HESI A2
Biology HESI A2 Practice Exam
1. Which of the following are found both in open and closed circulatory systems?
- A. Arteries
- B. Red blood cells
- C. Capillaries
- D. Immune cells
Correct answer: C
Rationale: The correct answer is C, Capillaries. Capillaries are found in both open and closed circulatory systems. Capillaries are small blood vessels that connect arteries and veins, allowing for the exchange of nutrients and wastes between the blood and tissues. They are essential components of circulatory systems regardless of whether they are open or closed. Arteries (Choice A) are not found in open circulatory systems, as these systems lack distinct arteries and veins. Red blood cells (Choice B) are present in the blood but are not exclusive to either open or closed circulatory systems. Immune cells (Choice D) are not specific components of circulatory systems, as they are part of the immune system.
2. Which statement is true of enzymes?
- A. They are made from lipids.
- B. They are made from proteins.
- C. They form double chains of DNA.
- D. They bind with catalysts.
Correct answer: B
Rationale: The correct answer is B: Enzymes are made from proteins. Enzymes are biological molecules that act as catalysts to speed up chemical reactions in living organisms. While the majority of enzymes are proteins, a few are made from RNA. The statement that enzymes are made from lipids (choice A) is incorrect. Enzymes do not form double chains of DNA (choice C) as their primary function is not related to DNA structure. Additionally, enzymes themselves do not bind with catalysts (choice D); instead, they act as catalysts to facilitate reactions.
3. What happens during anaphase?
- A. Chromosomes move to opposite ends of the spindle.
- B. Nuclear membrane and nucleoli disintegrate.
- C. Chromatids line up at the center of the spindle.
- D. Nuclear membrane and nucleoli form.
Correct answer: A
Rationale: During anaphase, the sister chromatids, joined at the centromere, separate and move towards opposite ends of the spindle apparatus. This movement ensures that each daughter cell receives an identical set of chromosomes. Choice B is incorrect as the disintegration of the nuclear membrane and nucleoli occurs during prophase. Choice C is incorrect as chromatids align at the center of the spindle during metaphase, not anaphase. Choice D is incorrect as the formation of the nuclear membrane and nucleoli occurs during telophase, not anaphase.
4. In an example of a male with hemophilia and a female carrier, what ratio of the offspring are predicted neither to carry nor to manifest the disease?
- A. 0 females : 1 male
- B. 1 female : 1 male
- C. 1 female : 0 males
- D. 2 females : 1 male
Correct answer: D
Rationale: In this scenario, the male offspring will inherit the Y chromosome from the father and the X chromosome from the carrier mother. As a result, they will not have the hemophilia gene. The female offspring will inherit one X chromosome from the mother, which does not carry the hemophilia gene, and one X chromosome from the father, which does not exist due to the Y chromosome. Therefore, all female offspring will not carry or manifest hemophilia, resulting in a ratio of 2 females to 1 male. Choice A is incorrect because it does not account for the female offspring. Choices B and C are incorrect as they do not reflect the correct ratio based on the inheritance pattern of hemophilia.
5. During which phase of mitosis does the nuclear envelope disintegrate?
- A. Prophase
- B. Prophase
- C. Prometaphase
- D. Metaphase
Correct answer: C
Rationale: During the prometaphase stage of mitosis, the nuclear envelope disintegrates. This allows the condensed chromosomes to move towards the center of the cell, preparing for their alignment along the metaphase plate. The breakdown of the nuclear envelope is a crucial step in mitosis to ensure the proper segregation of genetic material into daughter cells. Choices A, B, and D are incorrect as the nuclear envelope disintegration specifically occurs during the prometaphase stage, not in prophase or metaphase.
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