HESI A2
HESI A2 Biology Practice Test 2024
1. What is the initial step in the metabolism of food to cellular energy?
- A. Citric Acid Cycle
- B. Glycolysis
- C. Electron Transport Chain
- D. Photosynthesis
Correct answer: B
Rationale: The correct answer is B: Glycolysis. Glycolysis is the initial step in the metabolism of food to cellular energy. During glycolysis, glucose is broken down into pyruvate, generating ATP and NADH. Choices A, C, and D are incorrect because the Citric Acid Cycle and Electron Transport Chain occur later in cellular respiration, while Photosynthesis is the process by which plants convert light energy into chemical energy.
2. Which molecules contain only carbon, hydrogen, and oxygen?
- A. Lipids and proteins
- B. Carbohydrates and lipids
- C. Proteins and carbohydrates
- D. Nucleic acids and proteins
Correct answer: B
Rationale: Carbohydrates and lipids are the molecules that contain only carbon, hydrogen, and oxygen. Carbohydrates such as sugars and starches are made up of carbon, hydrogen, and oxygen in a ratio of 1:2:1, while lipids such as fats and oils are composed of carbon, hydrogen, and oxygen as well. Lipids typically contain more carbon and hydrogen atoms compared to oxygen atoms. Proteins contain nitrogen in addition to carbon, hydrogen, and oxygen, while nucleic acids contain phosphorus in addition to carbon, hydrogen, and oxygen. Therefore, choices A, C, and D are incorrect as they include molecules that contain elements other than carbon, hydrogen, and oxygen.
3. Which of the following structures is not directly involved in translation?
- A. tRNA
- B. mRNA
- C. ribosome
- D. DNA
Correct answer: D
Rationale: The correct answer is 'D: DNA.' DNA is not directly involved in translation, which is the process of synthesizing proteins from mRNA. tRNA carries amino acids to the ribosome, mRNA provides the template for protein synthesis, and ribosomes are the cellular machinery where translation occurs. DNA's main role is in transcription, where it serves as the template for mRNA synthesis, not in translation.
4. Anaerobic respiration happens in _ because _ .
- A. Animals; they need energy
- B. Plants; they use sunlight
- C. Bacteria; they live in environments with low oxygen
- D. None of the above
Correct answer: C
Rationale: Anaerobic respiration happens in bacteria because they live in environments with low oxygen. Bacteria, unlike animals and plants, do not have easy access to oxygen for aerobic respiration and must find alternative ways to produce energy to survive. This makes anaerobic respiration essential for their metabolic processes. Choice A is incorrect because although animals need energy, they generally rely on aerobic respiration when oxygen is available. Choice B is incorrect because plants primarily perform photosynthesis using sunlight to produce energy. Choice D is incorrect as anaerobic respiration does occur in specific organisms like bacteria when oxygen is scarce.
5. In contrast with triglycerides, phospholipids are lacking one of which of the following components?
- A. Monosaccharide
- B. Glycerol
- C. Phosphates
- D. Fatty acid
Correct answer: B
Rationale: Phospholipids are structurally similar to triglycerides but lack one of the fatty acid chains that triglycerides possess. Triglycerides consist of three fatty acid chains attached to a glycerol molecule, while phospholipids have two fatty acid chains and a phosphate group attached to a glycerol backbone. Therefore, phospholipids are lacking the third fatty acid chain found in triglycerides. Choice A (Monosaccharide) is incorrect because neither triglycerides nor phospholipids contain monosaccharides in their structure. Choice C (Phosphates) is incorrect because phospholipids actually contain phosphates, unlike triglycerides. Choice D (Fatty acid) is incorrect as both triglycerides and phospholipids contain fatty acids, but the number of fatty acid chains differs between the two.
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