HESI A2
HESI A2 Practice Test Biology
1. What is the first step in the conversion of glucose to pyruvate?
- A. Glycolysis
- B. Krebs cycle
- C. Electron transport chain
- D. Aerobic respiration
Correct answer: A
Rationale: The correct answer is Glycolysis. Glycolysis is the initial step in the conversion of glucose to pyruvate. During glycolysis, glucose is broken down into pyruvate through a series of enzymatic reactions. Choice B, the Krebs cycle, occurs after glycolysis in aerobic cellular respiration. Choice C, the Electron transport chain, is the final step in aerobic respiration where the majority of ATP is produced. Choice D, Aerobic respiration, is a broader term that encompasses glycolysis, the Krebs cycle, and the electron transport chain, but it is not the specific first step in the conversion of glucose to pyruvate.
2. In an example of a male with hemophilia and a female carrier, what ratio of the offspring are predicted neither to carry nor to manifest the disease?
- A. 0 females : 1 male
- B. 1 female : 1 male
- C. 1 female : 0 males
- D. 2 females : 1 male
Correct answer: D
Rationale: In this scenario, the male offspring will inherit the Y chromosome from the father and the X chromosome from the carrier mother. As a result, they will not have the hemophilia gene. The female offspring will inherit one X chromosome from the mother, which does not carry the hemophilia gene, and one X chromosome from the father, which does not exist due to the Y chromosome. Therefore, all female offspring will not carry or manifest hemophilia, resulting in a ratio of 2 females to 1 male. Choice A is incorrect because it does not account for the female offspring. Choices B and C are incorrect as they do not reflect the correct ratio based on the inheritance pattern of hemophilia.
3. Why do gardeners sometimes use salt to get rid of slugs?
- A. The salt moves from the exterior into the slug’s body.
- B. The salt causes water in the slug to move outward.
- C. The salt and slug slime merge to form a new compound.
- D. The salt’s corrosiveness breaks down the slug’s cell walls.
Correct answer: D
Rationale: Gardeners use salt to get rid of slugs because salt is corrosive and breaks down the slug's cell walls. When the slug comes into contact with salt, the salt draws moisture out of the slug's body, causing dehydration and ultimately leading to the slug's death. Choices A, B, and C are incorrect because the primary mechanism of salt in eliminating slugs is its corrosive action on the slug's body, not the movement of salt into the slug's body, outward movement of water in the slug, or merging with slug slime to form a new compound.
4. In a phospholipid molecule, the head:
- A. Is hydrophilic
- B. Is hydrophobic
- C. Is on the inner side of the layer
- D. Both A and C
Correct answer: D
Rationale: The head of a phospholipid is hydrophilic (water-loving) and is located on the outer side of the lipid bilayer, interacting with water molecules. This arrangement positions the hydrophobic tails inward, away from water. Therefore, the correct answer is D. Choice A is incorrect because the head is hydrophilic, not hydrophobic. Choice B is incorrect as the head is on the outer side, not the inner side of the layer.
5. Which of these is not an example of a lipid?
- A. Butter
- B. Wax
- C. Canola oil
- D. Honey
Correct answer: D
Rationale: Honey is not an example of a lipid because lipids are fat-related molecules that are insoluble in water, while honey is a natural sweet substance made by bees and primarily consists of sugars such as glucose and fructose. Butter, wax, and canola oil are examples of lipids as they are all composed of fat-related molecules that do not dissolve in water.
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