Nursing Elites

1. What checkpoint mechanism ensures all chromosomes are attached to the spindle fibers before anaphase begins?

• A. Prometaphase
• B. Metaphase
• C. Cyclin degradation
• D. Sister chromatid cohesion

Correct answer: A

Rationale: A) Prometaphase is the correct answer because it is the stage of mitosis where all chromosomes are attached to the spindle fibers before anaphase begins. During prometaphase, the nuclear envelope breaks down, allowing the spindle fibers to attach to the kinetochores of the chromosomes. This attachment is necessary for proper chromosome alignment and segregation during anaphase. B) Metaphase is incorrect because it is the stage where chromosomes are aligned at the metaphase plate but do not necessarily have all spindle fibers attached. C) Cyclin degradation is incorrect because it is a regulatory mechanism that controls the progression of the cell cycle but is not specifically related to ensuring all chromosomes are attached to spindle fibers. D) Sister chromatid cohesion is incorrect because it refers to the physical connection between sister chromatids that is maintained until anaphase, but it does not ensure that all chromosomes are attached to spindle fibers.

2. What is the difference between emphysema and chronic bronchitis, both chronic obstructive pulmonary diseases (COPD)?

• A. Emphysema damages alveoli, while chronic bronchitis inflames airways.
• B. Emphysema causes coughing, while chronic bronchitis leads to shortness of breath.
• C. Emphysema is more reversible than chronic bronchitis.
• D. Emphysema affects only smokers, while chronic bronchitis can occur in non-smokers.

Correct answer: A

Rationale: Emphysema is characterized by the destruction of alveoli in the lungs, leading to decreased surface area for gas exchange. Chronic bronchitis, on the other hand, involves inflammation and narrowing of the airways, leading to excessive mucus production and coughing. Therefore, the correct difference between emphysema and chronic bronchitis is that emphysema damages the alveoli, while chronic bronchitis inflames the airways. Choice B is incorrect because chronic bronchitis is associated with coughing, not emphysema. Choice C is incorrect as chronic bronchitis is typically less reversible compared to emphysema. Choice D is incorrect as both emphysema and chronic bronchitis are commonly seen in smokers, but chronic bronchitis can also occur in non-smokers due to other factors such as air pollution or genetic predisposition.

3. Differentiate between gene therapy and genetic engineering in the context of human intervention.

• A. Gene therapy aims to modify existing genes within body cells, while genetic engineering manipulates genes in embryos to be passed on to offspring.
• B. Gene therapy focuses on treating genetic diseases, while genetic engineering enhances desirable traits or eliminates undesirable ones.
• C. Both involve directly altering the DNA sequence, but gene therapy targets somatic cells and genetic engineering modifies germline cells.
• D. There is no fundamental difference; both terms are synonymous.

Correct answer: B

Rationale: A) Incorrect. Gene therapy does aim to modify existing genes within body cells, but genetic engineering does not necessarily manipulate genes in embryos to be passed on to offspring. Genetic engineering can involve modifying genes in any type of cell, not just embryos. B) Correct. Gene therapy is a medical intervention that aims to treat genetic diseases by correcting or replacing faulty genes within an individual's body cells. On the other hand, genetic engineering involves modifying genes to enhance specific traits or eliminate undesirable ones, often in the context of agriculture or biotechnology. C) Incorrect. While both gene therapy and genetic engineering involve altering DNA sequences, the distinction lies in the target cells. Gene therapy targets somatic cells (non-reproductive cells), while genetic engineering typically involves modifying germline cells (reproductive cells that can pass on genetic changes to offspring). D) Incorrect. There is

4. In which direction do the particles of the medium move in a transverse wave?

• A. Perpendicular to the direction of wave travel
• B. Parallel to the direction of wave travel
• C. In a circular motion
• D. Opposite to the direction of wave travel

Correct answer: A

Rationale: In a transverse wave, the particles of the medium move perpendicular to the direction of wave travel. This means that the particles move up and down or side to side as the wave passes through the medium. This motion creates crests and troughs in the wave, leading to the characteristic oscillation observed in transverse waves. Choice B is incorrect because in transverse waves, the particle movement is not parallel to the direction of wave travel. Choice C is incorrect as the particles do not move in a circular motion in a transverse wave. Choice D is incorrect as the particles do not move opposite to the direction of wave travel; they move perpendicular to it.

5. What is the technical term for the free edges of your fingernails and toenails?

• A. Lunula (The lunula is the white crescent moon shape at the base of the nail)
• B. Matrix (The matrix is the area under the nail where new nail cells are produced)
• C. Hyponychium (This is the skin under the free edge of the nail)
• D. Free edge

Correct answer: C

Rationale: The correct answer is C, hyponychium. The hyponychium is the skin under the free edge of the nail, responsible for sealing the nail to the fingertip and protecting the nail bed from bacteria and debris. The lunula (choice A) refers to the white crescent moon shape at the base of the nail. The matrix (choice B) is the area under the nail where new nail cells are produced. The free edge (choice D) is the part of the nail that extends beyond the fingertip or toe.

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