HESI A2
HESI A2 Biology Practice Test
1. During which phase of mitosis does the nuclear envelope disintegrate?
- A. Prophase
- B. Prophase
- C. Prometaphase
- D. Metaphase
Correct answer: C
Rationale: During the prometaphase stage of mitosis, the nuclear envelope disintegrates. This allows the condensed chromosomes to move towards the center of the cell, preparing for their alignment along the metaphase plate. The breakdown of the nuclear envelope is a crucial step in mitosis to ensure the proper segregation of genetic material into daughter cells. Choices A, B, and D are incorrect as the nuclear envelope disintegration specifically occurs during the prometaphase stage, not in prophase or metaphase.
2. Which of the following describes the situation where one allele takes a different form from another in a gene?
- A. phenotype
- B. heterozygous
- C. homolog
- D. homozygous
Correct answer: B
Rationale: Heterozygous is the term used to describe the genotype of an individual with two different alleles for a specific gene. In this case, one allele takes a different form from another, resulting in genetic diversity and variation in trait expression. The other choices are incorrect: 'phenotype' refers to the observable traits of an organism, 'homolog' typically refers to chromosomes that are similar in structure, and 'homozygous' describes the genotype where both alleles for a gene are the same.
3. How many different types of nucleotides are there in DNA?
- A. one
- B. two
- C. four
- D. eight
Correct answer: C
Rationale: The correct answer is 'C: four.' DNA is composed of four different types of nucleotides: adenine, thymine, guanine, and cytosine. These nucleotides pair up in specific combinations to form the genetic code. Choices 'A: one,' 'B: two,' and 'D: eight' are incorrect because DNA consists of a set of four distinct nucleotides, not one, two, or eight.
4. What is the term for the movement of ions and other molecular substances across cell membranes without the need for energy?
- A. Active Transport
- B. Passive Transport
- C. Diffusion
- D. Osmosis
Correct answer: B
Rationale: Passive transport refers to the movement of substances across cell membranes without the need for energy input. In contrast, active transport, choice A, requires energy to move substances against their concentration gradient. Diffusion, choice C, is a type of passive transport where substances move from an area of high concentration to low concentration. Osmosis, choice D, specifically refers to the movement of water molecules across a selectively permeable membrane.
5. Which of the following cell types has no nucleus?
- A. platelet
- B. red blood cell
- C. white blood cell
- D. phagocyte
Correct answer: B
Rationale: The correct answer is B, red blood cell. In humans, red blood cells do not have a nucleus. This unique feature allows them to have more space to carry oxygen efficiently. Platelets (choice A), white blood cells (choice C), and phagocytes (choice D) all have nuclei. Platelets are cell fragments, while white blood cells and phagocytes are types of immune cells that contain a nucleus for DNA and cellular functions.
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