HESI A2
Biology HESI A2 Practice Exam
1. What event occurs during telophase?
- A. The nuclear envelope disappears.
- B. Organelles double in number.
- C. Chromosomes separate.
- D. Two nuclei are formed.
Correct answer: D
Rationale: During telophase, the final stage of mitosis, the separated chromosomes reach opposite poles of the cell. At this stage, a new nuclear envelope forms around each set of chromosomes, creating two distinct nuclei. This marks the completion of cell division. Choices A, B, and C are incorrect because the disappearance of the nuclear envelope typically occurs during prophase, organelles do not double in number during telophase, and chromosomes separate during anaphase, not telophase.
2. Enzymes are typically _ _.
- A. Fats
- B. Proteins
- C. Sugars
- D. Neurons
Correct answer: B
Rationale: Enzymes are typically proteins that act as biological catalysts, speeding up chemical reactions in living organisms. While most enzymes are made of proteins, a few exceptions, known as ribozymes, are made of RNA. Proteins are composed of amino acids arranged in specific sequences that give enzymes their unique shape and functionality. Choice A, 'Fats,' is incorrect as enzymes are not typically composed of fats. Choice C, 'Sugars,' is incorrect as enzymes are not typically composed of sugars. Choice D, 'Neurons,' is incorrect as neurons are a type of cell in the nervous system, not typically associated with enzymes.
3. Where is the genetic code for each person stored?
- A. RNA
- B. DNA
- C. Nucleus
- D. Chromosomes
Correct answer: B
Rationale: The genetic code for each person is stored in DNA. DNA carries all the hereditary information, including unique traits and characteristics. RNA (Choice A) is involved in protein synthesis but does not hold the complete genetic code. The nucleus (Choice C) is a cellular organelle that houses the DNA, but it is not the genetic code itself. Chromosomes (Choice D) are structures made of DNA and proteins, but the genetic code is specifically encoded in the DNA molecule.
4. What happens to glucose during glycolysis?
- A. Its energy is entirely lost.
- B. It splits into molecules of pyruvic acid.
- C. It is stored in NADH.
- D. It joins with molecules of citric acid.
Correct answer: B
Rationale: During glycolysis, glucose undergoes a series of enzymatic reactions in the cytoplasm of the cell, resulting in its breakdown into two molecules of pyruvic acid. This process also generates ATP and NADH as energy carriers. Choice A is incorrect because glucose is not entirely lost, but rather converted into other molecules. Choice C is incorrect because NADH is a product of glycolysis, not a storage form for glucose. Choice D is incorrect as glucose does not join with molecules of citric acid during glycolysis, but rather in subsequent stages of cellular respiration.
5. How should a researcher test the hypothesis that eating chocolate leads to acne in teenagers?
- A. Take 100 teenagers and feed each one a different amount of chocolate daily for 60 days; then test for acne.
- B. Take 100 teenagers and feed 50 two bars of chocolate daily for 60 days while the other 50 eat no chocolate; then test for acne.
- C. Take 1 teenager and feed him or her two bars of chocolate for 30 days and no chocolate for 30 days; then test for acne.
- D. Take 100 teenagers and feed them no chocolate for 30 days and two bars of chocolate apiece for 30 days; then test for acne.
Correct answer: B
Rationale: Option B is the correct approach to test the hypothesis that eating chocolate leads to acne in teenagers. This method involves having a control group (50 teenagers not consuming chocolate) and an experimental group (50 teenagers consuming two bars of chocolate daily), which allows for comparison. By having two distinct groups, researchers can assess the impact of chocolate consumption on acne development. Option A lacks a control group for comparison, making it harder to attribute any observed effects specifically to chocolate consumption. Option C only involves a single subject, which limits the generalizability of the results. Option D, where all teenagers experience both conditions, does not allow for a direct comparison between chocolate consumption and acne development, as all subjects are exposed to both conditions.
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