which phase of mitosis involves the chromosomes aligning in the center of the cell
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HESI A2

HESI A2 Biology Practice Test 2024

1. During which phase of mitosis do the chromosomes align in the center of the cell?

Correct answer: B

Rationale: The correct answer is Metaphase. During Metaphase, the chromosomes line up along the center of the cell's equator, forming the metaphase plate. This alignment ensures that during the subsequent phase, Anaphase, the sister chromatids can separate and move towards opposite poles. Prophase is the initial phase of mitosis where chromosomes condense and the nuclear envelope breaks down. Telophase is the final phase of mitosis where two new nuclei form.

2. 72 chromosomes undergo meiosis. How many chromosomes will be in each gamete?

Correct answer: A

Rationale: During meiosis, the number of chromosomes is halved in each gamete. Since 72 chromosomes undergo meiosis, each gamete will contain half of that number, which is 36 chromosomes. Therefore, the correct answer is 18 chromosomes in each gamete. Choice B (36 chromosomes) is incorrect because it represents the total number of chromosomes that undergo meiosis, not the number in each gamete. Choice C (72 chromosomes) is incorrect as it represents the initial number of chromosomes, not the number in each gamete after meiosis. Choice D (144 chromosomes) is incorrect as it doubles the initial number of chromosomes, which is not the outcome of meiosis.

3. Which of the following is true of heterozygous traits?

Correct answer: D

Rationale: Heterozygous traits are denoted by having two different alleles for a particular gene, represented as Aa. This means that they are not haploid (A), not denoted AA (B), and not denoted aa (C). Therefore, the correct answer is D, as heterozygous traits are represented as Aa.

4. Which of the following is true of the Krebs cycle?

Correct answer: B

Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.

5. How should a researcher test the hypothesis that practicing yoga reduces blood pressure?

Correct answer: B

Rationale: Option B is the most appropriate way to test the hypothesis that practicing yoga reduces blood pressure. By dividing 30 female participants into two groups with similar average blood pressure levels and testing each participant's blood pressure after participating in a yoga class, the researcher can effectively evaluate the impact of yoga on blood pressure. This design allows for a comparison between the two groups, helping to isolate the effects of yoga practice on blood pressure. Option A only involves one male and one female participant, which may not provide a representative sample. Option C introduces an additional variable of watching television, which could confound the results. Option D lacks consistency in the experimental design by switching the activities between men and women, making it difficult to attribute any observed changes solely to yoga practice.

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