Nursing Elites

1. What is the end product of glycolysis?

• A. Lactic acid
• B. ATP
• C. NADPH
• D. Pyruvic acid

Correct answer: D

Rationale: The correct answer is D: Pyruvic acid. The end product of glycolysis is pyruvic acid, not lactic acid, ATP, or NADPH. Pyruvic acid is a key intermediary in cellular respiration and can be further metabolized to produce energy through processes like the citric acid cycle and oxidative phosphorylation. Lactic acid is produced in the absence of oxygen during fermentation, ATP is a product of cellular respiration but not the direct end product of glycolysis, and NADPH is generated in other metabolic pathways such as the pentose phosphate pathway, not in glycolysis.

2. What checkpoint mechanism ensures all chromosomes are attached to the spindle fibers before anaphase begins?

• A. Prometaphase
• B. Metaphase
• C. Cyclin degradation
• D. Sister chromatid cohesion

Correct answer: A

Rationale: A) Prometaphase is the correct answer because it is the stage of mitosis where all chromosomes are attached to the spindle fibers before anaphase begins. During prometaphase, the nuclear envelope breaks down, allowing the spindle fibers to attach to the kinetochores of the chromosomes. This attachment is necessary for proper chromosome alignment and segregation during anaphase. B) Metaphase is incorrect because it is the stage where chromosomes are aligned at the metaphase plate but do not necessarily have all spindle fibers attached. C) Cyclin degradation is incorrect because it is a regulatory mechanism that controls the progression of the cell cycle but is not specifically related to ensuring all chromosomes are attached to spindle fibers. D) Sister chromatid cohesion is incorrect because it refers to the physical connection between sister chromatids that is maintained until anaphase, but it does not ensure that all chromosomes are attached to spindle fibers.

3. What is the process of converting lactic acid back into pyruvate called?

• A. Glycolysis
• B. Gluconeogenesis
• C. Cori cycle
• D. Oxidative phosphorylation

Correct answer: C

Rationale: A) Glycolysis is the process of breaking down glucose into pyruvate. B) Gluconeogenesis is the process of synthesizing glucose from non-carbohydrate sources. C) The Cori cycle is the process by which lactic acid produced by anaerobic metabolism in muscles is transported to the liver and converted back into glucose or pyruvate. D) Oxidative phosphorylation is the process by which ATP is synthesized using energy derived from the transfer of electrons in the electron transport chain.

4. What is the importance of RNA splicing?

• A. Removes introns from the mRNA molecule
• B. Adds the poly-A tail to the mRNA molecule
• C. Activates the mRNA molecule for translation
• D. Modifies the structure of the protein

Correct answer: A

Rationale: RNA splicing is a crucial process in gene expression where non-coding regions called introns are removed from the pre-mRNA molecule, and the remaining coding regions called exons are joined together to form the mature mRNA molecule. This process ensures that only the protein-coding sequences are retained in the mRNA for translation, allowing for the production of functional proteins. Therefore, option A is the correct answer as it accurately describes the importance of RNA splicing in generating mature mRNA molecules for protein synthesis. B) Adding the poly-A tail to the mRNA molecule is a post-transcriptional modification that occurs after RNA splicing and is not directly related to the process of removing introns. C) Activating the mRNA molecule for translation is typically achieved through the addition of a 5' cap and the poly-A tail, rather than through RNA splicing. D) Modifying the structure of the protein is not directly related to the process of RNA splicing, which primarily focuses on mRNA maturation by removing non-coding introns.

5. Which type of capillary is the most permeable?

• A. Continuous capillaries
• B. Sinusoidal capillaries
• C. Fenestrated capillaries
• D. Vascular capillaries

Correct answer: B

Rationale: Sinusoidal capillaries are indeed the most permeable type. They are characterized by large gaps between endothelial cells, allowing for the passage of large molecules and cells. These capillaries are commonly found in organs like the liver, bone marrow, and spleen where high permeability is required for specialized functions such as filtration and exchange of substances. Continuous capillaries have tight junctions and are the least permeable, found in muscles, lungs, and the central nervous system where strict control over permeability is needed. Fenestrated capillaries, on the other hand, have small pores or fenestrations and are intermediate in permeability, found in organs like the kidneys, endocrine glands, and intestines where selective permeability is necessary. Vascular capillaries is not a specific type of capillary and is not a valid choice.

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