HESI A2
HESI A2 Biology Practice Test
1. Where is DNA stored?
- A. The nucleus
- B. Ribosomes
- C. Endoplasmic reticulum
- D. Mitochondria
Correct answer: A
Rationale: DNA is stored in the nucleus of a cell. The nucleus houses the cell's genetic material, including the DNA, which contains the instructions for building and operating the cell. The nucleus controls the activities of the cell and is essential for proper cell function and reproduction. Ribosomes are responsible for protein synthesis, not DNA storage. The endoplasmic reticulum is involved in protein and lipid synthesis, storage, and transport but does not store DNA. Mitochondria are known as the powerhouse of the cell, producing energy in the form of ATP, but they do not store DNA.
2. In which phase of mitosis do new nuclear membranes form around sets of chromosomes?
- A. Prophase
- B. Anaphase
- C. Telophase
- D. Interphase
Correct answer: C
Rationale: The correct answer is C, Telophase. During telophase, the final phase of mitosis, new nuclear membranes form around sets of chromosomes at the opposite poles of the cell. This process marks the completion of nuclear division in mitosis. Choices A, B, and D are incorrect because in prophase, chromosomes condense but nuclear membranes are not formed; in anaphase, chromosomes separate and move to opposite poles but no new nuclear membranes are formed; and in interphase, the cell prepares for division but nuclear membranes are not forming around sets of chromosomes.
3. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
4. Enzymes can _ reactions.
- A. Catalyze
- B. Inhibit
- C. Stop
- D. None of the above
Correct answer: A
Rationale: Enzymes function as catalysts that promote and accelerate chemical reactions in biological systems. They do this by lowering the activation energy required for the reactions to occur, thereby speeding up the process without being consumed in the reaction. Enzymes facilitate reactions rather than inhibiting or stopping them. Therefore, the correct answer is 'Catalyze.' 'Inhibit' and 'Stop' are incorrect because enzymes do not hinder or halt reactions but rather enhance them.
5. Which of the following is the structure of the male reproductive system that stores spermatozoa during the maturation process?
- A. vas deferens
- B. scrotum
- C. epididymis
- D. testicular artery
Correct answer: C
Rationale: The epididymis is the structure of the male reproductive system that stores spermatozoa during the maturation process. Sperm cells produced in the testes move to the epididymis, where they mature and become motile before being ejaculated. The vas deferens is responsible for transporting mature sperm to the urethra during ejaculation, the scrotum holds the testes and helps regulate their temperature for sperm production, and the testicular artery supplies blood to the testes. Therefore, choices A, B, and D are incorrect as they do not play a direct role in storing spermatozoa during the maturation process.
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