HESI A2
HESI A2 Practice Test Biology
1. What is the first step in the conversion of glucose to pyruvate?
- A. Glycolysis
- B. Krebs cycle
- C. Electron transport chain
- D. Aerobic respiration
Correct answer: A
Rationale: The correct answer is Glycolysis. Glycolysis is the initial step in the conversion of glucose to pyruvate. During glycolysis, glucose is broken down into pyruvate through a series of enzymatic reactions. Choice B, the Krebs cycle, occurs after glycolysis in aerobic cellular respiration. Choice C, the Electron transport chain, is the final step in aerobic respiration where the majority of ATP is produced. Choice D, Aerobic respiration, is a broader term that encompasses glycolysis, the Krebs cycle, and the electron transport chain, but it is not the specific first step in the conversion of glucose to pyruvate.
2. What is the initial step in the metabolism of food to cellular energy?
- A. Citric Acid Cycle
- B. Glycolysis
- C. Electron Transport Chain
- D. Photosynthesis
Correct answer: B
Rationale: The correct answer is B: Glycolysis. Glycolysis is the initial step in the metabolism of food to cellular energy. During glycolysis, glucose is broken down into pyruvate, generating ATP and NADH. Choices A, C, and D are incorrect because the Citric Acid Cycle and Electron Transport Chain occur later in cellular respiration, while Photosynthesis is the process by which plants convert light energy into chemical energy.
3. During which phase of cell division do the chromosomes replicate?
- A. Prophase
- B. Interphase
- C. Anaphase
- D. Telophase
Correct answer: B
Rationale: Chromosomes replicate during the interphase of the cell cycle. Interphase is the phase where the cell prepares for division by undergoing various activities such as growth, DNA replication, and protein synthesis. During DNA replication in interphase, each chromosome in the cell is duplicated to form two sister chromatids, which are then separated during cell division. Prophase is the phase where the chromosomes condense, and the nuclear envelope breaks down. Anaphase is the phase where sister chromatids are pulled apart towards opposite poles of the cell. Telophase is the phase where the nuclear envelope reforms, and chromosomes begin to decondense.
4. What are the three types of muscle tissue?
- A. Cardiac, spinal, stomach
- B. Smooth, skeletal, cardiac
- C. Neuron, epithelial, collagen
- D. None of the above
Correct answer: B
Rationale: The correct answer is B: Smooth, skeletal, cardiac. Smooth muscle is found in organs like the stomach and is involuntarily controlled. Skeletal muscle is found in voluntary muscles, like the bicep or quadriceps. Cardiac muscle is found only in the heart walls and works involuntarily to make the heart beat and pump blood. Choices A, C, and D are incorrect because they do not represent the three types of muscle tissue.
5. Which structure might be described as a core of nucleic acid surrounded by a protein coat?
- A. RNA
- B. Virus
- C. Blue-green alga
- D. Saprophyte
Correct answer: B
Rationale: A virus can be described as a core of nucleic acid (either RNA or DNA) surrounded by a protein coat, known as a capsid. This structure distinguishes viruses from other microorganisms such as blue-green algae (Cyanobacteria), fungi known as saprophytes, or individual RNA molecules. Viruses depend on a host cell to replicate and are considered non-living entities due to their inability to carry out metabolic functions independently.
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