HESI A2
HESI A2 Biology Practice Test
1. A child is sick. They have a body temperature that exceeds 37ÂșC. The body senses this and begins to sweat in order to lower the temperature. What is this an example of?
- A. Positive feedback loop
- B. Negative feedback loop
- C. Both
- D. None of the above
Correct answer: B
Rationale: This is an example of a negative feedback loop. In a negative feedback loop, the body's response (sweating) works to counteract the initial stimulus of a high body temperature by cooling the body down. The goal is to return the body to homeostasis, maintaining a stable internal environment. Positive feedback loops amplify the initial stimulus rather than counteracting it, which is not the case here. Therefore, choices A and C are incorrect. Choice D is also incorrect as the situation described fits the characteristics of a negative feedback loop.
2. Which component of the cell contributes to the protection, communication, and passage of substances into and out of the cell?
- A. Nucleus
- B. Cell membrane
- C. Endoplasmic reticulum
- D. Cytoplasm
Correct answer: B
Rationale: The correct answer is the cell membrane. The cell membrane is responsible for protecting the cell, facilitating communication with the external environment, and regulating the passage of substances into and out of the cell. The nucleus (Choice A) is the control center of the cell and houses the genetic material but is not primarily involved in these functions. The endoplasmic reticulum (Choice C) is involved in protein synthesis and lipid metabolism, not primarily in protection or communication. The cytoplasm (Choice D) is the gel-like substance that fills the cell but does not specifically contribute to protection, communication, or substance passage.
3. In an example of a male with hemophilia and a female carrier, what ratio of the offspring are predicted neither to carry nor to manifest the disease?
- A. 0 females : 1 male
- B. 1 female : 1 male
- C. 1 female : 0 males
- D. 2 females : 1 male
Correct answer: D
Rationale: In this scenario, the male offspring will inherit the Y chromosome from the father and the X chromosome from the carrier mother. As a result, they will not have the hemophilia gene. The female offspring will inherit one X chromosome from the mother, which does not carry the hemophilia gene, and one X chromosome from the father, which does not exist due to the Y chromosome. Therefore, all female offspring will not carry or manifest hemophilia, resulting in a ratio of 2 females to 1 male. Choice A is incorrect because it does not account for the female offspring. Choices B and C are incorrect as they do not reflect the correct ratio based on the inheritance pattern of hemophilia.
4. What is the composition of the plasma membrane?
- A. Proteins
- B. Lipids
- C. Carbohydrates
- D. Nucleotides
Correct answer: B
Rationale: The plasma membrane is composed of lipids, proteins, and carbohydrates. While proteins are an essential component of the plasma membrane, it is not the only constituent. Carbohydrates and lipids also play crucial roles in the structure and function of the plasma membrane. Nucleotides are not part of the primary structural components of the plasma membrane, making this choice incorrect.
5. The cell membrane consists of a bilayer of phospholipids with proteins, cholesterol, and glycoproteins. What does this bilayer create?
- A. Impermeable
- B. Permeable
- C. Selectively permeable
- D. Selectively impermeable
Correct answer: C
Rationale: The correct answer is 'Selectively permeable.' The cell membrane's bilayer structure allows it to be selectively permeable, meaning it can control the passage of substances. This property enables the membrane to regulate the entry and exit of specific molecules, ions, and other substances. Choice A, 'Impermeable,' is incorrect as the cell membrane is not completely impermeable and does allow certain substances to pass through. Choice B, 'Permeable,' is also incorrect as it does not address the selective nature of the membrane. Choice D, 'Selectively impermeable,' is a contradictory term and does not accurately describe the cell membrane's function.
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