HESI A2
HESI A2 Practice Test Biology
1. What is the first step in the conversion of glucose to pyruvate?
- A. Glycolysis
- B. Krebs cycle
- C. Electron transport chain
- D. Aerobic respiration
Correct answer: A
Rationale: The correct answer is Glycolysis. Glycolysis is the initial step in the conversion of glucose to pyruvate. During glycolysis, glucose is broken down into pyruvate through a series of enzymatic reactions. Choice B, the Krebs cycle, occurs after glycolysis in aerobic cellular respiration. Choice C, the Electron transport chain, is the final step in aerobic respiration where the majority of ATP is produced. Choice D, Aerobic respiration, is a broader term that encompasses glycolysis, the Krebs cycle, and the electron transport chain, but it is not the specific first step in the conversion of glucose to pyruvate.
2. During which phase of cell division do the chromosomes replicate?
- A. Prophase
- B. Interphase
- C. Anaphase
- D. Telophase
Correct answer: B
Rationale: Chromosomes replicate during the interphase of the cell cycle. Interphase is the phase where the cell prepares for division by undergoing various activities such as growth, DNA replication, and protein synthesis. During DNA replication in interphase, each chromosome in the cell is duplicated to form two sister chromatids, which are then separated during cell division. Prophase is the phase where the chromosomes condense, and the nuclear envelope breaks down. Anaphase is the phase where sister chromatids are pulled apart towards opposite poles of the cell. Telophase is the phase where the nuclear envelope reforms, and chromosomes begin to decondense.
3. Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. In an example of an unaffected father and a female carrier who have two daughters and two sons, which is the predicted outcome?
- A. Both daughters will carry the disease.
- B. Both sons will carry the disease.
- C. One daughter may have the disease.
- D. One son may have the disease.
Correct answer: C
Rationale: Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. Since the father is unaffected and does not carry the disease, he must have a normal X chromosome. The mother is a carrier, which means she has one normal X chromosome and one X chromosome with the disease allele. The daughters will inherit one X chromosome from each parent; one would be normal, and the other has a chance of carrying the disease allele. So, there is a 50% chance that one daughter may have the disease, as she could inherit the X chromosome with the disease allele. The sons will inherit the Y chromosome from the father and the X chromosome from the mother, so they will not be affected by the disease. Therefore, the predicted outcome is that one daughter may have the disease, while the sons will not carry the disease. This rules out choices A, B, and D.
4. Where is the site of cellular respiration in eukaryotic cells?
- A. Nucleus
- B. Chloroplasts
- C. Mitochondria
- D. Ribosomes
Correct answer: C
Rationale: The correct answer is C: Mitochondria. Mitochondria are often referred to as the powerhouse of the cell because they are responsible for cellular respiration in eukaryotic cells. During cellular respiration, mitochondria generate energy in the form of ATP. Choices A, B, and D are incorrect. The nucleus is the organelle that houses the cell's genetic material, chloroplasts are responsible for photosynthesis in plant cells, and ribosomes are involved in protein synthesis, not cellular respiration.
5. How does water affect the temperature of a living thing?
- A. Water increases temperature.
- B. Water keeps temperature stable.
- C. Water decreases temperature.
- D. Water does not affect temperature.
Correct answer: B
Rationale: Water has a high specific heat capacity, which means it can absorb and release large amounts of heat with minimal temperature change. This property helps water regulate the temperature of living things by maintaining a stable environment. Choice A is incorrect because water does not consistently increase temperature, but rather helps in temperature regulation. Choice C is incorrect as water doesn't typically decrease temperature in living organisms. Choice D is incorrect since water does play a crucial role in regulating temperature.
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