what happens when a protein unfolds

ATI TEAS 7

ATI TEAS 7 science review

1. What happens when a protein unfolds?

A. Activation
B. Denaturation
C. Renaturation
D. Folding

Correct answer: B

Rationale: - Activation (Option A) refers to the process of initiating or increasing the activity of a molecule, such as an enzyme. Protein unfolding does not involve activation. - Denaturation (Option B) is the correct answer. Denaturation refers to the process by which a protein loses its three-dimensional structure, leading to the disruption of its function. This can be caused by factors such as heat, pH changes, or chemicals. - Renaturation (Option C) is the process by which a denatured protein regains its native structure and function. Protein unfolding is the opposite of renaturation. - Folding (Option D) is the process by which a protein assumes its functional three-dimensional structure. Unfolding is the reverse process of folding, not folding itself.

2. Which organelle is responsible for the final stages of protein modification and packaging for secretion in animal cells?

A. Rough endoplasmic reticulum (RER)
B. Smooth endoplasmic reticulum (SER)
C. Ribosomes
D. Golgi apparatus

Correct answer: D

Rationale: The Golgi apparatus is responsible for the final stages of protein modification and packaging for secretion in animal cells. After proteins are synthesized in the rough endoplasmic reticulum (RER), they are transported to the Golgi apparatus for further processing, sorting, and packaging before being sent to their final destination within or outside the cell. The smooth endoplasmic reticulum (SER) is mainly involved in lipid metabolism and detoxification processes, not protein modification. Ribosomes are the cellular organelles responsible for protein synthesis, not the final stages of protein modification and packaging for secretion, which is the role of the Golgi apparatus.

3. In order to verify if a particular drug is responsible for the recovery of individuals with a disorder, what procedure would be most effective in testing its effectiveness?

A. Ensure that neither the subjects nor the investigators know which subjects are given the drug and which are given the placebo.
B. Ensure that the subjects do not know whether they are given the drug or the placebo, but the investigators are aware of who has received the medication.
C. Ensure that the investigators do not know whether they are administering the drug or the placebo, but the subjects do know which they are receiving.
D. Ensure that both the investigators and the subjects have full knowledge of which subjects are getting the drug and which are getting a placebo.

Correct answer: A

Rationale: The most effective procedure in testing whether the drug is responsible for the recovery is to ensure that neither the subjects nor the investigators know which subjects are given the drug and which are given the placebo. This method is known as a double-blind study, which helps eliminate biases and ensures that the results are reliable and not influenced by expectations or beliefs. By keeping both the subjects and investigators unaware of who is receiving the drug or placebo, the study can accurately determine the true impact of the drug on recovery. Choice B is incorrect as it only prevents the subjects from knowing which treatment they are receiving, allowing for potential bias from the investigators. Choice C is also incorrect as it allows for potential bias from the subjects. Choice D is incorrect as full knowledge of treatment allocation can introduce bias and affect the study's validity.

4. Which of the following is NOT a factor affecting the rate of a chemical reaction?

A. Concentration of reactants
B. Temperature
C. Presence of a catalyst
D. Color of the reaction mixture

Correct answer: D

Rationale: The color of the reaction mixture is not a factor affecting the rate of a chemical reaction. Factors such as the concentration of reactants, temperature, and the presence of a catalyst can influence the rate of a chemical reaction by affecting the frequency of collisions between reactant molecules and the energy of those collisions. The color of the reaction mixture is a physical property and does not directly impact the kinetics or speed of the reaction process. It is a qualitative observation that does not alter the reaction rate or mechanisms involved.

5. What makes bone resistant to shattering?

A. The calcium salts deposited in the bone
B. The collagen fibers
C. The bone marrow and network of blood vessels
D. The intricate balance of minerals and collagen fibers

Correct answer: D

Rationale: Bone is resistant to shattering due to the intricate balance of minerals and collagen fibers. The minerals provide strength to the bone, while the collagen fibers offer flexibility. This combination ensures that bone is a robust and resilient tissue. Choice A (The calcium salts deposited in the bone) is incorrect as calcium salts alone do not provide the necessary flexibility for bone to withstand shattering. Choice B (The collagen fibers) is partially correct as collagen fibers contribute to the flexibility of bone but alone are not sufficient for resistance to shattering. Choice C (The bone marrow and network of blood vessels) is incorrect as they do not directly contribute to the physical resistance of bone to shattering.