HESI A2
Biology HESI A2 2024
1. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
2. What takes place in a lysosome?
- A. Ribosomes are made.
- B. Food is produced.
- C. Water is stored.
- D. Food is digested.
Correct answer: D
Rationale: In a lysosome, food particles are digested through the action of enzymes. Lysosomes are membrane-bound organelles containing digestive enzymes that break down large molecules into smaller ones, allowing the cell to utilize the nutrients for energy and other processes. Choices A, B, and C are incorrect because ribosomes are not made in lysosomes, food is not produced in lysosomes, and lysosomes do not store water.
3. Which organelle is found in protists but not in monerans?
- A. Golgi apparatus
- B. Chromosome
- C. Cytoplasm
- D. Cell membrane
Correct answer: A
Rationale: The Golgi apparatus is the correct answer. The Golgi apparatus is a cellular organelle responsible for processing and packaging proteins before they are transported to their final destination. Protists, being eukaryotic organisms, have membrane-bound organelles including the Golgi apparatus, which are absent in monerans. Monerans are prokaryotic organisms that lack membrane-bound structures such as the Golgi apparatus. Choices B, C, and D are incorrect as chromosomes, cytoplasm, and cell membranes are present in both protists and monerans.
4. During which phase of cell division do the chromosomes replicate?
- A. Prophase
- B. Interphase
- C. Anaphase
- D. Telophase
Correct answer: B
Rationale: Chromosomes replicate during the interphase of the cell cycle. Interphase is the phase where the cell prepares for division by undergoing various activities such as growth, DNA replication, and protein synthesis. During DNA replication in interphase, each chromosome in the cell is duplicated to form two sister chromatids, which are then separated during cell division. Prophase is the phase where the chromosomes condense, and the nuclear envelope breaks down. Anaphase is the phase where sister chromatids are pulled apart towards opposite poles of the cell. Telophase is the phase where the nuclear envelope reforms, and chromosomes begin to decondense.
5. How does asexual reproduction differ from sexual reproduction?
- A. asexual reproduction results in all cells being identical to the original cell; sexual reproduction results in half of the cells being identical to the original cell
- B. asexual reproduction results in two cells that contribute genetic material to daughter cells, resulting in significantly greater variation
- C. sexual reproduction involves two cells that contribute genetic material to daughter cells, resulting in significantly greater variation
- D. sexual reproduction involves one cell that yields all cells produced to be identical
Correct answer: C
Rationale: Sexual reproduction involves two cells (gametes) that contribute genetic material to daughter cells, resulting in significantly greater genetic variation in the offspring. This genetic variation is essential for evolution and adaptation to environmental changes. In contrast, asexual reproduction involves one cell dividing to produce offspring that are genetically identical to the parent cell. Choice A is incorrect because sexual reproduction does not result in half of the cells being identical to the original cell; it involves two cells contributing genetic material. Choice B is incorrect because asexual reproduction does not result in significantly greater variation; it produces genetically identical offspring. Choice D is incorrect because sexual reproduction involves two cells contributing genetic material, not one cell yielding all identical cells.
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