Nursing Elites

1. Differentiate between gene therapy and genetic engineering in the context of human intervention.

• A. Gene therapy aims to modify existing genes within body cells, while genetic engineering manipulates genes in embryos to be passed on to offspring.
• B. Gene therapy focuses on treating genetic diseases, while genetic engineering enhances desirable traits or eliminates undesirable ones.
• C. Both involve directly altering the DNA sequence, but gene therapy targets somatic cells and genetic engineering modifies germline cells.
• D. There is no fundamental difference; both terms are synonymous.

Correct answer: B

Rationale: A) Incorrect. Gene therapy does aim to modify existing genes within body cells, but genetic engineering does not necessarily manipulate genes in embryos to be passed on to offspring. Genetic engineering can involve modifying genes in any type of cell, not just embryos. B) Correct. Gene therapy is a medical intervention that aims to treat genetic diseases by correcting or replacing faulty genes within an individual's body cells. On the other hand, genetic engineering involves modifying genes to enhance specific traits or eliminate undesirable ones, often in the context of agriculture or biotechnology. C) Incorrect. While both gene therapy and genetic engineering involve altering DNA sequences, the distinction lies in the target cells. Gene therapy targets somatic cells (non-reproductive cells), while genetic engineering typically involves modifying germline cells (reproductive cells that can pass on genetic changes to offspring). D) Incorrect. There is

2. Which of the following statements regarding macrophages is incorrect?

• A. They are found abundantly in the blood
• B. They are larger than neutrophils
• C. They are long-lived
• D. They are made in the bone marrow as monocytes, called macrophages once they reach organs

Correct answer: A

Rationale: The correct answer is A. Macrophages are not found abundantly in the blood; they are present in tissues and organs. Macrophages are tissue-resident immune cells that play a key role in immune responses and are derived from monocytes produced in the bone marrow. Choice B is correct as macrophages are larger than neutrophils. Choice C is correct as macrophages are long-lived cells. Choice D is correct as macrophages originate in the bone marrow as monocytes and differentiate into macrophages once they migrate to various tissues and organs.

3. What property of a substance remains constant regardless of its location in the universe?

• A. Mass
• B. Weight
• C. Density
• D. Volume

Correct answer: A

Rationale: Mass is a measure of the amount of matter in an object and remains constant regardless of its location in the universe. Weight, on the other hand, is the force of gravity acting on an object and can vary depending on the gravitational pull at different locations. Density and volume can also change based on the environment in which an object is placed, making mass the property that remains constant universally. Therefore, the correct answer is mass. Weight changes with the gravitational force of a particular location, density varies with mass and volume, and volume can change depending on the shape or size of the object.

4. Through which structure do the kidneys reabsorb water, salts, and nutrients and return them to the body?

• A. Renal artery
• B. Renal vein
• C. Nephron
• D. Glomerulus

Correct answer: C

Rationale: The question has been corrected to specify the structure responsible for reabsorbing water, salts, and nutrients in the kidneys. The correct answer is the nephron, which is the functional unit of the kidney that performs filtration and reabsorption processes. The renal artery brings blood into the kidney for filtration, the renal vein carries filtered blood away from the kidney, and the glomerulus is a part of the nephron where filtration occurs. Therefore, the nephron is the structure that reabsorbs substances and returns them to the body.

5. What is the role of the diaphragm in the respiratory system?

• A. To regulate blood pressure
• B. To contract and expand the lungs
• C. To produce red blood cells
• D. To absorb oxygen

Correct answer: B

Rationale: The correct answer is B: To contract and expand the lungs. The diaphragm plays a crucial role in the respiratory system by contracting and expanding the lungs. When it contracts, it flattens, increasing the volume of the thoracic cavity and causing air to be drawn into the lungs. Conversely, when it relaxes, it moves back up, decreasing the thoracic cavity volume and pushing air out of the lungs. This process is essential for breathing and the exchange of oxygen and carbon dioxide in the body. Choices A, C, and D are incorrect. The diaphragm is not involved in regulating blood pressure, producing red blood cells, or absorbing oxygen. Its primary function is to aid in respiration by facilitating breathing through its contraction and relaxation movements.

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