HESI A2
HESI A2 Practice Test Biology
1. Which organelle organizes protein synthesis?
- A. mitochondrion
- B. nucleus
- C. ribosome
- D. vacuole
Correct answer: C
Rationale: Ribosomes are the organelles responsible for organizing protein synthesis. They are the protein factories of the cell, where amino acids are linked together to form proteins. Mitochondria are known as the powerhouse of the cell, responsible for energy production. The nucleus contains the cell's genetic material but does not directly organize protein synthesis. Vacuoles are responsible for storage and maintaining the cell's turgidity.
2. Which names a final step in protein synthesis?
- A. DNA unzips.
- B. Amino acids bond.
- C. Transfer RNA bonds to messenger RNA.
- D. Messenger RNA moves to ribosomes.
Correct answer: B
Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
3. How many bones are included in the human skeletal system?
- A. 412
- B. 103
- C. Over 300
- D. 206
Correct answer: D
Rationale: There are 206 bones in the human skeletal system. This includes bones in the skull, spine, ribs, arms, legs, hands, and feet. The correct answer is 206 because that is the standard number of bones in an adult human body. Choices A, B, and C are incorrect as they do not reflect the accurate count of bones in the human skeletal system.
4. How many pairs of chromosomes do all humans have?
- A. 24 pairs
- B. 23 pairs
- C. 22 pairs
- D. 20 pairs
Correct answer: B
Rationale: All humans have 23 pairs of chromosomes, totaling 46 chromosomes. Choice A is incorrect because humans do not have 24 pairs. Choice C is incorrect as humans have 23 pairs, not 22 pairs. Choice D is incorrect as humans have 23 pairs of chromosomes, not 20 pairs.
5. Which organelle is responsible for detoxifying harmful substances in the cell?
- A. Endoplasmic Reticulum
- B. Lysosomes
- C. Peroxisomes
- D. Golgi Apparatus
Correct answer: C
Rationale: The correct answer is C, Peroxisomes. Peroxisomes are responsible for detoxifying harmful substances in the cell by breaking down fatty acids and producing hydrogen peroxide. This process helps protect the cell from damage caused by toxic substances. Choice A, Endoplasmic Reticulum, is involved in protein and lipid synthesis, not detoxification. Choice B, Lysosomes, contain enzymes for digestion and waste removal, not primarily detoxification. Choice D, Golgi Apparatus, is responsible for modifying, sorting, and packaging proteins for secretion, not detoxification.
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