HESI A2
Biology HESI A2 2024
1. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
2. Where is DNA stored?
- A. The nucleus
- B. Ribosomes
- C. Endoplasmic reticulum
- D. Mitochondria
Correct answer: A
Rationale: DNA is stored in the nucleus of a cell. The nucleus houses the cell's genetic material, including the DNA, which contains the instructions for building and operating the cell. The nucleus controls the activities of the cell and is essential for proper cell function and reproduction. Ribosomes are responsible for protein synthesis, not DNA storage. The endoplasmic reticulum is involved in protein and lipid synthesis, storage, and transport but does not store DNA. Mitochondria are known as the powerhouse of the cell, producing energy in the form of ATP, but they do not store DNA.
3. What are the two catabolic pathways that lead to cellular energy production?
- A. Fermentation and internal respiration
- B. Fermentation and external respiration
- C. Fermentation and cellular respiration
- D. Fermentation and anaerobic respiration
Correct answer: C
Rationale: The correct answer is 'Fermentation and cellular respiration.' Fermentation is an anaerobic catabolic process that occurs in the absence of oxygen, producing limited amounts of ATP. Cellular respiration, on the other hand, is the aerobic catabolic pathway that occurs in the presence of oxygen and is the most efficient way of producing ATP. Choices A, B, and D are incorrect because internal respiration, external respiration, and anaerobic respiration are not the correct pathways leading to cellular energy production.
4. Why is polarity the most important characteristic of water?
- A. the results of the polarity are hydrogen bonding, a high specific heat value, and its versatile solvent properties
- B. the results of the polarity are covalent bonding, a low specific heat value, and its versatile solvent properties
- C. the results of the polarity are ionic bonding, a high specific heat value, and its versatile solvent properties
- D. the results of the polarity are hydrogen bonding, a low specific heat value, and its versatile solvent properties
Correct answer: A
Rationale: Polarity is the most important characteristic of water because it results in hydrogen bonding, a high specific heat value, and its versatile solvent properties. These unique properties enable water to form hydrogen bonds with other substances, resist temperature changes, and dissolve a wide variety of solutes, making it essential for life processes. Choice B is incorrect because water exhibits hydrogen bonding, not covalent bonding. Choice C is incorrect as water does not form ionic bonds. Choice D is incorrect because water has a high, not low, specific heat value, which is vital for its role in temperature regulation.
5. Why is homeostasis necessary?
- A. It maintains temperature
- B. It maintains pH
- C. It maintains glucose levels
- D. All of the above
Correct answer: D
Rationale: Homeostasis is necessary because it ensures the maintenance of a stable, relatively constant internal environment. This includes regulating various factors such as temperature, pH levels, and glucose levels to support optimal bodily functions and overall health. Choices A, B, and C are all correct as they represent key aspects of homeostasis that contribute to maintaining the body's internal balance.
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