HESI A2
HESI A2 Biology Practice Test 2024
1. Which organelle is involved in the synthesis of proteins?
- A. Endoplasmic Reticulum
- B. Ribosomes
- C. Lysosomes
- D. Vacuoles
Correct answer: B
Rationale: Ribosomes are the organelles involved in the synthesis of proteins. They are the cellular machinery responsible for translating mRNA into proteins, making them essential for cell function and structure. The other organelles listed, such as the Endoplasmic Reticulum, Lysosomes, and Vacuoles, have different functions unrelated to protein synthesis. The Endoplasmic Reticulum plays a role in protein processing and transport, Lysosomes are involved in digestion and waste removal, and Vacuoles are responsible for storage and maintaining cell turgor pressure.
2. Which of the following bases is not present in RNA?
- A. Adenine
- B. Thymine
- C. Uracil
- D. Cytosine
Correct answer: B
Rationale: Thymine is not present in RNA. RNA uses uracil as one of its bases, which pairs with adenine. In RNA, adenine does not pair with thymine as in DNA. Cytosine and guanine are the other two bases found in both RNA and DNA.
3. What is the fundamental unit of life?
- A. Atom
- B. Cell
- C. Tissue
- D. Organ
Correct answer: B
Rationale: The correct answer is 'B: Cell.' Cells are indeed the fundamental unit of life as they are responsible for all living functions, including growth, reproduction, and maintaining homeostasis. While atoms are the basic building blocks of matter, cells are the smallest structural and functional unit of living organisms. Choices C and D, tissue and organ respectively, are composed of multiple cells working together and are not considered the basic unit of life.
4. How many pairs of homologous chromosomes do humans have?
- A. 13
- B. 23
- C. 26
- D. 46
Correct answer: D
Rationale: The correct answer is D: 46. Humans have 23 pairs of chromosomes, which include 22 pairs of autosomes and 1 pair of sex chromosomes. Homologous chromosomes are pairs of chromosomes that contain the same genes, one from each parent. Therefore, humans have a total of 46 chromosomes, with 23 pairs of homologous chromosomes. Choices A, B, and C are incorrect as they do not represent the total number of chromosomes in humans or the number of pairs of homologous chromosomes.
5. Which part of cellular respiration produces the greatest amount of ATP?
- A. electron transport chain
- B. glycolysis
- C. citric acid cycle
- D. fermentation
Correct answer: A
Rationale: The electron transport chain (ETC) produces the greatest amount of ATP during cellular respiration. This process occurs in the inner mitochondrial membrane and involves the transfer of electrons through a series of protein complexes, creating a proton gradient that drives the synthesis of ATP. By utilizing the energy from the electron carriers NADH and FADH2 produced in earlier stages of cellular respiration, the ETC can generate a large amount of ATP efficiently through oxidative phosphorylation. Glycolysis only produces a small amount of ATP in comparison to the ETC. The citric acid cycle generates some ATP but not as much as the ETC. Fermentation does not produce ATP through oxidative phosphorylation and yields a much smaller amount of ATP compared to the ETC.
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