imagine that two parents both carry the recessive gene for cystic fibrosis any homozygous recessive offspring will manifest the disease what percentag
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HESI A2

Biology HESI A2 2024

1. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?

Correct answer: B

Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.

2. What is the correct order of the hierarchy of levels in the biological classification of organisms?

Correct answer: A

Rationale: The correct order of the hierarchy of levels in the biological classification of organisms is Kingdom, Phylum, Class, Order, Family, Genus, and Species. This order is based on the Linnaean system of classification, with each level representing a progressively more specific grouping of organisms. Choice B is incorrect because it starts with Phylum instead of Kingdom. Choice C is incorrect as it places Order before Phylum. Choice D is incorrect because it does not follow the correct order of the biological classification hierarchy.

3. The procedure to focus an image using a compound microscope involves

Correct answer: B

Rationale: When using a compound microscope, it is essential to adjust the fine adjustment knob each time you switch to a new magnification level. The fine adjustment knob allows for precise focusing on the specimen at different magnifications, ensuring a clear and sharp image. The coarse adjustment knob is typically used only at the lower magnification settings to bring the image into view roughly. Adjusting the stage may be necessary based on the size and thickness of the specimen, but it does not need to be done every time a new magnification is selected. Therefore, option B is the correct choice as it focuses on the key aspect of precise focusing during magnification changes.

4. What is necessary for active transport through a membrane to take place?

Correct answer: D

Rationale: Active transport through a membrane requires energy in the form of ATP (adenosine triphosphate). ATP provides the necessary energy for the transport proteins to move molecules against the concentration gradient, from an area of lower concentration to higher concentration. This process is essential for maintaining cellular functions and regulating the internal environment of a cell. Glucose, oxygen, and sodium are important molecules involved in various cellular processes, but they are not the primary energy source required for active transport across membranes. Therefore, the correct answer is ATP.

5. Humans, or Homo sapiens, are part of the family ___________.

Correct answer: B

Rationale: Humans, or Homo sapiens, are part of the family Hominidae, which includes great apes such as gorillas, chimpanzees, and orangutans. This family belongs to the order Primates within the class Mammalia. Choice A (Animalia) refers to the animal kingdom, not the family of humans. Choice C (Mammalia) is the class to which the family Hominidae belongs, not the family itself. Choice D (Chordata) is the phylum to which humans and other animals with a notochord belong, not the specific family.

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