HESI A2
Biology HESI A2 2024
1. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
2. What is the most important component of the cell, contributing to protection, communication, and the passage of substances?
- A. Cytoplasm
- B. Cell Membrane
- C. Cytoskeleton
- D. Vacuole
Correct answer: B
Rationale: The cell membrane is the correct answer. It is the most important component of the cell as it provides protection, facilitates communication, and regulates the passage of substances in and out of the cell. The cytoplasm (Choice A) is the gel-like substance within the cell that holds organelles, but it is not primarily responsible for the functions mentioned in the question. The cytoskeleton (Choice C) provides structural support to the cell but is not directly involved in protection, communication, or substance passage. Vacuoles (Choice D) are responsible for storage and maintaining turgor pressure but do not play a primary role in the functions specified in the question.
3. Which organism reproduces via spore formation?
- A. Shelf fungus
- B. Lemon tree
- C. Smallmouth bass
- D. Staphylococcus
Correct answer: A
Rationale: The correct answer is A, Shelf fungus. Shelf fungus reproduces via spore formation. Spores are tiny, reproductive cells that are released into the environment to be carried by air or water, allowing the fungus to spread and reproduce. The other choices are incorrect because Lemon tree reproduces via seeds, Smallmouth bass reproduce sexually through the fertilization of eggs by sperm, and Staphylococcus bacteria reproduce by binary fission, dividing into two identical daughter cells.
4. What is the purpose of the mitochondria?
- A. Control the cell
- B. Create energy
- C. Create proteins
- D. Package waste for removal
Correct answer: B
Rationale: The correct answer is B: Create energy. The primary purpose of the mitochondria is to generate energy for the cell. Mitochondria are known as the 'powerhouses' of the cell because they produce ATP (adenosine triphosphate), which is the energy currency used by cells to carry out various functions and processes. Choice A is incorrect as the mitochondria do not control the cell but rather produce energy. Choice C is incorrect as protein synthesis primarily occurs in the ribosomes. Choice D is incorrect as packaging waste for removal is a function associated with lysosomes, not mitochondria.
5. Which organelle is responsible for organizing protein synthesis?
- A. Nucleus
- B. Ribosome
- C. Lysosome
- D. Vacuole
Correct answer: B
Rationale: The correct answer is B: Ribosome. Ribosomes are responsible for organizing protein synthesis by assembling amino acids. They are the cellular machinery where proteins are synthesized. The other choices, such as the nucleus, lysosome, and vacuole, do not directly participate in protein synthesis. The nucleus contains DNA and controls cell activities, the lysosome is involved in digestion and waste removal, and the vacuole is responsible for storage and maintaining cell turgor pressure.
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