during which phase of mitosis does the nuclear envelope disintegrate

HESI A2

HESI A2 Biology Practice Test

1. During which phase of mitosis does the nuclear envelope disintegrate?

A. Prophase
B. Prophase
C. Prometaphase
D. Metaphase

Correct answer: C

Rationale: During the prometaphase stage of mitosis, the nuclear envelope disintegrates. This allows the condensed chromosomes to move towards the center of the cell, preparing for their alignment along the metaphase plate. The breakdown of the nuclear envelope is a crucial step in mitosis to ensure the proper segregation of genetic material into daughter cells. Choices A, B, and D are incorrect as the nuclear envelope disintegration specifically occurs during the prometaphase stage, not in prophase or metaphase.

2. How many chromosomes do sperm and egg produce in meiosis?

A. 46
B. 23
C. 45
D. 24

Correct answer: B

Rationale: Sperm and egg cells undergo meiosis to form gametes with half the number of chromosomes found in somatic cells. Each sperm and egg cell produces 23 chromosomes through meiosis. Choice A is incorrect because 46 chromosomes represent the diploid number found in somatic cells. Choice C is incorrect as it is an uncommon number for chromosome production in human gametes. Choice D is incorrect as the total number of chromosomes in sperm or egg cells is 23, not 24.

3. Which of the following structures is not directly involved in translation?

A. tRNA
B. mRNA
C. ribosome
D. DNA

Correct answer: D

Rationale: The correct answer is 'D: DNA.' DNA is not directly involved in translation, which is the process of synthesizing proteins from mRNA. tRNA carries amino acids to the ribosome, mRNA provides the template for protein synthesis, and ribosomes are the cellular machinery where translation occurs. DNA's main role is in transcription, where it serves as the template for mRNA synthesis, not in translation.

4. In an example of a male with hemophilia and a female carrier, what ratio of the offspring are predicted neither to carry nor to manifest the disease?

A. 0 females : 1 male
B. 1 female : 1 male
C. 1 female : 0 males
D. 2 females : 1 male

Correct answer: D

Rationale: In this scenario, the male offspring will inherit the Y chromosome from the father and the X chromosome from the carrier mother. As a result, they will not have the hemophilia gene. The female offspring will inherit one X chromosome from the mother, which does not carry the hemophilia gene, and one X chromosome from the father, which does not exist due to the Y chromosome. Therefore, all female offspring will not carry or manifest hemophilia, resulting in a ratio of 2 females to 1 male. Choice A is incorrect because it does not account for the female offspring. Choices B and C are incorrect as they do not reflect the correct ratio based on the inheritance pattern of hemophilia.

5. What process do cells in the tip of a plant’s root undergo to increase in number?

A. Meiosis
B. Cytokinesis
C. Fractioning
D. Mitosis

Correct answer: D

Rationale: Cells in the tip of a plant's root undergo the process of mitosis to increase in number. Mitosis is a type of cell division that results in two daughter cells with the same number of chromosomes as the parent cell. This process allows for growth and maintenance of tissues in plants by producing new cells through division. Choice A, Meiosis, is incorrect as meiosis is a type of cell division that reduces the number of chromosomes in cells to produce gametes. Choice B, Cytokinesis, is incorrect as it is the division of the cytoplasm following cell division. Choice C, Fractioning, is not a biological process related to cell division.