imagine that two parents both carry the recessive gene for cystic fibrosis any homozygous recessive offspring will manifest the disease what percentag
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HESI A2

Biology HESI A2 2024

1. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?

Correct answer: B

Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.

2. During which phase is the chromosome number reduced from diploid to haploid?

Correct answer: D

Rationale: The correct answer is 'meiosis I.' During meiosis I, the chromosome number is reduced from diploid to haploid through two rounds of division. Choice A ('S phase') is incorrect as the S phase is part of the cell cycle where DNA is replicated. Choice B ('interphase') is also incorrect as interphase is the phase where the cell prepares for division. Choice C ('mitosis') is incorrect as mitosis is a process where a diploid cell divides to produce two identical diploid daughter cells, maintaining the chromosome number.

3. What are saturated fats saturated with?

Correct answer: A

Rationale: Saturated fats are saturated with hydrogen atoms. This means that each carbon atom in the fatty acid chains forming saturated fats is bonded to as many hydrogen atoms as possible. This saturation results in the fatty acid chains being straight and closely packed together, making saturated fats solid at room temperature. Choice B (Carbon atoms), C (Oxygen atoms), and D (Nitrogen atoms) are incorrect because saturated fats are specifically saturated with hydrogen atoms, not carbon, oxygen, or nitrogen atoms.

4. Which of the following is not a product of the Krebs cycle?

Correct answer: B

Rationale: The correct answer is B: oxygen. Oxygen is not a product of the Krebs cycle. During the Krebs cycle, carbon dioxide, adenosine triphosphate (ATP), and energy carriers like NADH and FADH2 are produced. Carbon dioxide is a byproduct of the cycle, ATP is a form of energy produced, and energy carriers play a crucial role in transferring energy within the cell. Therefore, oxygen is the only option that is not a product of the Krebs cycle, making it the correct answer.

5. The force per unit area exerted against a surface by the weight of air above that surface in the Earth's atmosphere is the ______.

Correct answer: A

Rationale: Atmospheric pressure is the correct term for the force per unit area exerted against a surface by the weight of air above that surface in the Earth's atmosphere. It is commonly measured in units such as pascals, millibars, or inches of mercury. Barometric density and aneroid pressure are not accurate descriptions for this phenomenon. Barometric density refers to the density of the atmosphere at a particular location, while aneroid pressure is linked to a type of barometer but not a comprehensive term for the force exerted by the weight of air.

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