HESI A2
Biology HESI A2 Practice Test
1. The apical side of an epithelial cell:
- A. Is exposed to fluid or air
- B. Is on the bottom side of the cell
- C. Does not allow any substances to pass through
- D. None of the above
Correct answer: A
Rationale: The apical side of an epithelial cell is the top side, which is typically exposed to fluids, air, or the inside of an organ. This side allows substances to pass through it, facilitating the absorption, secretion, or excretion of various substances. Choice B is incorrect as the apical side is not on the bottom but the top side. Choice C is incorrect as the apical side does allow substances to pass through. Choice D is incorrect as there are characteristics associated with the apical side.
2. Which of the following is the best example of a hypothesis?
- A. Dogs like treats
- B. Red is the best color
- C. If I eat 100 donuts, then I will feel sick
- D. If a plant is exposed to red light, then it will show less growth than natural light
Correct answer: D
Rationale: Option D is the best example of a hypothesis because it presents a clear cause-and-effect relationship that can be tested through experimentation. It follows the format of 'If [cause], then [effect]' which is characteristic of a hypothesis in scientific research. The statement is specific, testable, and does not rely on personal opinions or biases, making it a strong and valid hypothesis. Choices A, B, and C do not follow the structure of a hypothesis as they lack the cause-and-effect relationship that can be tested through experimentation. They are more like statements or opinions rather than hypotheses.
3. Which organelle organizes protein synthesis?
- A. mitochondrion
- B. nucleus
- C. ribosome
- D. vacuole
Correct answer: C
Rationale: Ribosomes are the organelles responsible for organizing protein synthesis. They are the protein factories of the cell, where amino acids are linked together to form proteins. Mitochondria are known as the powerhouse of the cell, responsible for energy production. The nucleus contains the cell's genetic material but does not directly organize protein synthesis. Vacuoles are responsible for storage and maintaining the cell's turgidity.
4. In an example of a male with hemophilia and a female carrier, what ratio of the offspring are predicted neither to carry nor to manifest the disease?
- A. 0 females : 1 male
- B. 1 female : 1 male
- C. 1 female : 0 males
- D. 2 females : 1 male
Correct answer: D
Rationale: In this scenario, the male offspring will inherit the Y chromosome from the father and the X chromosome from the carrier mother. As a result, they will not have the hemophilia gene. The female offspring will inherit one X chromosome from the mother, which does not carry the hemophilia gene, and one X chromosome from the father, which does not exist due to the Y chromosome. Therefore, all female offspring will not carry or manifest hemophilia, resulting in a ratio of 2 females to 1 male. Choice A is incorrect because it does not account for the female offspring. Choices B and C are incorrect as they do not reflect the correct ratio based on the inheritance pattern of hemophilia.
5. Which of the following is true of homozygous traits?
- A. They are haploid
- B. They are denoted AA
- C. They are denoted aa
- D. They are denoted Aa
Correct answer: B
Rationale: Homozygous traits have two identical forms of the gene, either both dominant (AA) or both recessive (aa). Therefore, choices B and C are true for homozygous traits. Choice A is incorrect because being haploid refers to having a single set of chromosomes, not necessarily homozygous traits. Choice D is incorrect as homozygous traits have identical alleles, so they are not denoted as Aa.
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