what is the first step in the conversion of glucose to pyruvate
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HESI A2

HESI A2 Practice Test Biology

1. What is the first step in the conversion of glucose to pyruvate?

Correct answer: A

Rationale: The correct answer is Glycolysis. Glycolysis is the initial step in the conversion of glucose to pyruvate. During glycolysis, glucose is broken down into pyruvate through a series of enzymatic reactions. Choice B, the Krebs cycle, occurs after glycolysis in aerobic cellular respiration. Choice C, the Electron transport chain, is the final step in aerobic respiration where the majority of ATP is produced. Choice D, Aerobic respiration, is a broader term that encompasses glycolysis, the Krebs cycle, and the electron transport chain, but it is not the specific first step in the conversion of glucose to pyruvate.

2. Athletes are often concerned with the question of what they need in their diets to increase muscle mass and strength. What biologic molecule would you recommend that would accomplish this?

Correct answer: B

Rationale: Proteins are essential for building and repairing muscle tissue. They contain amino acids, which are the building blocks of muscles. Athletes looking to increase muscle mass and strength should focus on consuming adequate amounts of high-quality proteins in their diets. Carbohydrates provide energy for workouts, lipids are important for overall health but do not directly contribute to muscle building, and nucleic acids are involved in genetic activities rather than muscle growth.

3. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?

Correct answer: B

Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.

4. Three students measured the mass of a product of combustion. They recorded measurements of 14 g, 16 g, and 17 g. If the known mass of the product is 30 g, how would you describe the students’ measurements?

Correct answer: B

Rationale: The students' measurements are precise because they are consistently close to each other. However, they are not accurate because all the measurements deviate from the known mass of the product (30 g). Accuracy refers to how close a measurement is to the true or accepted value, while precision refers to the level of agreement among repeated measurements. Since the students' measurements are consistent but do not align with the true value, they can be considered precise but not accurate. Choice A is incorrect because accuracy relates to the proximity of the measurements to the true value, which is not the case here. Choice C is incorrect because although the measurements are precise, they are not accurate. Choice D is incorrect because the measurements are precise as they show good agreement with each other, even though they are not accurate.

5. How does an enzyme work on a chemical reaction that occurs in a substrate?

Correct answer: B

Rationale: Enzymes are biological catalysts that facilitate chemical reactions by lowering the activation energy required for the reaction to occur. This allows the reaction to proceed more quickly and efficiently. Enzymes do not change the overall outcome of the reaction, but they significantly increase the rate at which it takes place. Therefore, choice B, 'An enzyme speeds up the chemical reaction,' is the correct answer. Choices A, C, and D are incorrect because enzymes do not slow down, have no effect, or stop chemical reactions; instead, they accelerate the process by lowering the activation energy.

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