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HESI A2

HESI A2 Biology Practice Test

1. Epithelial cells are:

Correct answer: A

Rationale: Epithelial cells have a distinct top (apical) and bottom (basal) side, demonstrating polarity. This polarity is essential for their specialized functions, such as secretion, absorption, and barrier formation. Choice B, 'Neutral,' is incorrect as epithelial cells exhibit polarity. Choice C, 'Larger than other cells,' is incorrect as epithelial cells come in various sizes and are not specifically larger than other cell types. Choice D, 'None of the above,' is incorrect as epithelial cells are indeed polarized.

2. In an example of a male with hemophilia and a female carrier, what percentage of the offspring is predicted to be carriers only?

Correct answer: C

Rationale: In this scenario, the male offspring will inherit the X chromosome with the hemophilia gene from the mother, as males have one X chromosome inherited from their mother. The female offspring will inherit one normal X chromosome from the father and one X chromosome with the hemophilia gene from the mother, making them carriers of the hemophilia trait. Therefore, 50% of the offspring will be carriers only. Option A (0%) is incorrect as female offspring will inherit the X chromosome with the hemophilia gene from the mother. Option B (25%) is incorrect as the female offspring will not be unaffected. Option D (100%) is incorrect as not all offspring will be carriers, only the female offspring.

3. What event occurs during telophase?

Correct answer: D

Rationale: During telophase, the final stage of mitosis, the separated chromosomes reach opposite poles of the cell. At this stage, a new nuclear envelope forms around each set of chromosomes, creating two distinct nuclei. This marks the completion of cell division. Choices A, B, and C are incorrect because the disappearance of the nuclear envelope typically occurs during prophase, organelles do not double in number during telophase, and chromosomes separate during anaphase, not telophase.

4. Ocean waves may tear sponges into pieces, each of which may grow into a new sponge. What is this form of reproduction called?

Correct answer: D

Rationale: Fragmentation is the form of asexual reproduction where an organism breaks into fragments, and each fragment can grow into a new individual. In the case of sponges being torn into pieces by ocean waves, each piece has the potential to develop into a new sponge, making fragmentation the correct answer in this scenario. Budding is a form of asexual reproduction where a new organism develops as an outgrowth from the parent organism. Vegetative propagation involves the growth of new individuals from plant parts like stems or roots. Binary fission is a method of reproduction seen in some single-celled organisms where one cell divides into two identical cells.

5. How many chromosomes do sperm and egg produce in meiosis?

Correct answer: B

Rationale: Sperm and egg cells undergo meiosis to form gametes with half the number of chromosomes found in somatic cells. Each sperm and egg cell produces 23 chromosomes through meiosis. Choice A is incorrect because 46 chromosomes represent the diploid number found in somatic cells. Choice C is incorrect as it is an uncommon number for chromosome production in human gametes. Choice D is incorrect as the total number of chromosomes in sperm or egg cells is 23, not 24.

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