HESI A2
HESI A2 Biology 2024
1. How many pairs of homologous chromosomes do humans have?
- A. 13
- B. 23
- C. 26
- D. 46
Correct answer: D
Rationale: The correct answer is D: 46. Humans have 23 pairs of chromosomes, which include 22 pairs of autosomes and 1 pair of sex chromosomes. Homologous chromosomes are pairs of chromosomes that contain the same genes, one from each parent. Therefore, humans have a total of 46 chromosomes, with 23 pairs of homologous chromosomes. Choices A, B, and C are incorrect as they do not represent the total number of chromosomes in humans or the number of pairs of homologous chromosomes.
2. Which of the following arrangement is seen in the plasma membrane?
- A. Lipids with embedded proteins
- B. An outer lipid layer and an inner lipid layer
- C. Proteins embedded in lipid bilayer
- D. Altering protein and lipid layers
Correct answer: C
Rationale: The correct arrangement seen in the plasma membrane is proteins embedded in the lipid bilayer. The plasma membrane is composed of a lipid bilayer with embedded proteins. These proteins perform various functions such as transport, signaling, and structural support within the cell membrane. This arrangement allows for the selective permeability of the membrane and facilitates communication between the cell and its environment. Choices A, B, and D are incorrect because the primary arrangement in the plasma membrane involves proteins being embedded in the lipid bilayer, not lipids with embedded proteins, an outer and inner lipid layer, or altering protein and lipid layers.
3. How many chromosomes do sperm and egg produce in meiosis?
- A. 23
- B. 46
- C. 25
- D. 50
Correct answer: A
Rationale: During meiosis, sperm and egg cells produce half the number of chromosomes found in somatic cells. Each contributes 23 chromosomes, which combine to form a zygote with a total of 46 chromosomes. Choice B (46) is incorrect because this is the number of chromosomes produced in mitosis, not meiosis. Choices C (25) and D (50) are also incorrect as they do not align with the chromosome count in sex cells during meiosis.
4. In a strand of DNA, you would expect to see adenine paired with ___________.
- A. cytosine
- B. uracil
- C. thymine
- D. guanine
Correct answer: C
Rationale: In a strand of DNA, adenine always pairs with thymine through two hydrogen bonds. This pairing is a fundamental aspect of DNA structure, where adenine and thymine complement each other in the double helix. Choice A (cytosine) is incorrect because adenine does not pair with cytosine in DNA. Choice B (uracil) is incorrect as uracil is found in RNA, not DNA. Choice D (guanine) is incorrect as guanine pairs with cytosine, not adenine, in DNA.
5. Which is true of gametes?
- A. They are diploid cells
- B. They are haploid cells
- C. They are somatic
- D. A & C are true
Correct answer: B
Rationale: Gametes are sex cells (sperm and eggs) that are involved in sexual reproduction. They are haploid cells, meaning they have half the number of chromosomes (n) compared to diploid cells. This is necessary for the formation of a diploid zygote when two gametes unite during fertilization. Somatic cells are non-reproductive cells in the body, so they are not gametes. Choice A is incorrect because gametes are not diploid but haploid. Choice C is incorrect because gametes are not somatic cells.
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