HESI A2
HESI A2 Practice Test Biology
1. Which organelle is responsible for organizing protein synthesis?
- A. Nucleus
- B. Ribosome
- C. Lysosome
- D. Vacuole
Correct answer: B
Rationale: The correct answer is B: Ribosome. Ribosomes are responsible for organizing protein synthesis by assembling amino acids. They are the cellular machinery where proteins are synthesized. The other choices, such as the nucleus, lysosome, and vacuole, do not directly participate in protein synthesis. The nucleus contains DNA and controls cell activities, the lysosome is involved in digestion and waste removal, and the vacuole is responsible for storage and maintaining cell turgor pressure.
2. Why is the nucleus important in a cell?
- A. It stores the DNA
- B. It supports the cell
- C. It makes protein
- D. It makes energy out of food
Correct answer: A
Rationale: The nucleus is important in a cell because it stores the DNA, which contains the genetic information necessary for the cell's function and replication. This genetic material controls the cell's activities and characteristics. Choices B, C, and D are incorrect because supporting the cell, making proteins, and producing energy are functions typically associated with other cell organelles like the cytoskeleton, ribosomes, and mitochondria, respectively.
3. During which phase of cell division do the chromosomes replicate?
- A. Prophase
- B. Interphase
- C. Anaphase
- D. Telophase
Correct answer: B
Rationale: Chromosomes replicate during the interphase of the cell cycle. Interphase is the phase where the cell prepares for division by undergoing various activities such as growth, DNA replication, and protein synthesis. During DNA replication in interphase, each chromosome in the cell is duplicated to form two sister chromatids, which are then separated during cell division. Prophase is the phase where the chromosomes condense, and the nuclear envelope breaks down. Anaphase is the phase where sister chromatids are pulled apart towards opposite poles of the cell. Telophase is the phase where the nuclear envelope reforms, and chromosomes begin to decondense.
4. During which phase of mitosis does the nuclear envelope disintegrate?
- A. Prophase
- B. Prophase
- C. Prometaphase
- D. Metaphase
Correct answer: C
Rationale: During the prometaphase stage of mitosis, the nuclear envelope disintegrates. This allows the condensed chromosomes to move towards the center of the cell, preparing for their alignment along the metaphase plate. The breakdown of the nuclear envelope is a crucial step in mitosis to ensure the proper segregation of genetic material into daughter cells. Choices A, B, and D are incorrect as the nuclear envelope disintegration specifically occurs during the prometaphase stage, not in prophase or metaphase.
5. In the scientific process, which of the following is a statement or explanation of certain events or happenings?
- A. hypothesis
- B. observation
- C. experiment
- D. conclusion
Correct answer: A
Rationale: A hypothesis is a statement or explanation of certain events or phenomena based on observations and prior knowledge. It is a testable prediction that guides the scientific investigation process. By formulating a hypothesis, scientists can make predictions and design experiments to gather data and test the validity of the hypothesis. Observations (choice B) involve gathering information through the senses. Experiments (choice C) are procedures carried out to support or refute a hypothesis. Conclusions (choice D) are deductions made based on the results of experiments and observations, but they are not the initial statement or explanation of events or happenings.
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