HESI A2
Biology HESI A2 Practice Test
1. Which of the following is true of the Krebs cycle?
- A. It is a redox reaction involving proteins produced during glycolysis
- B. It is a redox reaction involving sugars produced during glycolysis
- C. Protons are passed along a gradient to produce ATP
- D. It is also known as the glycolic acid cycle
Correct answer: B
Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.
2. A cell containing 12 chromosomes divides into daughter cells in mitosis. How many chromosomes are in each daughter cell?
- A. 3
- B. 6
- C. 12
- D. 24
Correct answer: C
Rationale: During mitosis, the cell undergoes nuclear division without changing the number of chromosomes. Therefore, the daughter cells produced will have the same number of chromosomes as the parent cell. In this case, since the parent cell contains 12 chromosomes, each daughter cell will also have 12 chromosomes. Choices A, B, and D are incorrect because during mitosis, the chromosome number remains the same, and daughter cells inherit the same number of chromosomes as the parent cell.
3. A cell is in a solution in which the concentration of solutes is higher inside the cell than outside the cell. What would you expect to happen to the cell?
- A. It will swell and possibly burst.
- B. It will shrivel and shrink.
- C. It will maintain its current size.
- D. It will grow a supportive cell wall.
Correct answer: A
Rationale: When a cell is in a solution where the concentration of solutes is higher inside the cell than outside, it is in a hypertonic environment. In this situation, water will move into the cell in an attempt to equalize the concentration of solutes on both sides of the cell membrane through the process of osmosis. As a result, the cell will swell as it takes in more water, potentially leading to bursting or cell lysis. Choice B is incorrect because a cell in a hypertonic solution will not shrivel and shrink due to water moving into the cell. Choice C is incorrect because the cell will not maintain its current size; it will swell. Choice D is incorrect because growing a supportive cell wall is not the immediate response to being in a hypertonic environment.
4. Which type of sugar is a disaccharide?
- A. Sucrose
- B. Fructose
- C. Glucose
- D. Galactose
Correct answer: A
Rationale: The correct answer is A, Sucrose. Sucrose is a disaccharide composed of one molecule of glucose and one molecule of fructose. When glucose and fructose combine, they form sucrose. Choice B, Fructose, is a monosaccharide, not a disaccharide. Choice C, Glucose, is also a monosaccharide, not a disaccharide. Choice D, Galactose, is another monosaccharide and not a disaccharide.
5. How do animal cells divide?
- A. Through a contractile ring
- B. Via a cell plate
- C. Both methods
- D. None of the above
Correct answer: A
Rationale: Animal cells divide through a contractile ring made of actin and myosin filaments. The ring contracts, pinching the cell membrane in the middle to form two daughter cells. Plant cells use a cell plate due to their rigid cell walls, making choices B and C incorrect. Choice D is incorrect as animal cells do use the contractile ring method for division.
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