Nursing Elites

1. Which of the following compounds often contains a carboxyl group?

• A. Carbohydrates
• B. Glycolipids
• C. Amino Acids
• D. DNA

Correct answer: C

Rationale: The correct answer is C: Amino Acids. Amino acids, the building blocks of proteins, contain both an amine group and a carboxyl group. The carboxyl group (-COOH) is crucial for the structure and function of proteins as it participates in peptide bond formation. Carbohydrates and DNA do not typically contain carboxyl groups as a functional group. Glycolipids consist of a carbohydrate chain linked to a lipid, but they do not inherently contain a carboxyl group.

2. Endotoxins are toxic substances released by:

• A. Viruses
• B. Bacteria (gram-positive)
• C. Bacteria (gram-negative)
• D. Parasites

Correct answer: C

Rationale: Endotoxins are toxic substances that are part of the outer membrane of the cell wall of gram-negative bacteria. These toxins are released when the bacteria are destroyed or during bacterial growth. Endotoxins can cause a variety of harmful effects in the host, including fever, inflammation, and septic shock. Viruses do not produce endotoxins; they are typically associated with producing viral proteins that can be toxic to host cells. Gram-positive bacteria produce exotoxins, which are different from endotoxins found in gram-negative bacteria. Parasites, though capable of causing diseases, are not typically associated with the production of endotoxins.

3. Antigenic variation, a common strategy used by some viruses, allows them to:

• A. Produce toxins
• B. Evade the immune system
• C. Survive outside a host
• D. Replicate rapidly

Correct answer: B

Rationale: Antigenic variation is a strategy used by some viruses to evade the host's immune response. By constantly changing their surface antigens, viruses can avoid recognition and destruction by the immune system. This allows the virus to persist in the host and continue replicating, leading to prolonged infection and potential transmission to other hosts. Antigenic variation does not directly involve the production of toxins, survival outside a host, or rapid replication, making options A, C, and D incorrect in this context.

4. What is the primary function of antibodies?

• A. Production of white blood cells
• B. Initiation of gluconeogenesis
• C. Promotion of intracellular storage of lipids
• D. Facilitate the breakdown of antigens

Correct answer: D

Rationale: The correct answer is D: Facilitate the breakdown of antigens. Antibodies are protein molecules produced by the immune system in response to the presence of foreign substances, known as antigens, in the body. Antibodies bind to specific antigens and mark them for destruction by other immune cells, thereby helping the body to defend against infections and other threats. Choices A, B, and C are incorrect because antibodies do not have a direct role in the production of white blood cells, initiation of gluconeogenesis, or promotion of intracellular storage of lipids. The primary function of antibodies is to target and facilitate the destruction of antigens in the body.

5. What is the first event to occur in a primary immune response?

• A. Macrophages phagocytose pathogens and present their antigens.
• B. Neutrophils aggregate and act as cytotoxic, nonspecific killers of pathogens.
• C. B lymphocytes make pathogen-specific antibodies.
• D. Helper T cells secrete interleukins to activate pathogen-fighting cells.

Correct answer: A

Rationale: The correct answer is A. The initial event in a primary immune response is the phagocytosis of pathogens by macrophages and the subsequent presentation of their antigens, which is crucial for initiating the adaptive immune response. Neutrophils (Choice B) are also involved in the innate immune response, but they typically respond after macrophages. B lymphocytes (Choice C) produce antibodies later in the adaptive immune response, and Helper T cells (Choice D) help in coordinating the immune response but are not the first cells to act in a primary immune response.

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