HESI A2
HESI A2 Biology Practice Test 2024
1. Which organelle is involved in the synthesis of proteins?
- A. Endoplasmic Reticulum
- B. Ribosomes
- C. Lysosomes
- D. Vacuoles
Correct answer: B
Rationale: Ribosomes are the organelles involved in the synthesis of proteins. They are the cellular machinery responsible for translating mRNA into proteins, making them essential for cell function and structure. The other organelles listed, such as the Endoplasmic Reticulum, Lysosomes, and Vacuoles, have different functions unrelated to protein synthesis. The Endoplasmic Reticulum plays a role in protein processing and transport, Lysosomes are involved in digestion and waste removal, and Vacuoles are responsible for storage and maintaining cell turgor pressure.
2. During which phase of mitosis do the chromosomes align in the center of the cell?
- A. Prophase
- B. Metaphase
- C. Telophase
- D. Anaphase
Correct answer: B
Rationale: The correct answer is Metaphase. During Metaphase, the chromosomes line up along the center of the cell's equator, forming the metaphase plate. This alignment ensures that during the subsequent phase, Anaphase, the sister chromatids can separate and move towards opposite poles. Prophase is the initial phase of mitosis where chromosomes condense and the nuclear envelope breaks down. Telophase is the final phase of mitosis where two new nuclei form.
3. Which molecules contain only carbon, hydrogen, and oxygen?
- A. Lipids and proteins
- B. Carbohydrates and lipids
- C. Proteins and carbohydrates
- D. Nucleic acids and proteins
Correct answer: B
Rationale: Carbohydrates and lipids are the molecules that contain only carbon, hydrogen, and oxygen. Carbohydrates such as sugars and starches are made up of carbon, hydrogen, and oxygen in a ratio of 1:2:1, while lipids such as fats and oils are composed of carbon, hydrogen, and oxygen as well. Lipids typically contain more carbon and hydrogen atoms compared to oxygen atoms. Proteins contain nitrogen in addition to carbon, hydrogen, and oxygen, while nucleic acids contain phosphorus in addition to carbon, hydrogen, and oxygen. Therefore, choices A, C, and D are incorrect as they include molecules that contain elements other than carbon, hydrogen, and oxygen.
4. Which of the following is always true about molecules?
- A. They cannot travel through all cell membranes
- B. They move from low concentration to high concentration without using energy
- C. They move from high concentration to low concentration without using energy
- D. They cannot move
Correct answer: C
Rationale: The statement that molecules move from high concentration to low concentration without using energy is always true due to the natural process of diffusion. This movement occurs to reach equilibrium and does not require any additional energy input directly from the molecule itself. Choice A is incorrect because not all molecules can travel through all cell membranes. Choice B is incorrect as molecules typically move from high concentration to low concentration in a process known as passive transport. Choice D is incorrect as molecules are in constant motion due to factors like temperature and kinetic energy.
5. Epithelial cells are:
- A. Polarized
- B. Neutral
- C. Larger than other cells
- D. None of the above
Correct answer: A
Rationale: Epithelial cells have a distinct top (apical) and bottom (basal) side, demonstrating polarity. This polarity is essential for their specialized functions, such as secretion, absorption, and barrier formation. Choice B, 'Neutral,' is incorrect as epithelial cells exhibit polarity. Choice C, 'Larger than other cells,' is incorrect as epithelial cells come in various sizes and are not specifically larger than other cell types. Choice D, 'None of the above,' is incorrect as epithelial cells are indeed polarized.
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