HESI A2
Biology HESI A2 2024
1. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
2. How does asexual reproduction differ from sexual reproduction?
- A. asexual reproduction results in all cells being identical to the original cell; sexual reproduction results in half of the cells being identical to the original cell
- B. asexual reproduction results in two cells that contribute genetic material to daughter cells, resulting in significantly greater variation
- C. sexual reproduction involves two cells that contribute genetic material to daughter cells, resulting in significantly greater variation
- D. sexual reproduction involves one cell that yields all cells produced to be identical
Correct answer: C
Rationale: Sexual reproduction involves two cells (gametes) that contribute genetic material to daughter cells, resulting in significantly greater genetic variation in the offspring. This genetic variation is essential for evolution and adaptation to environmental changes. In contrast, asexual reproduction involves one cell dividing to produce offspring that are genetically identical to the parent cell. Choice A is incorrect because sexual reproduction does not result in half of the cells being identical to the original cell; it involves two cells contributing genetic material. Choice B is incorrect because asexual reproduction does not result in significantly greater variation; it produces genetically identical offspring. Choice D is incorrect because sexual reproduction involves two cells contributing genetic material, not one cell yielding all identical cells.
3. Which of the following animals would have the least energy efficiency in nutrient consumption?
- A. Cow
- B. Caterpillar
- C. Coyote
- D. Cricket
Correct answer: A
Rationale: Cows are ruminant animals that have multiple stomachs and require large amounts of food to digest and convert into energy. They have lower energy efficiency compared to insects like caterpillars, coyotes, and crickets, which have more efficient nutrient consumption processes. The digestive system and metabolic functions of cows result in them having the least energy efficiency in nutrient consumption among the given choices. Caterpillars, coyotes, and crickets have more efficient nutrient consumption processes, making them more energy-efficient than cows.
4. Which of the following is true of homozygous traits?
- A. They are haploid
- B. They are denoted AA
- C. They are denoted aa
- D. They are denoted Aa
Correct answer: B
Rationale: Homozygous traits have two identical forms of the gene, either both dominant (AA) or both recessive (aa). Therefore, choices B and C are true for homozygous traits. Choice A is incorrect because being haploid refers to having a single set of chromosomes, not necessarily homozygous traits. Choice D is incorrect as homozygous traits have identical alleles, so they are not denoted as Aa.
5. How should a researcher test the hypothesis that practicing yoga reduces blood pressure?
- A. Record the blood pressure of one male and one female participant before and after participating in a yoga class.
- B. Divide 30 female participants into two groups with similar average blood pressure; test each participant’s blood pressure after participating in a yoga class.
- C. Divide 30 female participants into two groups with similar average blood pressure; have one group watch television for an hour while the other takes a yoga class, record each participant’s blood pressure after the hour. Repeat daily for two weeks.
- D. Start with 15 men and 15 women; have the men watch television for an hour while the women take a yoga class, record each participant’s blood pressure after the hour. Reverse, having the men take a yoga class while the women watch television.
Correct answer: B
Rationale: Option B is the most appropriate way to test the hypothesis that practicing yoga reduces blood pressure. By dividing 30 female participants into two groups with similar average blood pressure levels and testing each participant's blood pressure after participating in a yoga class, the researcher can effectively evaluate the impact of yoga on blood pressure. This design allows for a comparison between the two groups, helping to isolate the effects of yoga practice on blood pressure. Option A only involves one male and one female participant, which may not provide a representative sample. Option C introduces an additional variable of watching television, which could confound the results. Option D lacks consistency in the experimental design by switching the activities between men and women, making it difficult to attribute any observed changes solely to yoga practice.
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