HESI A2
HESI A2 Biology 2024
1. Which organelle is the site of energy production?
- A. Mitochondrion
- B. Vacuole
- C. Cell membrane
- D. Ribosome
Correct answer: A
Rationale: The correct answer is A: Mitochondrion. The mitochondrion is the site of energy production in a cell. It is often referred to as the powerhouse of the cell because it is where cellular respiration occurs, generating energy in the form of adenosine triphosphate (ATP) through processes like the citric acid cycle and oxidative phosphorylation. The other organelles listed play different roles in the cell - vacuoles store materials, the cell membrane regulates the movement of substances in and out of the cell, and ribosomes are involved in protein synthesis.
2. What is the typical result of mitosis in humans?
- A. two diploid cells
- B. two haploid cells
- C. four diploid cells
- D. four haploid cells
Correct answer: A
Rationale: The correct answer is A: two diploid cells. Mitosis is a type of cell division that results in two daughter cells, each having the same number of chromosomes as the parent cell. In humans, the typical result of mitosis is the formation of two diploid cells, not haploid or four cells. Choice B, two haploid cells, is incorrect because mitosis produces genetically identical diploid cells. Choices C and D, four diploid cells and four haploid cells, respectively, are incorrect as mitosis results in two daughter cells, not four.
3. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
4. What type of transport moves substances across the cell membrane using energy?
- A. Passive Transport
- B. Active Transport
- C. Facilitated Diffusion
- D. Osmosis
Correct answer: B
Rationale: The correct answer is B: Active Transport. Active transport moves substances across the cell membrane by utilizing energy from the cell, typically in the form of ATP. This process allows the cell to move molecules against their concentration gradient, requiring energy expenditure. Choices A, C, and D are incorrect because passive transport does not require energy input, facilitated diffusion involves the assistance of proteins but does not directly use energy, and osmosis is the diffusion of water molecules specifically, not substances, across a selectively permeable membrane.
5. Which organelle is found in protists but not in monerans?
- A. Golgi apparatus
- B. Chromosome
- C. Cytoplasm
- D. Cell membrane
Correct answer: A
Rationale: The Golgi apparatus is the correct answer. The Golgi apparatus is a cellular organelle responsible for processing and packaging proteins before they are transported to their final destination. Protists, being eukaryotic organisms, have membrane-bound organelles including the Golgi apparatus, which are absent in monerans. Monerans are prokaryotic organisms that lack membrane-bound structures such as the Golgi apparatus. Choices B, C, and D are incorrect as chromosomes, cytoplasm, and cell membranes are present in both protists and monerans.
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