HESI A2
HESI A2 Biology Practice Test
1. A child is sick. They have a body temperature that exceeds 37ºC. The body senses this and begins to sweat in order to lower the temperature. What is this an example of?
- A. Positive feedback loop
- B. Negative feedback loop
- C. Both
- D. None of the above
Correct answer: B
Rationale: This is an example of a negative feedback loop. In a negative feedback loop, the body's response (sweating) works to counteract the initial stimulus of a high body temperature by cooling the body down. The goal is to return the body to homeostasis, maintaining a stable internal environment. Positive feedback loops amplify the initial stimulus rather than counteracting it, which is not the case here. Therefore, choices A and C are incorrect. Choice D is also incorrect as the situation described fits the characteristics of a negative feedback loop.
2. Which component of the cell contributes to the protection, communication, and passage of substances into and out of the cell?
- A. Nucleus
- B. Cell membrane
- C. Endoplasmic reticulum
- D. Cytoplasm
Correct answer: B
Rationale: The correct answer is the cell membrane. The cell membrane is responsible for protecting the cell, facilitating communication with the external environment, and regulating the passage of substances into and out of the cell. The nucleus (Choice A) is the control center of the cell and houses the genetic material but is not primarily involved in these functions. The endoplasmic reticulum (Choice C) is involved in protein synthesis and lipid metabolism, not primarily in protection or communication. The cytoplasm (Choice D) is the gel-like substance that fills the cell but does not specifically contribute to protection, communication, or substance passage.
3. Which component is not found in the nucleotide of DNA?
- A. Simple sugar
- B. Nitrogen base
- C. Phosphate group
- D. Citric acid
Correct answer: D
Rationale: Citric acid is not found in the nucleotide of DNA. A DNA nucleotide is composed of a simple sugar (deoxyribose), a nitrogen base (adenine, thymine, cytosine, or guanine), and a phosphate group. Citric acid is not part of DNA nucleotides; instead, it is involved in the citric acid cycle of cellular respiration. Choices A, B, and C are essential components of DNA nucleotides, making them incorrect answers.
4. Which structure might be described as a core of nucleic acid surrounded by a protein coat?
- A. RNA
- B. Virus
- C. Blue-green alga
- D. Saprophyte
Correct answer: B
Rationale: A virus can be described as a core of nucleic acid (either RNA or DNA) surrounded by a protein coat, known as a capsid. This structure distinguishes viruses from other microorganisms such as blue-green algae (Cyanobacteria), fungi known as saprophytes, or individual RNA molecules. Viruses depend on a host cell to replicate and are considered non-living entities due to their inability to carry out metabolic functions independently.
5. How is the plasma membrane arranged?
- A. In a single layer made of proteins
- B. In a double layer made of proteins
- C. In a single layer of phospholipids
- D. In a double layer of phospholipids
Correct answer: D
Rationale: The plasma membrane is arranged in a double layer of phospholipids, known as a phospholipid bilayer. This structure consists of two layers of phospholipid molecules with hydrophilic heads facing the exterior and hydrophobic tails facing the interior, providing a semipermeable barrier for the cell. Choice A is incorrect because the plasma membrane is not made of a single layer of proteins. Choice B is incorrect as the double layer is composed of phospholipids, not proteins. Choice C is incorrect as the plasma membrane is not made of a single layer of phospholipids but rather a double layer.
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