HESI A2
HESI A2 Practice Test Biology
1. What is the first step in the conversion of glucose to pyruvate?
- A. Glycolysis
- B. Krebs cycle
- C. Electron transport chain
- D. Aerobic respiration
Correct answer: A
Rationale: The correct answer is Glycolysis. Glycolysis is the initial step in the conversion of glucose to pyruvate. During glycolysis, glucose is broken down into pyruvate through a series of enzymatic reactions. Choice B, the Krebs cycle, occurs after glycolysis in aerobic cellular respiration. Choice C, the Electron transport chain, is the final step in aerobic respiration where the majority of ATP is produced. Choice D, Aerobic respiration, is a broader term that encompasses glycolysis, the Krebs cycle, and the electron transport chain, but it is not the specific first step in the conversion of glucose to pyruvate.
2. Which one of the following best describes the function of a cell membrane?
- A. It controls the substances entering and leaving the cell.
- B. It maintains the cell's shape.
- C. It controls the substances entering the cell.
- D. It supports the cell's structures.
Correct answer: A
Rationale: The correct answer is A. The function of a cell membrane is to control the substances entering and leaving the cell. The cell membrane is selectively permeable, allowing it to regulate the movement of ions and molecules in and out of the cell to maintain internal balance and proper function. Choice B is incorrect because while the cell membrane does provide some structural support, its primary function is not to maintain the cell's shape. Choice C is incorrect because the cell membrane controls both the substances entering and leaving the cell, not just those entering. Choice D is incorrect as the primary function of the cell membrane is not to support the cell's structures but to regulate the movement of substances.
3. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
4. Which gives the order of four taxonomic categories from least to most specific?
- A. Kingdom, phylum, class, order
- B. Kingdom, phylum, order, class
- C. Kingdom, order, phylum, class
- D. Kingdom, class, order, phylum
Correct answer: A
Rationale: The correct order of the four taxonomic categories from least to most specific is Kingdom, phylum, class, and order. This sequence adheres to the hierarchical system of classification where organisms are grouped based on shared characteristics, becoming more specific as you move from Kingdom to order. Choice B is incorrect as the order of 'order' and 'class' is swapped. Choice C is incorrect as 'order' precedes 'phylum' instead of following it. Choice D is incorrect as 'class' should come before 'order'.
5. Which of the following molecules is an important component of the plasma membrane?
- A. Phospholipids
- B. Steroids
- C. Sugars
- D. Amino acids
Correct answer: A
Rationale: Phospholipids are indeed a crucial component of the plasma membrane. They have a unique structure with hydrophilic heads and hydrophobic tails, which allows them to form the lipid bilayer of the membrane. Steroids, sugars, and amino acids are not primary components of the plasma membrane. Steroids are a different type of lipid, sugars are often found in glycoproteins on the membrane surface, and amino acids are the building blocks of proteins, some of which are membrane proteins, but not the membrane itself.
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