HESI A2
Biology HESI A2 Practice Test
1. Why does cellular respiration happen?
- A. Cells can copy DNA
- B. Cells can breathe
- C. Cells can convert nutrients to energy
- D. Cells can divide
Correct answer: C
Rationale: Cellular respiration is the process through which cells break down nutrients such as glucose to produce ATP (adenosine triphosphate), the energy currency of the cell. This process allows cells to extract energy from food molecules and use it for various cellular activities and functions. Choices A, B, and D are incorrect because cellular respiration is specifically about converting nutrients to energy, not about DNA copying, breathing, or cell division.
2. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
3. How are molecules of water bonded to each other?
- A. Ionic
- B. Covalent
- C. Hydrogen
- D. Molecular
Correct answer: C
Rationale: Water molecules are bonded to each other by 'hydrogen' bonds. These bonds are not as strong as covalent bonds, which hold the atoms within each water molecule together (Choice B). Ionic bonds (Choice A) involve the transfer of electrons between atoms, which is not the case in water molecules. The term 'molecular' (Choice D) is too general and doesn't specifically describe the type of bond between water molecules.
4. Why does cytokinesis happen?
- A. DNA can duplicate
- B. Organelles can convert energy
- C. Bacteria can be killed
- D. Daughter cells can divide
Correct answer: D
Rationale: Cytokinesis happens at the end of mitosis to physically separate the newly formed daughter cells. This allows the cell to divide into two separate daughter cells, each containing a complete set of genetic material (DNA) and organelles. The purpose of cytokinesis is to ensure that each daughter cell receives the necessary components to function independently. Choices A, B, and C are incorrect because cytokinesis does not directly involve DNA duplication, organelles converting energy, or killing bacteria.
5. Which names a final step in protein synthesis?
- A. DNA unzips.
- B. Amino acids bond.
- C. Transfer RNA bonds to messenger RNA.
- D. Messenger RNA moves to ribosomes.
Correct answer: B
Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
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