which phase of mitosis involves the chromosomes aligning in the center of the cell
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HESI A2

HESI A2 Biology Practice Test 2024

1. During which phase of mitosis do the chromosomes align in the center of the cell?

Correct answer: B

Rationale: The correct answer is Metaphase. During Metaphase, the chromosomes line up along the center of the cell's equator, forming the metaphase plate. This alignment ensures that during the subsequent phase, Anaphase, the sister chromatids can separate and move towards opposite poles. Prophase is the initial phase of mitosis where chromosomes condense and the nuclear envelope breaks down. Telophase is the final phase of mitosis where two new nuclei form.

2. The procedure to focus an image using a compound microscope involves

Correct answer: B

Rationale: When using a compound microscope, it is essential to adjust the fine adjustment knob each time you switch to a new magnification level. The fine adjustment knob allows for precise focusing on the specimen at different magnifications, ensuring a clear and sharp image. The coarse adjustment knob is typically used only at the lower magnification settings to bring the image into view roughly. Adjusting the stage may be necessary based on the size and thickness of the specimen, but it does not need to be done every time a new magnification is selected. Therefore, option B is the correct choice as it focuses on the key aspect of precise focusing during magnification changes.

3. Which statement is untrue?

Correct answer: D

Rationale: DNA can be altered through various processes such as mutations, genetic engineering, and epigenetic modifications. Changes in DNA can occur naturally or through external influences, leading to variations in the genetic code. Therefore, the statement that DNA cannot be altered is untrue. Choices A, B, and C are true statements. RNA is indeed single-stranded, RNA contains uracil instead of thymine, and DNA serves as a template for protein synthesis.

4. Which statement is true of enzymes?

Correct answer: B

Rationale: The correct answer is B: Enzymes are made from proteins. Enzymes are biological molecules that act as catalysts to speed up chemical reactions in living organisms. While the majority of enzymes are proteins, a few are made from RNA. The statement that enzymes are made from lipids (choice A) is incorrect. Enzymes do not form double chains of DNA (choice C) as their primary function is not related to DNA structure. Additionally, enzymes themselves do not bind with catalysts (choice D); instead, they act as catalysts to facilitate reactions.

5. Which organelle contains the genetic material of the cell?

Correct answer: D

Rationale: The correct answer is 'D: Nucleus.' The nucleus is the organelle that contains the cell's genetic material, which is the DNA. The genetic material in the nucleus controls the cell's activities and plays a crucial role in inheritance. Choices A, B, and C are incorrect because the Golgi apparatus is involved in modifying, sorting, and packaging of proteins; ribosomes are involved in protein synthesis; and endoplasmic reticulum is involved in protein and lipid synthesis and transportation, but none of them contain the genetic material of the cell.

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