imagine that two parents both carry the recessive gene for cystic fibrosis any homozygous recessive offspring will manifest the disease what percentag
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HESI A2

Biology HESI A2 2024

1. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?

Correct answer: B

Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.

2. Which statement is true of enzymes?

Correct answer: B

Rationale: The correct answer is B: Enzymes are made from proteins. Enzymes are biological molecules that act as catalysts to speed up chemical reactions in living organisms. While the majority of enzymes are proteins, a few are made from RNA. The statement that enzymes are made from lipids (choice A) is incorrect. Enzymes do not form double chains of DNA (choice C) as their primary function is not related to DNA structure. Additionally, enzymes themselves do not bind with catalysts (choice D); instead, they act as catalysts to facilitate reactions.

3. What is the composition of the plasma membrane?

Correct answer: B

Rationale: The plasma membrane is composed of lipids, proteins, and carbohydrates. While proteins are an essential component of the plasma membrane, it is not the only constituent. Carbohydrates and lipids also play crucial roles in the structure and function of the plasma membrane. Nucleotides are not part of the primary structural components of the plasma membrane, making this choice incorrect.

4. What are plasma membranes mostly made of?

Correct answer: C

Rationale: The correct answer is C: Lipids. Plasma membranes are primarily composed of lipids, specifically phospholipids, which form a lipid bilayer. While proteins are also an essential component of plasma membranes, they are not the primary constituent. Carbohydrates are present on the outer surface of the membrane but are not the main structural component. Nucleotides are the building blocks of nucleic acids like DNA and RNA and are not the main constituents of plasma membranes.

5. Which two bases are purines?

Correct answer: A

Rationale: Adenine (A) and guanine (G) are the two bases that are purines. Purines are characterized by a double-ring structure containing two carbon rings, distinguishing them from pyrimidines. Adenine and guanine are purines because they possess this unique double-ring structure. Therefore, choices A and D, adenine and guanine, respectively, are the correct answers. Choices B and C, cytosine and thymine, are pyrimidines and do not exhibit the double-ring structure characteristic of purines.

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