HESI A2
HESI A2 Biology Practice Test
1. Which of the following shows how information is transformed to make a protein?
- A. DNA-RNA-protein
- B. gene-chromosome-protein
- C. ATP-amino acid-protein
- D. RNA-DNA-protein
Correct answer: A
Rationale: The correct sequence of events for protein synthesis is that DNA is transcribed into RNA, which is then translated into a protein. This process is known as the central dogma of molecular biology. In this sequence, DNA serves as the template for RNA synthesis (transcription), and the RNA serves as the template for protein synthesis (translation). Choice B is incorrect as genes are segments of DNA that code for proteins, and chromosomes are structures that contain DNA. Choice C is incorrect as ATP is an energy molecule and amino acids are the building blocks of proteins, but they are not directly involved in the synthesis process. Choice D is incorrect because RNA is first transcribed from DNA and then used as a template to produce proteins.
2. What is represented by this formula: 6CO₂ + 6H₂O → C₆H₁₂O₆ + 6O₂?
- A. Glycolysis
- B. Cellular respiration
- C. Photosynthesis
- D. Electronic transport
Correct answer: C
Rationale: The formula represents the process of photosynthesis, where carbon dioxide (CO₂) and water (H₂O) are converted into glucose (C₆H₁₂O₆) and oxygen (O₂) using light energy. This process is essential for plants and some microorganisms to produce food and oxygen. Glycolysis and cellular respiration involve breaking down glucose to produce energy, and the electron transport chain is part of cellular respiration, not photosynthesis.
3. Which cellular structure is largely protective in function?
- A. Mitochondrion
- B. Vacuole
- C. Cell membrane
- D. Ribosome
Correct answer: C
Rationale: The correct answer is C: Cell membrane. The cell membrane, also known as the plasma membrane, is largely protective in function as it serves as a selectively permeable barrier that surrounds the cell, providing structural support and helping to maintain cell integrity. It regulates the movement of substances in and out of the cell, thus protecting the cell from harmful external factors while allowing essential nutrients to enter. Mitochondrion (choice A) is responsible for energy production, not primarily protective. Vacuole (choice B) is mainly involved in storage and transport. Ribosome (choice D) is involved in protein synthesis, not protective functions.
4. A cell containing 12 chromosomes divides into daughter cells in mitosis. How many chromosomes are in each daughter cell?
- A. 3
- B. 6
- C. 12
- D. 24
Correct answer: C
Rationale: During mitosis, the cell undergoes nuclear division without changing the number of chromosomes. Therefore, the daughter cells produced will have the same number of chromosomes as the parent cell. In this case, since the parent cell contains 12 chromosomes, each daughter cell will also have 12 chromosomes. Choices A, B, and D are incorrect because during mitosis, the chromosome number remains the same, and daughter cells inherit the same number of chromosomes as the parent cell.
5. In an example of a male with hemophilia and a female carrier, what ratio of the offspring is predicted to have the disease?
- A. 0 female : 2 males
- B. 1 female : 0 males
- C. 1 female : 2 males
- D. 2 females : 1 male
Correct answer: C
Rationale: In this scenario, the male offspring will inherit the hemophilia trait from their mother due to the sex-linked inheritance pattern. The female offspring will inherit one X chromosome from their mother, becoming carriers of hemophilia. Therefore, the predicted ratio of offspring with the disease would be 1 female as a carrier and 2 males with hemophilia. Choice A is incorrect because there would be male offspring with the disease. Choice B is incorrect as there would be male offspring with hemophilia. Choice D is incorrect as it does not reflect the inheritance pattern of hemophilia.
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