HESI A2
HESI A2 Biology 2024
1. How many pairs of homologous chromosomes do humans have?
- A. 13
- B. 23
- C. 26
- D. 46
Correct answer: D
Rationale: The correct answer is D: 46. Humans have 23 pairs of chromosomes, which include 22 pairs of autosomes and 1 pair of sex chromosomes. Homologous chromosomes are pairs of chromosomes that contain the same genes, one from each parent. Therefore, humans have a total of 46 chromosomes, with 23 pairs of homologous chromosomes. Choices A, B, and C are incorrect as they do not represent the total number of chromosomes in humans or the number of pairs of homologous chromosomes.
2. Select the strand of DNA that would match this segment: ACTTGCA
- A. TGAACGT
- B. GACCATG
- C. ACTTGCA
- D. None of the above
Correct answer: A
Rationale: The correct match for the DNA segment ACTTGCA is TGAACGT. In DNA, adenine (A) always pairs with thymine (T), and cytosine (C) always pairs with guanine (G). Therefore, the complementary strand to ACTTGCA should be TGAACGT, making choice A the correct answer. Choice B (GACCATG) does not follow the base pairing rules; hence, it is incorrect. Choice C (ACTTGCA) is the original segment, not its complementary strand. Choice D is incorrect as well because a matching strand does exist.
3. A scientist needs 12 mL of a solution. They have a bottle with 12L in it. Do they have enough?
- A. Yes, they have exactly what they need
- B. Yes, they have more than what they need
- C. No, they do not have enough
- D. None of the above
Correct answer: B
Rationale: 1 liter has 1000 milliliters. To convert from milliliters to liters, the decimal point moves three places to the left. So, the bottle has 12000 mL of solution, which is a lot more than the required 12 mL. Therefore, the scientist has more than what they need. Choice A is incorrect as the bottle has more than the required amount. Choice C is incorrect as the bottle contains significantly more solution than needed. Choice D is incorrect as the scientist does have more than enough solution.
4. What is the typical result of mitosis in humans?
- A. two diploid cells
- B. two haploid cells
- C. four diploid cells
- D. four haploid cells
Correct answer: A
Rationale: The correct answer is A: two diploid cells. Mitosis is a type of cell division that results in two daughter cells, each having the same number of chromosomes as the parent cell. In humans, the typical result of mitosis is the formation of two diploid cells, not haploid or four cells. Choice B, two haploid cells, is incorrect because mitosis produces genetically identical diploid cells. Choices C and D, four diploid cells and four haploid cells, respectively, are incorrect as mitosis results in two daughter cells, not four.
5. Which names a final step in protein synthesis?
- A. DNA unzips.
- B. Amino acids bond.
- C. Transfer RNA bonds to messenger RNA.
- D. Messenger RNA moves to ribosomes.
Correct answer: B
Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
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