HESI A2
HESI A2 Biology Practice Test 2024
1. Where is the genetic information of a eukaryotic cell stored?
- A. Mitochondria
- B. Nucleus
- C. Golgi Apparatus
- D. Cytoplasm
Correct answer: B
Rationale: The correct answer is B: Nucleus. In eukaryotic cells, genetic information (DNA) is stored in the nucleus. This organelle acts as the control center of the cell, housing the DNA and regulating gene expression. Choices A, C, and D are incorrect because the genetic information is not stored in the mitochondria, Golgi Apparatus, or cytoplasm. The mitochondria are responsible for energy production, the Golgi Apparatus is involved in protein processing and packaging, and the cytoplasm is where various cellular activities take place, but none of these organelles store the genetic information.
2. During which phase of mitosis do the chromosomes align in the center of the cell?
- A. Prophase
- B. Metaphase
- C. Telophase
- D. Anaphase
Correct answer: B
Rationale: The correct answer is Metaphase. During Metaphase, the chromosomes line up along the center of the cell's equator, forming the metaphase plate. This alignment ensures that during the subsequent phase, Anaphase, the sister chromatids can separate and move towards opposite poles. Prophase is the initial phase of mitosis where chromosomes condense and the nuclear envelope breaks down. Telophase is the final phase of mitosis where two new nuclei form.
3. Which of the following is the best example of a hypothesis?
- A. Dogs like treats
- B. Red is the best color
- C. If I eat 100 donuts, then I will feel sick
- D. If a plant is exposed to red light, then it will show less growth than natural light
Correct answer: D
Rationale: Option D is the best example of a hypothesis because it presents a clear cause-and-effect relationship that can be tested through experimentation. It follows the format of 'If [cause], then [effect]' which is characteristic of a hypothesis in scientific research. The statement is specific, testable, and does not rely on personal opinions or biases, making it a strong and valid hypothesis. Choices A, B, and C do not follow the structure of a hypothesis as they lack the cause-and-effect relationship that can be tested through experimentation. They are more like statements or opinions rather than hypotheses.
4. Which gives the order of four taxonomic categories from least to most specific?
- A. Kingdom, phylum, class, order
- B. Kingdom, phylum, order, class
- C. Kingdom, order, phylum, class
- D. Kingdom, class, order, phylum
Correct answer: A
Rationale: The correct order of the four taxonomic categories from least to most specific is Kingdom, phylum, class, and order. This sequence adheres to the hierarchical system of classification where organisms are grouped based on shared characteristics, becoming more specific as you move from Kingdom to order. Choice B is incorrect as the order of 'order' and 'class' is swapped. Choice C is incorrect as 'order' precedes 'phylum' instead of following it. Choice D is incorrect as 'class' should come before 'order'.
5. Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. In an example of an unaffected father and a female carrier who have two daughters and two sons, which is the predicted outcome?
- A. Both daughters will carry the disease.
- B. Both sons will carry the disease.
- C. One daughter may have the disease.
- D. One son may have the disease.
Correct answer: C
Rationale: Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. Since the father is unaffected and does not carry the disease, he must have a normal X chromosome. The mother is a carrier, which means she has one normal X chromosome and one X chromosome with the disease allele. The daughters will inherit one X chromosome from each parent; one would be normal, and the other has a chance of carrying the disease allele. So, there is a 50% chance that one daughter may have the disease, as she could inherit the X chromosome with the disease allele. The sons will inherit the Y chromosome from the father and the X chromosome from the mother, so they will not be affected by the disease. Therefore, the predicted outcome is that one daughter may have the disease, while the sons will not carry the disease. This rules out choices A, B, and D.
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