which phase of mitosis involves the chromosomes aligning in the center of the cell
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HESI A2

HESI A2 Biology Practice Test 2024

1. During which phase of mitosis do the chromosomes align in the center of the cell?

Correct answer: B

Rationale: The correct answer is Metaphase. During Metaphase, the chromosomes line up along the center of the cell's equator, forming the metaphase plate. This alignment ensures that during the subsequent phase, Anaphase, the sister chromatids can separate and move towards opposite poles. Prophase is the initial phase of mitosis where chromosomes condense and the nuclear envelope breaks down. Telophase is the final phase of mitosis where two new nuclei form.

2. Which of these is not an example of a lipid?

Correct answer: D

Rationale: Honey is not an example of a lipid because lipids are fat-related molecules that are insoluble in water, while honey is a natural sweet substance made by bees and primarily consists of sugars such as glucose and fructose. Butter, wax, and canola oil are examples of lipids as they are all composed of fat-related molecules that do not dissolve in water.

3. During which phase of mitosis does the nuclear envelope disintegrate?

Correct answer: C

Rationale: During the prometaphase stage of mitosis, the nuclear envelope disintegrates. This allows the condensed chromosomes to move towards the center of the cell, preparing for their alignment along the metaphase plate. The breakdown of the nuclear envelope is a crucial step in mitosis to ensure the proper segregation of genetic material into daughter cells. Choices A, B, and D are incorrect as the nuclear envelope disintegration specifically occurs during the prometaphase stage, not in prophase or metaphase.

4. Choose the two bases that have two carbon rings:

Correct answer: A

Rationale: Adenine and guanine have two carbon rings and are known as purines. These bases are found in nucleic acids such as DNA and RNA. Adenine (option A) and guanine (option D) are the correct choices as they both have two carbon rings in their molecular structure. Cytosine (option B) and thymine (option C) have a single carbon ring each, making them incorrect choices for bases with two carbon rings.

5. How many different types of nucleotides are there in DNA?

Correct answer: C

Rationale: The correct answer is 'C: four.' DNA is composed of four different types of nucleotides: adenine, thymine, guanine, and cytosine. These nucleotides pair up in specific combinations to form the genetic code. Choices 'A: one,' 'B: two,' and 'D: eight' are incorrect because DNA consists of a set of four distinct nucleotides, not one, two, or eight.

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