HESI A2
HESI A2 Practice Test Biology
1. What is the first step in the conversion of glucose to pyruvate?
- A. Glycolysis
- B. Krebs cycle
- C. Electron transport chain
- D. Aerobic respiration
Correct answer: A
Rationale: The correct answer is Glycolysis. Glycolysis is the initial step in the conversion of glucose to pyruvate. During glycolysis, glucose is broken down into pyruvate through a series of enzymatic reactions. Choice B, the Krebs cycle, occurs after glycolysis in aerobic cellular respiration. Choice C, the Electron transport chain, is the final step in aerobic respiration where the majority of ATP is produced. Choice D, Aerobic respiration, is a broader term that encompasses glycolysis, the Krebs cycle, and the electron transport chain, but it is not the specific first step in the conversion of glucose to pyruvate.
2. How many pairs of homologous chromosomes do humans have?
- A. 13
- B. 23
- C. 26
- D. 46
Correct answer: D
Rationale: The correct answer is D: 46. Humans have 23 pairs of chromosomes, which include 22 pairs of autosomes and 1 pair of sex chromosomes. Homologous chromosomes are pairs of chromosomes that contain the same genes, one from each parent. Therefore, humans have a total of 46 chromosomes, with 23 pairs of homologous chromosomes. Choices A, B, and C are incorrect as they do not represent the total number of chromosomes in humans or the number of pairs of homologous chromosomes.
3. What is the role of tRNA during protein synthesis?
- A. Carries amino acids to the ribosome
- B. Links nucleotides together
- C. Copies DNA sequences
- D. Replicates genetic material
Correct answer: A
Rationale: During protein synthesis, tRNA plays the crucial role of carrying amino acids to the ribosome. This process ensures that the correct amino acids are brought to the ribosome according to the mRNA sequence. Choice B, linking nucleotides together, refers to the role of RNA polymerase in transcription, not tRNA. Choice C, copying DNA sequences, is the function of DNA polymerase during DNA replication, while choice D, replicating genetic material, is an overarching function of DNA replication, not specific to tRNA's role in protein synthesis.
4. Which structure controls the passage of substances into and out of the cell?
- A. Vacuole
- B. Cell Membrane
- C. Nuclear Membrane
- D. Cytoplasm
Correct answer: B
Rationale: The correct answer is the Cell Membrane. The cell membrane acts as a barrier that controls the passage of substances into and out of the cell. It is selectively permeable, allowing only certain molecules to pass through. Vacuole (Choice A), Nuclear Membrane (Choice C), and Cytoplasm (Choice D) do not primarily regulate the passage of substances in and out of the cell. Vacuoles are responsible for storage, the nuclear membrane surrounds the nucleus providing protection, and the cytoplasm is the fluid where organelles are suspended.
5. Choose the two bases that have two carbon rings:
- A. Adenine
- B. Cytosine
- C. Thymine
- D. Guanine
Correct answer: A
Rationale: Adenine and guanine have two carbon rings and are known as purines. These bases are found in nucleic acids such as DNA and RNA. Adenine (option A) and guanine (option D) are the correct choices as they both have two carbon rings in their molecular structure. Cytosine (option B) and thymine (option C) have a single carbon ring each, making them incorrect choices for bases with two carbon rings.
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