during which phase of mitosis does the nuclear envelope disintegrate

HESI A2

HESI A2 Biology Practice Test

1. During which phase of mitosis does the nuclear envelope disintegrate?

A. Prophase
B. Prophase
C. Prometaphase
D. Metaphase

Correct answer: C

Rationale: During the prometaphase stage of mitosis, the nuclear envelope disintegrates. This allows the condensed chromosomes to move towards the center of the cell, preparing for their alignment along the metaphase plate. The breakdown of the nuclear envelope is a crucial step in mitosis to ensure the proper segregation of genetic material into daughter cells. Choices A, B, and D are incorrect as the nuclear envelope disintegration specifically occurs during the prometaphase stage, not in prophase or metaphase.

2. Why is homeostasis necessary?

A. It maintains temperature
B. It maintains pH
C. It maintains glucose levels
D. All of the above

Correct answer: D

Rationale: Homeostasis is necessary because it ensures the maintenance of a stable, relatively constant internal environment. This includes regulating various factors such as temperature, pH levels, and glucose levels to support optimal bodily functions and overall health. Choices A, B, and C are all correct as they represent key aspects of homeostasis that contribute to maintaining the body's internal balance.

3. During protein synthesis, what process creates a complementary strand of RNA from a DNA template?

A. Transcription
B. Translation
C. Transformation
D. Replication

Correct answer: A

Rationale: The correct answer is 'Transcription.' During protein synthesis, transcription is the process that creates a complementary RNA strand from a DNA template. This process involves the synthesis of mRNA using DNA as a template. Choice B, 'Translation,' is incorrect as it is the process where the genetic code carried by mRNA is decoded to produce a specific polypeptide chain. Choice C, 'Transformation,' is not related to the synthesis of RNA from a DNA template. Choice D, 'Replication,' is the process of copying DNA to produce an identical DNA molecule, not RNA.

4. Which of the following bases is not present in RNA?

A. Adenine
B. Thymine
C. Uracil
D. Cytosine

Correct answer: B

Rationale: Thymine is not present in RNA. RNA uses uracil as one of its bases, which pairs with adenine. In RNA, adenine does not pair with thymine as in DNA. Cytosine and guanine are the other two bases found in both RNA and DNA.

5. Which of the following is true of the Krebs cycle?

A. It is a redox reaction involving proteins produced during glycolysis
B. It is a redox reaction involving sugars produced during glycolysis
C. Protons are passed along a gradient to produce ATP
D. It is also known as the glycolic acid cycle

Correct answer: B

Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.