HESI A2
HESI A2 Practice Test Biology
1. What is the first step in the conversion of glucose to pyruvate?
- A. Glycolysis
- B. Krebs cycle
- C. Electron transport chain
- D. Aerobic respiration
Correct answer: A
Rationale: The correct answer is Glycolysis. Glycolysis is the initial step in the conversion of glucose to pyruvate. During glycolysis, glucose is broken down into pyruvate through a series of enzymatic reactions. Choice B, the Krebs cycle, occurs after glycolysis in aerobic cellular respiration. Choice C, the Electron transport chain, is the final step in aerobic respiration where the majority of ATP is produced. Choice D, Aerobic respiration, is a broader term that encompasses glycolysis, the Krebs cycle, and the electron transport chain, but it is not the specific first step in the conversion of glucose to pyruvate.
2. Which of the following is true of the Krebs cycle?
- A. It is a redox reaction involving proteins produced during glycolysis
- B. It is a redox reaction involving sugars produced during glycolysis
- C. Protons are passed along a gradient to produce ATP
- D. It is also known as the glycolic acid cycle
Correct answer: B
Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.
3. Why do gardeners sometimes use salt to get rid of slugs?
- A. The salt moves from the exterior into the slug’s body.
- B. The salt causes water in the slug to move outward.
- C. The salt and slug slime merge to form a new compound.
- D. The salt’s corrosiveness breaks down the slug’s cell walls.
Correct answer: D
Rationale: Gardeners use salt to get rid of slugs because salt is corrosive and breaks down the slug's cell walls. When the slug comes into contact with salt, the salt draws moisture out of the slug's body, causing dehydration and ultimately leading to the slug's death. Choices A, B, and C are incorrect because the primary mechanism of salt in eliminating slugs is its corrosive action on the slug's body, not the movement of salt into the slug's body, outward movement of water in the slug, or merging with slug slime to form a new compound.
4. During protein synthesis, what process creates a complementary strand of RNA from a DNA template?
- A. Transcription
- B. Translation
- C. Transformation
- D. Replication
Correct answer: A
Rationale: The correct answer is 'Transcription.' During protein synthesis, transcription is the process that creates a complementary RNA strand from a DNA template. This process involves the synthesis of mRNA using DNA as a template. Choice B, 'Translation,' is incorrect as it is the process where the genetic code carried by mRNA is decoded to produce a specific polypeptide chain. Choice C, 'Transformation,' is not related to the synthesis of RNA from a DNA template. Choice D, 'Replication,' is the process of copying DNA to produce an identical DNA molecule, not RNA.
5. What organelle pushes water out of the cell?
- A. Lysosomes
- B. Vacuoles (contractile)
- C. Mitochondria
- D. Nucleus
Correct answer: B
Rationale: The correct answer is B: Vacuoles (contractile). Vacuoles (contractile) are responsible for expelling excess water out of the cell. Lysosomes are involved in the digestion and removal of waste materials, mitochondria are the powerhouse of the cell involved in energy production, and the nucleus contains the cell's genetic material but does not play a role in pushing water out of the cell.
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