HESI A2
Biology HESI A2 Practice Test
1. The fur color in a population of dogs is controlled by two alleles: black (B) and tan (b). The black allele exhibits complete dominance. If the phenotype of the dog is tan fur, what is its genotype?
- A. BB
- B. Bb
- C. bb
- D. Not enough information
Correct answer: C
Rationale: The correct answer is C: "bb." Since tan fur is the recessive trait controlled by the allele 'b,' the only possible genotype for a dog with tan fur is 'bb.' If a dog had the genotype 'BB' or 'Bb,' the dominant trait (black fur) would be expressed, not tan fur. Choice D, 'Not enough information,' is incorrect because based on the information provided, we can deduce the genotype of a dog with tan fur.
2. In a phospholipid molecule, the head:
- A. Is hydrophilic
- B. Is hydrophobic
- C. Is on the inner side of the layer
- D. Both A and C
Correct answer: D
Rationale: The head of a phospholipid is hydrophilic (water-loving) and is located on the outer side of the lipid bilayer, interacting with water molecules. This arrangement positions the hydrophobic tails inward, away from water. Therefore, the correct answer is D. Choice A is incorrect because the head is hydrophilic, not hydrophobic. Choice B is incorrect as the head is on the outer side, not the inner side of the layer.
3. Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. In an example of an unaffected father and a female carrier who have two daughters and two sons, which is the predicted outcome?
- A. Both daughters will carry the disease.
- B. Both sons will carry the disease.
- C. One daughter may have the disease.
- D. One son may have the disease.
Correct answer: C
Rationale: Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. Since the father is unaffected and does not carry the disease, he must have a normal X chromosome. The mother is a carrier, which means she has one normal X chromosome and one X chromosome with the disease allele. The daughters will inherit one X chromosome from each parent; one would be normal, and the other has a chance of carrying the disease allele. So, there is a 50% chance that one daughter may have the disease, as she could inherit the X chromosome with the disease allele. The sons will inherit the Y chromosome from the father and the X chromosome from the mother, so they will not be affected by the disease. Therefore, the predicted outcome is that one daughter may have the disease, while the sons will not carry the disease. This rules out choices A, B, and D.
4. Which form of fermentation is used to produce beer?
- A. Lactic acid fermentation
- B. Acetic acid fermentation
- C. Propionic acid fermentation
- D. Ethyl alcohol fermentation
Correct answer: D
Rationale: The correct answer is D, Ethyl alcohol fermentation. During beer production, yeast metabolizes sugars in the wort to produce ethanol (ethyl alcohol) and carbon dioxide, which are responsible for the alcohol content and carbonation in beer. Choices A, B, and C are incorrect because lactic acid fermentation produces lactic acid, acetic acid fermentation produces acetic acid, and propionic acid fermentation produces propionic acid, none of which are used in the production of beer.
5. In an example of a male with hemophilia and a female carrier, what ratio of the offspring are predicted neither to carry nor to manifest the disease?
- A. 0 females : 1 male
- B. 1 female : 1 male
- C. 1 female : 0 males
- D. 2 females : 1 male
Correct answer: D
Rationale: In this scenario, the male offspring will inherit the Y chromosome from the father and the X chromosome from the carrier mother. As a result, they will not have the hemophilia gene. The female offspring will inherit one X chromosome from the mother, which does not carry the hemophilia gene, and one X chromosome from the father, which does not exist due to the Y chromosome. Therefore, all female offspring will not carry or manifest hemophilia, resulting in a ratio of 2 females to 1 male. Choice A is incorrect because it does not account for the female offspring. Choices B and C are incorrect as they do not reflect the correct ratio based on the inheritance pattern of hemophilia.
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