Nursing Elites

1. Antigen-antibody binding is the principle behind:

• A. Vaccination
• B. Disinfection
• C. Sterilization
• D. Antibiotic resistance

Correct answer: A

Rationale: Antigen-antibody binding is the principle behind vaccination. When a vaccine containing antigens (weakened or killed pathogens) is introduced into the body, the immune system produces antibodies that bind to these antigens. This binding triggers an immune response, leading to the production of memory cells that provide immunity against future infections by the same pathogen. Vaccination helps the body develop immunity without causing the disease itself, thereby protecting individuals from infectious diseases. Disinfection and sterilization involve different processes to eliminate or reduce pathogens on surfaces or objects. Antibiotic resistance is a phenomenon where bacteria evolve to resist the effects of antibiotics and is not directly related to antigen-antibody binding.

2. Which of the following characteristics is part of a person's genotype?

• A. Brown eyes that appear hazel in the sunlight
• B. The CFTR gene, which causes cystic fibrosis
• C. Black hair that grows rapidly
• D. Being a fast runner

Correct answer: B

Rationale: The correct answer is B. A genotype refers to a person's genetic makeup, which includes specific genes like the CFTR gene responsible for cystic fibrosis. Genes are the units of heredity and are part of an individual's genotype, influencing various traits and characteristics. Choice A, brown eyes that appear hazel in the sunlight, refers to a phenotype, which is the observable characteristics resulting from the interaction of genes and the environment. Choice C, black hair that grows rapidly, also describes a phenotype rather than a genotype. Choice D, being a fast runner, is a trait influenced by a combination of genetic and environmental factors, but it does not directly relate to a specific gene in the genotype.

3. Two mice are both heterozygous for two traits: white fur (Ww) and short fur (Ss). Their offspring are most likely to have which of the following genotypes for these traits?

• A. wwss
• B. WWSS
• C. WwSs
• D. WWSs

Correct answer: C

Rationale: When two mice that are heterozygous for white fur (Ww) and short fur (Ss) mate, they can produce offspring with different combinations of the two traits. The Punnett square for this cross shows that the most likely genotype for the offspring is WwSs. In this case, each offspring receives one allele for white fur (W) and one for short fur (S) from each parent, resulting in a heterozygous genotype for both traits. Choice A (wwss) is incorrect as it represents a homozygous recessive genotype for both traits. Choice B (WWSS) is also incorrect as it represents a homozygous dominant genotype for both traits. Choice D (WWSs) is incorrect as it represents a genotype where one trait is homozygous dominant (W) and the other is heterozygous (S), which is not the most likely outcome based on the given parental genotypes.

4. What is the most common cause of hospital-acquired infections (HAIs)?

• A. Viruses
• B. Bacteria
• C. Fungi
• D. Parasites

Correct answer: B

Rationale: Hospital-acquired infections (HAIs), also known as nosocomial infections, are infections that patients acquire during the course of receiving treatment in a healthcare facility. Among the options provided, bacteria are the most common cause of HAIs. Bacteria such as Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa are known to cause a wide range of infections in healthcare settings. While viruses, fungi, and parasites can also cause HAIs, bacteria are the most prevalent and significant pathogens responsible for these infections. Proper infection control measures, including hand hygiene, environmental cleaning, and antimicrobial stewardship, are essential in preventing and controlling HAIs caused by bacteria.

5. What is the difference between emphysema and chronic bronchitis, both chronic obstructive pulmonary diseases (COPD)?

• A. Emphysema damages alveoli, while chronic bronchitis inflames airways.
• B. Emphysema causes coughing, while chronic bronchitis leads to shortness of breath.
• C. Emphysema is more reversible than chronic bronchitis.
• D. Emphysema affects only smokers, while chronic bronchitis can occur in non-smokers.

Correct answer: A

Rationale: Emphysema is characterized by the destruction of alveoli in the lungs, leading to decreased surface area for gas exchange. Chronic bronchitis, on the other hand, involves inflammation and narrowing of the airways, leading to excessive mucus production and coughing. Therefore, the correct difference between emphysema and chronic bronchitis is that emphysema damages the alveoli, while chronic bronchitis inflames the airways. Choice B is incorrect because chronic bronchitis is associated with coughing, not emphysema. Choice C is incorrect as chronic bronchitis is typically less reversible compared to emphysema. Choice D is incorrect as both emphysema and chronic bronchitis are commonly seen in smokers, but chronic bronchitis can also occur in non-smokers due to other factors such as air pollution or genetic predisposition.

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