HESI A2
Biology HESI A2 Practice Test
1. The fur color in a population of dogs is controlled by two alleles: black (B) and tan (b). The black allele exhibits complete dominance. If the phenotype of the dog is tan fur, what is its genotype?
- A. BB
- B. Bb
- C. bb
- D. Not enough information
Correct answer: C
Rationale: The correct answer is C: "bb." Since tan fur is the recessive trait controlled by the allele 'b,' the only possible genotype for a dog with tan fur is 'bb.' If a dog had the genotype 'BB' or 'Bb,' the dominant trait (black fur) would be expressed, not tan fur. Choice D, 'Not enough information,' is incorrect because based on the information provided, we can deduce the genotype of a dog with tan fur.
2. In a strand of DNA, you would expect to see adenine paired with ___________.
- A. cytosine
- B. uracil
- C. thymine
- D. guanine
Correct answer: C
Rationale: In a strand of DNA, adenine always pairs with thymine through two hydrogen bonds. This pairing is a fundamental aspect of DNA structure, where adenine and thymine complement each other in the double helix. Choice A (cytosine) is incorrect because adenine does not pair with cytosine in DNA. Choice B (uracil) is incorrect as uracil is found in RNA, not DNA. Choice D (guanine) is incorrect as guanine pairs with cytosine, not adenine, in DNA.
3. Which of the following is not true about enzymes?
- A. They catalyze reactions
- B. They lower the activation energy needed
- C. They have an active site
- D. They are typically proteins
Correct answer: B
Rationale: Enzymes lower the activation energy needed for a reaction to occur, not raise it. By lowering the activation energy, enzymes facilitate reactions, making them occur more easily and rapidly. Choice A is correct as enzymes indeed catalyze reactions. Choice C is correct as enzymes have specific active sites where substrates bind. Choice D is correct as enzymes are commonly proteins, although some RNA molecules also exhibit catalytic properties.
4. Select the option that best shows complementary base pairing in DNA:
- A. A and G
- B. A and C
- C. A and A
- D. A and T
Correct answer: D
Rationale: The correct answer is D. A purine (A) must pair with a pyrimidine (T) in DNA. This eliminates options A and C as they do not follow the rule of complementary base pairing. Adenine (A) always pairs with thymine (T) due to their specific shape and bonding properties in DNA structure. Choice B is incorrect because adenine does not pair with cytosine in DNA.
5. Which of the following structures is not directly involved in translation?
- A. tRNA
- B. mRNA
- C. ribosome
- D. DNA
Correct answer: D
Rationale: The correct answer is 'D: DNA.' DNA is not directly involved in translation, which is the process of synthesizing proteins from mRNA. tRNA carries amino acids to the ribosome, mRNA provides the template for protein synthesis, and ribosomes are the cellular machinery where translation occurs. DNA's main role is in transcription, where it serves as the template for mRNA synthesis, not in translation.
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