imagine that two parents both carry the recessive gene for cystic fibrosis any homozygous recessive offspring will manifest the disease what percentag
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HESI A2

Biology HESI A2 2024

1. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?

Correct answer: B

Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.

2. Which is not one of the raw materials needed for cellular respiration?

Correct answer: C

Rationale: Water is not one of the raw materials needed for cellular respiration. The essential raw materials for cellular respiration include glucose (which is broken down to produce energy), oxygen, and ADP (adenosine diphosphate) and phosphate (which are necessary for the formation of ATP, the energy currency of cells). While water is crucial for many cellular processes and makes up a significant portion of cells, it is not directly involved as a raw material in the cellular respiration process.

3. How does an enzyme work on a chemical reaction that occurs in a substrate?

Correct answer: B

Rationale: Enzymes are biological catalysts that facilitate chemical reactions by lowering the activation energy required for the reaction to occur. This allows the reaction to proceed more quickly and efficiently. Enzymes do not change the overall outcome of the reaction, but they significantly increase the rate at which it takes place. Therefore, choice B, 'An enzyme speeds up the chemical reaction,' is the correct answer. Choices A, C, and D are incorrect because enzymes do not slow down, have no effect, or stop chemical reactions; instead, they accelerate the process by lowering the activation energy.

4. Why are bacteria and blue-green algae often classified together?

Correct answer: B

Rationale: Bacteria and blue-green algae (cyanobacteria) are often classified together because they are both prokaryotes. Prokaryotes are unicellular organisms that lack a membrane-bound nucleus and other membrane-bound organelles. This characteristic distinguishes them from eukaryotic organisms, which have these membrane-bound structures. Choice A is incorrect because gymnosperms are seed-producing plants with naked seeds, not bacteria or blue-green algae. Choice C is incorrect because being an autotroph (able to produce its own food) is not a reason for classifying them together. Choice D is incorrect because not all bacteria and blue-green algae are pathogens; many of them are beneficial or neutral to other organisms.

5. What happens during anaphase?

Correct answer: A

Rationale: During anaphase, the sister chromatids, joined at the centromere, separate and move towards opposite ends of the spindle apparatus. This movement ensures that each daughter cell receives an identical set of chromosomes. Choice B is incorrect as the disintegration of the nuclear membrane and nucleoli occurs during prophase. Choice C is incorrect as chromatids align at the center of the spindle during metaphase, not anaphase. Choice D is incorrect as the formation of the nuclear membrane and nucleoli occurs during telophase, not anaphase.

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