HESI A2
Biology HESI A2 2024
1. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
2. Which of these molecules contains glucose?
- A. Proteins
- B. Lipids
- C. Nucleic acids
- D. Carbohydrates
Correct answer: D
Rationale: Glucose is a type of simple sugar and is classified as a carbohydrate. It is commonly found in various carbohydrate-containing foods such as fruits, vegetables, grains, and sugary snacks. Therefore, the molecule containing glucose would be a carbohydrate, making choice D the correct answer. Proteins (choice A) are made up of amino acids, lipids (choice B) are fats, and nucleic acids (choice C) are DNA and RNA, none of which contain glucose.
3. Select the option that best shows complementary base pairing in DNA:
- A. A and G
- B. A and C
- C. A and A
- D. A and T
Correct answer: D
Rationale: The correct answer is D. A purine (A) must pair with a pyrimidine (T) in DNA. This eliminates options A and C as they do not follow the rule of complementary base pairing. Adenine (A) always pairs with thymine (T) due to their specific shape and bonding properties in DNA structure. Choice B is incorrect because adenine does not pair with cytosine in DNA.
4. What is the process of cell division that results in two daughter cells with identical genetic material?
- A. Mitosis
- B. Meiosis
- C. Binary Fission
- D. Budding
Correct answer: A
Rationale: The correct answer is A, Mitosis. Mitosis is the process of cell division in which a cell divides and produces two daughter cells that are genetically identical to the parent cell. Choice B, Meiosis, is a type of cell division that produces gametes with half the number of chromosomes. Choice C, Binary Fission, is a form of asexual reproduction in single-celled organisms. Choice D, Budding, is a form of asexual reproduction where a new organism develops from an outgrowth or bud on the parent.
5. Why is DNA important for the metabolic activities of the cell?
- A. It initiates cellular mitosis.
- B. It provides cell wall stability.
- C. It increases glucose absorption.
- D. It controls the synthesis of enzymes.
Correct answer: D
Rationale: DNA is important for the metabolic activities of the cell because it controls the synthesis of enzymes. Enzymes are essential for catalyzing metabolic reactions in the cell. Choices A, B, and C are incorrect because DNA is not directly involved in cellular mitosis, cell wall stability, or glucose absorption.
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