how many pairs of homologous chromosomes do humans have
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HESI A2

HESI A2 Biology 2024

1. How many pairs of homologous chromosomes do humans have?

Correct answer: D

Rationale: The correct answer is D: 46. Humans have 23 pairs of chromosomes, which include 22 pairs of autosomes and 1 pair of sex chromosomes. Homologous chromosomes are pairs of chromosomes that contain the same genes, one from each parent. Therefore, humans have a total of 46 chromosomes, with 23 pairs of homologous chromosomes. Choices A, B, and C are incorrect as they do not represent the total number of chromosomes in humans or the number of pairs of homologous chromosomes.

2. Which component of the cell contributes to the protection, communication, and passage of substances into and out of the cell?

Correct answer: B

Rationale: The correct answer is the cell membrane. The cell membrane is responsible for protecting the cell, facilitating communication with the external environment, and regulating the passage of substances into and out of the cell. The nucleus (Choice A) is the control center of the cell and houses the genetic material but is not primarily involved in these functions. The endoplasmic reticulum (Choice C) is involved in protein synthesis and lipid metabolism, not primarily in protection or communication. The cytoplasm (Choice D) is the gel-like substance that fills the cell but does not specifically contribute to protection, communication, or substance passage.

3. How should a researcher test the hypothesis that a particular species of bird vocalizes most in the hours around dawn?

Correct answer: C

Rationale: Observing a flock of the birds in the wild and recording them in predawn and postdawn hours every day for six months would be the best way to test the hypothesis that a particular species of bird vocalizes most in the hours around dawn. This method allows for consistent monitoring of the birds during specific times of interest over an extended period, providing a comprehensive dataset to accurately analyze the vocalization patterns. Options A and B do not focus specifically on dawn hours, making them less suitable for testing the hypothesis. Option D introduces a comparison with other species, which is unnecessary and distracts from the main objective of studying the vocalization pattern of the particular bird species around dawn.

4. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?

Correct answer: B

Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.

5. What kind of bond connects sugar and phosphate in DNA?

Correct answer: C

Rationale: Sugar and phosphate are indeed connected by covalent bonds in DNA. Covalent bonds involve the sharing of electrons between atoms, which is essential for forming the backbone of the DNA molecule. Hydrogen bonds (Choice A) are important in holding the nitrogenous bases together in the DNA double helix but do not connect sugar and phosphate. Ionic bonds (Choice B) involve the transfer of electrons between atoms and are not the primary bond connecting sugar and phosphate in DNA. 'Overt' (Choice D) is not a type of chemical bond and is an incorrect distractor.

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