during which phase of mitosis does the nuclear envelope disintegrate

HESI A2

HESI A2 Biology Practice Test

1. During which phase of mitosis does the nuclear envelope disintegrate?

A. Prophase
B. Prophase
C. Prometaphase
D. Metaphase

Correct answer: C

Rationale: During the prometaphase stage of mitosis, the nuclear envelope disintegrates. This allows the condensed chromosomes to move towards the center of the cell, preparing for their alignment along the metaphase plate. The breakdown of the nuclear envelope is a crucial step in mitosis to ensure the proper segregation of genetic material into daughter cells. Choices A, B, and D are incorrect as the nuclear envelope disintegration specifically occurs during the prometaphase stage, not in prophase or metaphase.

2. Which of the following is true of the Krebs cycle?

A. It is a redox reaction involving proteins produced during glycolysis
B. It is a redox reaction involving sugars produced during glycolysis
C. Protons are passed along a gradient to produce ATP
D. It is also known as the glycolic acid cycle

Correct answer: B

Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.

3. Select the strand of DNA that would match this segment: ACTTGCA

A. TGAACGT
B. GACCATG
C. ACTTGCA
D. None of the above

Correct answer: A

Rationale: The correct match for the DNA segment ACTTGCA is TGAACGT. In DNA, adenine (A) always pairs with thymine (T), and cytosine (C) always pairs with guanine (G). Therefore, the complementary strand to ACTTGCA should be TGAACGT, making choice A the correct answer. Choice B (GACCATG) does not follow the base pairing rules; hence, it is incorrect. Choice C (ACTTGCA) is the original segment, not its complementary strand. Choice D is incorrect as well because a matching strand does exist.

4. What is the role of tRNA during protein synthesis?

A. Carries amino acids to the ribosome
B. Links nucleotides together
C. Copies DNA sequences
D. Replicates genetic material

Correct answer: A

Rationale: During protein synthesis, tRNA plays the crucial role of carrying amino acids to the ribosome. This process ensures that the correct amino acids are brought to the ribosome according to the mRNA sequence. Choice B, linking nucleotides together, refers to the role of RNA polymerase in transcription, not tRNA. Choice C, copying DNA sequences, is the function of DNA polymerase during DNA replication, while choice D, replicating genetic material, is an overarching function of DNA replication, not specific to tRNA's role in protein synthesis.

5. The renal system consists of all the organs involved in the formation and release of urine and includes the kidneys, ureters, bladder, and urethra.

A. The digestive system
B. The reproductive system
C. The renal system
D. The kidney system

Correct answer: C

Rationale: The correct term for the system involving the organs responsible for the formation and release of urine is the renal system, not the digestive or reproductive system. The kidneys, ureters, bladder, and urethra are specifically part of the renal system, which is responsible for filtering the blood to remove waste and excess fluids, producing urine, and eliminating it from the body. The other choices, the digestive system and the reproductive system, are not responsible for the formation and release of urine, making them incorrect answers.