HESI A2
HESI A2 Biology Practice Test
1. A child is sick. They have a body temperature that exceeds 37ºC. The body senses this and begins to sweat in order to lower the temperature. What is this an example of?
- A. Positive feedback loop
- B. Negative feedback loop
- C. Both
- D. None of the above
Correct answer: B
Rationale: This is an example of a negative feedback loop. In a negative feedback loop, the body's response (sweating) works to counteract the initial stimulus of a high body temperature by cooling the body down. The goal is to return the body to homeostasis, maintaining a stable internal environment. Positive feedback loops amplify the initial stimulus rather than counteracting it, which is not the case here. Therefore, choices A and C are incorrect. Choice D is also incorrect as the situation described fits the characteristics of a negative feedback loop.
2. Which names a final step in protein synthesis?
- A. DNA unzips.
- B. Amino acids bond.
- C. Transfer RNA bonds to messenger RNA.
- D. Messenger RNA moves to ribosomes.
Correct answer: B
Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
3. A cell from heart muscle would more than likely contain an unusually high proportion of which of the following?
- A. lysosomes
- B. mitochondria
- C. mRNA
- D. ribosomes
Correct answer: B
Rationale: A cell from heart muscle would more than likely contain an unusually high proportion of mitochondria because the heart muscle requires a significant amount of energy to function properly. Mitochondria are the powerhouse of the cell and are responsible for producing energy in the form of ATP through cellular respiration. Therefore, to meet the high energy demands of the heart muscle, it would need a higher concentration of mitochondria compared to other cell types. Choices A, C, and D are incorrect because while lysosomes, mRNA, and ribosomes are essential components of a cell, they do not play as direct a role in meeting the high energy demands of heart muscle as mitochondria do.
4. Which is not a product of the Krebs cycle?
- A. ATP
- B. Carbon dioxide
- C. Glucose
- D. NADH
Correct answer: C
Rationale: Glucose is not a direct product of the Krebs cycle. Glucose is a starting molecule that undergoes glycolysis outside the mitochondria to produce pyruvate, which then enters the mitochondrial matrix to participate in the Krebs cycle. The Krebs cycle primarily generates ATP, carbon dioxide, and NADH as products. Choices A, B, and D are all products of the Krebs cycle, making them incorrect answers.
5. How do green plants use nitrates in the nitrogen cycle?
- A. To synthesize proteins
- B. To store food
- C. To decompose ammonia
- D. To break down nitrites
Correct answer: A
Rationale: Green plants use nitrates in the nitrogen cycle to synthesize proteins. Nitrogen is an essential component of amino acids, which are the building blocks of proteins. Plants take up nitrates from the soil through their roots and incorporate nitrogen into their proteins through the process of protein biosynthesis. This helps in their growth, development, and overall health. Choice B, 'To store food,' is incorrect because nitrates are primarily used for protein synthesis, not food storage. Choice C, 'To decompose ammonia,' is incorrect as plants do not decompose ammonia but rather utilize it through nitrification. Choice D, 'To break down nitrites,' is incorrect as plants typically convert nitrites into nitrates through a process called nitrate assimilation for protein synthesis.
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