HESI A2
Biology HESI A2 2024
1. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
2. Two organisms live in a relationship from which both benefit. What is this called?
- A. Mutualism
- B. Parasitism
- C. Commensalism
- D. Competition
Correct answer: A
Rationale: Mutualism is a type of symbiotic relationship between two organisms in which both parties benefit from the association. It is a mutually beneficial interaction where both organisms gain something valuable, such as food, protection, or some other resource. This contrasts with parasitism, where one organism benefits at the expense of the other, commensalism, where one organism benefits while the other is unaffected, and competition, where both organisms are negatively affected by their interaction.
3. What is the initial step in the metabolism of food to cellular energy?
- A. Citric Acid Cycle
- B. Glycolysis
- C. Electron Transport Chain
- D. Photosynthesis
Correct answer: B
Rationale: The correct answer is B: Glycolysis. Glycolysis is the initial step in the metabolism of food to cellular energy. During glycolysis, glucose is broken down into pyruvate, generating ATP and NADH. Choices A, C, and D are incorrect because the Citric Acid Cycle and Electron Transport Chain occur later in cellular respiration, while Photosynthesis is the process by which plants convert light energy into chemical energy.
4. When the genotype consists of a dominant and a recessive allele, the phenotype will be like the _ allele.
- A. Dominant
- B. Recessive
- C. Both
- D. Neither
Correct answer: A
Rationale: When the genotype consists of a dominant and a recessive allele, the phenotype will be like the dominant allele. This is because dominant alleles typically mask the expression of recessive alleles. Therefore, the dominant allele will be expressed in the phenotype in most basic cases. The recessive allele will only be expressed phenotypically if the individual is homozygous recessive. Choice B, 'Recessive,' is incorrect because the phenotype will not be like the recessive allele in this case. Choice C, 'Both,' is incorrect because in simple dominant-recessive inheritance, the dominant allele will overshadow the recessive allele. Choice D, 'Neither,' is incorrect as the phenotype will resemble the dominant allele.
5. Which bacteria are spherical in shape?
- A. Clostridia
- B. Bacilli
- C. Spirilla
- D. Cocci
Correct answer: D
Rationale: The correct answer is D, Cocci. Bacteria that are spherical in shape are known as cocci. They can be found in various arrangements such as clusters, chains, or pairs. Examples of cocci bacteria include Staphylococcus aureus and Streptococcus pneumoniae. Choice A, Clostridia, consists of rod-shaped bacteria. Choice B, Bacilli, refers to rod-shaped bacteria as well. Choice C, Spirilla, are spiral-shaped bacteria, not spherical.
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