imagine that two parents both carry the recessive gene for cystic fibrosis any homozygous recessive offspring will manifest the disease what percentag
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HESI A2

Biology HESI A2 2024

1. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?

Correct answer: B

Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.

2. In order, from lower to upper, the layers of the atmosphere are:

Correct answer: B

Rationale: The correct order of the layers of the atmosphere, from lower to upper, is troposphere, stratosphere, mesosphere, thermosphere, exosphere. The troposphere is the lowest layer where weather phenomena occur. The stratosphere contains the ozone layer, which absorbs and scatters the solar ultraviolet radiation. The mesosphere is where most meteorites burn up upon entering the Earth's atmosphere. The thermosphere is characterized by high temperatures due to the absorption of solar radiation. The exosphere is the outermost layer where the atmosphere transitions into space. Therefore, option B is the correct sequence, as it reflects the ascending order of the Earth's atmospheric layers.

3. What is the primary function of the endoplasmic reticulum in a cell?

Correct answer: D

Rationale: The endoplasmic reticulum's primary function is the transport of materials within the cell. It acts as a network of membranes to assist in the transportation of proteins and other substances throughout the cell. Choice A, 'Energy production,' is incorrect because the endoplasmic reticulum is not directly involved in energy production. Choice B, 'Protein synthesis,' is incorrect as protein synthesis mainly occurs in ribosomes, although the endoplasmic reticulum is involved in modifying and transporting proteins. Choice C, 'Waste removal,' is also incorrect as waste removal is primarily handled by other organelles like lysosomes and peroxisomes.

4. Which of the following describes the situation where one allele takes a different form from another in a gene?

Correct answer: B

Rationale: Heterozygous is the term used to describe the genotype of an individual with two different alleles for a specific gene. In this case, one allele takes a different form from another, resulting in genetic diversity and variation in trait expression. The other choices are incorrect: 'phenotype' refers to the observable traits of an organism, 'homolog' typically refers to chromosomes that are similar in structure, and 'homozygous' describes the genotype where both alleles for a gene are the same.

5. What is necessary for active transport through a membrane to take place?

Correct answer: D

Rationale: Active transport through a membrane requires energy in the form of ATP (adenosine triphosphate). ATP provides the necessary energy for the transport proteins to move molecules against the concentration gradient, from an area of lower concentration to higher concentration. This process is essential for maintaining cellular functions and regulating the internal environment of a cell. Glucose, oxygen, and sodium are important molecules involved in various cellular processes, but they are not the primary energy source required for active transport across membranes. Therefore, the correct answer is ATP.

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