HESI A2
Biology HESI A2 2024
1. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
2. What is the process of cell division that results in two daughter cells with identical genetic material?
- A. Mitosis
- B. Meiosis
- C. Binary Fission
- D. Budding
Correct answer: A
Rationale: The correct answer is A, Mitosis. Mitosis is the process of cell division in which a cell divides and produces two daughter cells that are genetically identical to the parent cell. Choice B, Meiosis, is a type of cell division that produces gametes with half the number of chromosomes. Choice C, Binary Fission, is a form of asexual reproduction in single-celled organisms. Choice D, Budding, is a form of asexual reproduction where a new organism develops from an outgrowth or bud on the parent.
3. What happens during the S phase of the cell cycle?
- A. Chromosomes are duplicated.
- B. Cell growth occurs.
- C. DNA is synthesized.
- D. DNA is destroyed.
Correct answer: A
Rationale: During the S phase of the cell cycle, chromosomes are duplicated. This is a critical step in cell division as each chromosome is replicated to ensure that the resulting daughter cells receive an identical set of genetic information. Choices B, C, and D are incorrect because cell growth primarily occurs in the G1 phase, DNA synthesis happens during the S phase, and DNA destruction does not occur during any phase of the cell cycle.
4. How is the plasma membrane arranged?
- A. In a single layer made of proteins
- B. In a double layer made of proteins
- C. In a single layer of phospholipids
- D. In a double layer of phospholipids
Correct answer: D
Rationale: The plasma membrane is arranged in a double layer of phospholipids, known as a phospholipid bilayer. This structure consists of two layers of phospholipid molecules with hydrophilic heads facing the exterior and hydrophobic tails facing the interior, providing a semipermeable barrier for the cell. Choice A is incorrect because the plasma membrane is not made of a single layer of proteins. Choice B is incorrect as the double layer is composed of phospholipids, not proteins. Choice C is incorrect as the plasma membrane is not made of a single layer of phospholipids but rather a double layer.
5. What cycle is the sequence of reactions by which most living cells generate energy during aerobic respiration?
- A. Calvin Cycle
- B. Krebs Cycle
- C. Photosynthesis
- D. Fermentation
Correct answer: B
Rationale: The Krebs Cycle is the correct answer. It is a series of reactions occurring in the mitochondria and is a crucial part of aerobic respiration. The Calvin Cycle is a part of photosynthesis, not respiration, making choice A incorrect. Photosynthesis (choice C) is the process by which plants, algae, and some bacteria convert light energy into chemical energy. Fermentation (choice D) is an anaerobic process that does not require oxygen and is not the primary energy-generating pathway during aerobic respiration, so it is incorrect.
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