HESI A2
HESI A2 Practice Test Biology
1. What is the first step in the conversion of glucose to pyruvate?
- A. Glycolysis
- B. Krebs cycle
- C. Electron transport chain
- D. Aerobic respiration
Correct answer: A
Rationale: The correct answer is Glycolysis. Glycolysis is the initial step in the conversion of glucose to pyruvate. During glycolysis, glucose is broken down into pyruvate through a series of enzymatic reactions. Choice B, the Krebs cycle, occurs after glycolysis in aerobic cellular respiration. Choice C, the Electron transport chain, is the final step in aerobic respiration where the majority of ATP is produced. Choice D, Aerobic respiration, is a broader term that encompasses glycolysis, the Krebs cycle, and the electron transport chain, but it is not the specific first step in the conversion of glucose to pyruvate.
2. Which of the following organelles is responsible for producing ATP in cells?
- A. Nucleus
- B. Mitochondrion
- C. Chloroplast
- D. Lysosome
Correct answer: B
Rationale: The correct answer is 'Mitochondrion.' Mitochondria are known as the powerhouse of the cell and are responsible for producing ATP, the energy currency of the cell. The nucleus is responsible for storing genetic material and controlling cell activities, not for ATP production. Chloroplasts are found in plant cells and are responsible for photosynthesis, not ATP production. Lysosomes are involved in digestion and waste removal, not ATP production.
3. Which of the following is true of the Krebs cycle?
- A. It is a redox reaction involving proteins produced during glycolysis
- B. It is a redox reaction involving sugars produced during glycolysis
- C. Protons are passed along a gradient to produce ATP
- D. It is also known as the glycolic acid cycle
Correct answer: B
Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.
4. Which cellular structure is largely protective in function?
- A. Mitochondrion
- B. Vacuole
- C. Cell membrane
- D. Ribosome
Correct answer: C
Rationale: The correct answer is C: Cell membrane. The cell membrane, also known as the plasma membrane, is largely protective in function as it serves as a selectively permeable barrier that surrounds the cell, providing structural support and helping to maintain cell integrity. It regulates the movement of substances in and out of the cell, thus protecting the cell from harmful external factors while allowing essential nutrients to enter. Mitochondrion (choice A) is responsible for energy production, not primarily protective. Vacuole (choice B) is mainly involved in storage and transport. Ribosome (choice D) is involved in protein synthesis, not protective functions.
5. Ocean waves may tear sponges into pieces, each of which may grow into a new sponge. What is this form of reproduction called?
- A. Budding
- B. Vegetative propagation
- C. Binary fission
- D. Fragmentation
Correct answer: D
Rationale: Fragmentation is the form of asexual reproduction where an organism breaks into fragments, and each fragment can grow into a new individual. In the case of sponges being torn into pieces by ocean waves, each piece has the potential to develop into a new sponge, making fragmentation the correct answer in this scenario. Budding is a form of asexual reproduction where a new organism develops as an outgrowth from the parent organism. Vegetative propagation involves the growth of new individuals from plant parts like stems or roots. Binary fission is a method of reproduction seen in some single-celled organisms where one cell divides into two identical cells.
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