HESI A2
HESI A2 Practice Test Biology
1. What is the first step in the conversion of glucose to pyruvate?
- A. Glycolysis
- B. Krebs cycle
- C. Electron transport chain
- D. Aerobic respiration
Correct answer: A
Rationale: The correct answer is Glycolysis. Glycolysis is the initial step in the conversion of glucose to pyruvate. During glycolysis, glucose is broken down into pyruvate through a series of enzymatic reactions. Choice B, the Krebs cycle, occurs after glycolysis in aerobic cellular respiration. Choice C, the Electron transport chain, is the final step in aerobic respiration where the majority of ATP is produced. Choice D, Aerobic respiration, is a broader term that encompasses glycolysis, the Krebs cycle, and the electron transport chain, but it is not the specific first step in the conversion of glucose to pyruvate.
2. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
3. Which type of sugar is a disaccharide?
- A. Sucrose
- B. Fructose
- C. Glucose
- D. Galactose
Correct answer: A
Rationale: The correct answer is A, Sucrose. Sucrose is a disaccharide composed of one molecule of glucose and one molecule of fructose. When glucose and fructose combine, they form sucrose. Choice B, Fructose, is a monosaccharide, not a disaccharide. Choice C, Glucose, is also a monosaccharide, not a disaccharide. Choice D, Galactose, is another monosaccharide and not a disaccharide.
4. Athletes are often concerned with the question of what they need in their diets to increase muscle mass and strength. What biologic molecule would you recommend that would accomplish this?
- A. carbohydrates
- B. proteins
- C. lipids
- D. nucleic acids
Correct answer: B
Rationale: Proteins are essential for building and repairing muscle tissue. They contain amino acids, which are the building blocks of muscles. Athletes looking to increase muscle mass and strength should focus on consuming adequate amounts of high-quality proteins in their diets. Carbohydrates provide energy for workouts, lipids are important for overall health but do not directly contribute to muscle building, and nucleic acids are involved in genetic activities rather than muscle growth.
5. Which of the following molecules is an important component of the plasma membrane?
- A. Phospholipids
- B. Steroids
- C. Sugars
- D. Amino acids
Correct answer: A
Rationale: Phospholipids are indeed a crucial component of the plasma membrane. They have a unique structure with hydrophilic heads and hydrophobic tails, which allows them to form the lipid bilayer of the membrane. Steroids, sugars, and amino acids are not primary components of the plasma membrane. Steroids are a different type of lipid, sugars are often found in glycoproteins on the membrane surface, and amino acids are the building blocks of proteins, some of which are membrane proteins, but not the membrane itself.
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