional energy input directly from the molecule itself. Choice A is incorrect because not all molecules can travel through all cell membranes. Choice B is incorrect as molecules typically move from high concentration to low concentration in a process known as passive transport. Choice D is incorrect as molecules are in constant motion due to factors like temperature and kinetic energy.
3. A cell is in a solution in which the concentration of solutes is higher inside the cell than outside the cell. What would you expect to happen to the cell?
- A. It will swell and possibly burst.
- B. It will shrivel and shrink.
- C. It will maintain its current size.
- D. It will grow a supportive cell wall.
Correct answer: A
Rationale: When a cell is in a solution where the concentration of solutes is higher inside the cell than outside, it is in a hypertonic environment. In this situation, water will move into the cell in an attempt to equalize the concentration of solutes on both sides of the cell membrane through the process of osmosis. As a result, the cell will swell as it takes in more water, potentially leading to bursting or cell lysis. Choice B is incorrect because a cell in a hypertonic solution will not shrivel and shrink due to water moving into the cell. Choice C is incorrect because the cell will not maintain its current size; it will swell. Choice D is incorrect because growing a supportive cell wall is not the immediate response to being in a hypertonic environment.
4. If both parents have polydactylism, what percentage of their offspring is predicted to manifest the anomaly?
- A. 25%
- B. 50%
- C. 75%
- D. 100%
Correct answer: B
Rationale: When both parents have polydactylism, they each possess at least one dominant allele for polydactylism. Through a Punnett square analysis, it can be determined that 50% of their offspring will inherit the dominant allele from both parents. This results in a 100% chance of manifesting the anomaly (2 out of 4 possibilities). Therefore, 50% of the offspring are predicted to manifest the anomaly. Choices A, C, and D are incorrect as they do not align with the principles of Mendelian genetics and Punnett square analysis.
5. Which of the following is the best example of a hypothesis?
- A. Dogs like treats
- B. Red is the best color
- C. If I eat 100 donuts, then I will feel sick
- D. If a plant is exposed to red light, then it will show less growth than natural light
Correct answer: D
Rationale: Option D is the best example of a hypothesis because it presents a clear cause-and-effect relationship that can be tested through experimentation. It follows the format of 'If [cause], then [effect]' which is characteristic of a hypothesis in scientific research. The statement is specific, testable, and does not rely on personal opinions or biases, making it a strong and valid hypothesis. Choices A, B, and C do not follow the structure of a hypothesis as they lack the cause-and-effect relationship that can be tested through experimentation. They are more like statements or opinions rather than hypotheses.
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